T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Cited by (1,002)

Items 101–200 of 1,002

  1. Emerging strategies to target RAS signaling in human cancer therapy
    Kun Chen, Yalei Zhang, Ling Mei Qian, Peng Wang · 2021 · Journal of Hematology & Oncology
  2. Immune targets and neoantigens for cancer immunotherapy and precision medicine
    Rong‐Fu Wang, Helen Y. Wang · 2016 · Cell Research
  3. Targeting MHC-I molecules for cancer: function, mechanism, and therapeutic prospects
    Wu, Xiangyu, Li, Tianhang, Jiang, Rui, Yang, Xin, Guo, Hongqian, Yang, Rong · 2023 · Molecular Cancer
  4. Perspectives of tumor-infiltrating lymphocyte treatment in solid tumors
    Shuhang Wang, Jingwei Sun, Kun Chen, Peiwen Ma, Qi Lei, Shujun Xing, Zhongzheng Cao, Shujun Sun, Zicheng Yu, Yarong Liu et al. · 2021 · BMC Medicine
  5. Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy
    Zinal S. Chheda, Gary Kohanbash, Kaori Okada, Naznin Jahan, John Sidney, Matteo Pecoraro, Xinbo Yang, Diego A. Carrera, Kira Downey, Shruti Shrivastav et al. · 2017 · The Journal of Experimental Medicine
  6. Best practices for bioinformatic characterization of neoantigens for clinical utility
    Megan M. Richters, Huiming Xia, Katie Marie Campbell, William E. Gillanders, Obi L. Griffith, Malachi Griffith · 2019 · Genome Medicine
  7. Future cancer research priorities in the USA: a Lancet Oncology Commission
    Elizabeth M. Jaffee, Chi Van Dang, David B. Agus, Brian Michael Alexander, Kenneth Carl Anderson, Alan Ashworth, Anna D. Barker, Roshan Bastani, Sangeeta N. Bhatia, Jeffrey A. Bluestone et al. · 2017 · The Lancet Oncology
  8. Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy
    Rami Yossef, Eric Tran, Drew C. Deniger, Alena Gros, Anna Pasetto, Maria R. Parkhurst, Jared J. Gartner, Todd D. Prickett, Gal Cafri, Paul F. Robbins et al. · 2018 · JCI Insight
  9. Tumor Infiltrating Lymphocyte (TIL) Therapy for Solid Tumor Treatment: Progressions and Challenges
    Yueshui Zhao, Jian Ming Deng, Shuangfeng Rao, Sipeng Guo, Jing Shen, Fukuan Du, Xu Wu, Yu Chen, Mingxing Li, Meijuan Chen et al. · 2022 · Cancers
  10. Stem Cell Plasticity and Dormancy in the Development of Cancer Therapy Resistance
    Maria Laura De Angelis, Federica Francescangeli, Filippo La Torre, Ann Zeuner · 2019 · Frontiers in Oncology
  11. KRAS Oncogenic Signaling Extends beyond Cancer Cells to Orchestrate the Microenvironment
    Dias Carvalho, Patrícia, Guimarães, Carlos F., Cardoso, Ana P., Mendonça, Susana, Costa, Ângela M, Oliveira, Maria J., Velho, Sérgia · 2018 · Cancer Research
  12. Applications of Immunogenomics to Cancer
    X. Shirley Liu, Elaine R. Mardis · 2017 · Cell
  13. Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia
    Dyantha I. van der Lee, Rogier M. Reijmers, Maria W. Honders, Renate S. Hagedoorn, Rob C. M. de Jong, Michel G.D. Kester, Dirk M. van der Steen, Arnoud H. de Ru, Christiaan Kweekel, Helena M. Bijen et al. · 2019 · Journal of Clinical Investigation
  14. Gene editing for immune cell therapies
    Stefanie R. Bailey, Marcela Valderrama Maus · 2019 · Nature Biotechnology
  15. Cancer immunotherapy resistance based on immune checkpoints inhibitors: Targets, biomarkers, and remedies
    Elísabeth Pérez-Ruiz, Ignacio Melero, Joanna Kopecka, Ana Bela Sarmento‐Ribeiro, Marilina García‐Aranda, Javier De Las Rivas · 2020 · Drug Resistance Updates
  16. Tumor-infiltrating human CD4 + regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity
    Mojgan Ahmadzadeh, Anna Pasetto, Lee Jia, Drew C. Deniger, Sanja Stevanović, Paul F. Robbins, Steven A. Rosenberg · 2019 · Science Immunology
  17. KRAS-mutant non-small cell lung cancer: Converging small molecules and immune checkpoint inhibition
    Helen Adderley, Fiona Helen Blackhall, Colin R. Lindsay · 2019 · EBioMedicine
  18. Breast Cancers Are Immunogenic: Immunologic Analyses and a Phase II Pilot Clinical Trial Using Mutation-Reactive Autologous Lymphocytes
    Nikolaos Zacharakis, Lutfi Huq, Samantha J. Seitter, Sanghyun Peter Kim, Jared J. Gartner, Sivasish Sindiri, Victoria K. Hill, Yong F. Li, Biman C. Paria, Satyajit Ray et al. · 2022 · Journal of Clinical Oncology
  19. Targeting public neoantigens for cancer immunotherapy
    Alexander H. Pearlman, Michael S. Hwang, Maximilian F. Konig, Emily Han-Chung Hsiue, Jacqueline Douglass, Sarah R. DiNapoli, Brian J. Mog, Chetan Bettegowda, Drew M. Pardoll, Sandra B. Gabelli et al. · 2021 · Nature Cancer
  20. Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment
    Irene Scarfò, Marcela Valderrama Maus · 2017 · Journal for ImmunoTherapy of Cancer
  21. Tumor Evolution as a Therapeutic Target
    Nabil Amirouchene-Angelozzi, Charles Swanton, Alberto Bardelli · 2017 · Cancer Discovery
  22. Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors
    Sanghyun Peter Kim, Nolan R. Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J. Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C. Deniger et al. · 2022 · Cancer Immunology Research
  23. Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors
    Lee, Jessica K., Sivakumar, Smruthy, Schrock, Alexa B., Madison, Russell, Fabrizio, David, Gjoerup, Ole, Ross, Jeffrey S., Frampton, Garrett M., Napalkov, Pavel, Montesion, Meagan et al. · 2022 · npj Precision Oncology
  24. Tumor-infiltrating lymphocytes: Warriors fight against tumors powerfully
    Baisheng Lin, Likun Du, Hongmei Li, Xiao Ming Zhu, Liao Cui, Xiaosong Li · 2020 · Biomedicine & Pharmacotherapy
  25. Adoptive Cell Therapy Targeting Neoantigens: A Frontier for Cancer Research
    Zhidong Wang, Yu J Cao · 2020 · Frontiers in Immunology
  26. Immunotherapies: Exploiting the Immune System for Cancer Treatment
    Jeffrey Koury, Mariana Lucero, Caleb Cato, Lawrence Chang, Joseph Geiger, Denise Henry, Jennifer Hernandez, Fion Hung, Preet Kaur, Garrett Teskey et al. · 2018 · Journal of Immunology Research
  27. Colorectal Cancers: An Update on Their Molecular Pathology
    Kentaro Inamura · 2018 · Cancers
  28. Tumor immune microenvironment in head and neck cancers
    Samantha M. Y. Chen, Alexandra L. Krinsky, Rachel A. Woolaver, Xiaoguang Wang, Zhangguo Chen, Jing Hong Wang · 2020 · Molecular Carcinogenesis
  29. RAS: Striking at the Core of the Oncogenic Circuitry
    Gimple, Ryan C., Wang, Xiuxing · 2019 · Frontiers in Oncology
  30. Bispecific antibodies targeting mutant RAS neoantigens
    Douglass, Jacqueline, Hsiue, Emily Han-Chung, Mog, Brian J., Hwang, Michael S., DiNapoli, Sarah R., Pearlman, Alexander H., Miller, Michelle S., Wright, Katharine M., Azurmendi, P. Aitana, Wang, Qing et al. · 2021 · Science Immunology
  31. The current understanding on the impact of KRAS on colorectal cancer
    Meng, Mingjing, Zhong, Keying, Jiang, Ting, Liu, Zhongqiu, Kwan, Hiu Yee, Su, Tao · 2021 · Biomedicine & Pharmacotherapy
  32. Mismatch Repair-Deficient Colorectal Cancer: Building on Checkpoint Blockade
    Zhaohui Jin, Frank A. Sinicrope · 2022 · Journal of Clinical Oncology
  33. Tumor Burden and Immunotherapy: Impact on Immune Infiltration and Therapeutic Outcomes
    Samuel I. Kim, Christopher R. Cassella, Katelyn T. Byrne · 2021 · Frontiers in Immunology
  34. Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients
    Gal Cafri, Rami Yossef, Anna Pasetto, Drew C. Deniger, Yong‐Chen Lu, Maria R. Parkhurst, Jared J. Gartner, Lee Jia, Satyajit Ray, Lien T. Ngo et al. · 2019 · Nature Communications
  35. Tumor-infiltrating lymphocytes for treatment of solid tumors: It takes two to tango?
    Mohammad Hossein Kazemi, Maryam Sadri, Alireza Najafi, Ali R. Rahimi, Zeinab Baghernejadan, Hossein Khorramdelazad, Reza Falak · 2022 · Frontiers in Immunology
  36. Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine
    Conway, Jake R., Kofman, Eric, Mo, Shirley S., Elmarakeby, Haitham, Van Allen, Eliezer · 2018 · Genome Medicine
  37. Predicting Antigen Presentation—What Could We Learn From a Million Peptides?
    David Gfeller, Michal Bassani‐Sternberg · 2018 · Frontiers in Immunology
  38. Technological advances in cancer immunity: from immunogenomics to single‐cell analysis and artificial intelligence
    Xu, Ying, Su, Guan-Hua, Ma, Ding, Xiao, Yi, Shao, Zhi-Ming, Jiang, Yi-Zhou · 2021 · Signal Transduction and Targeted Therapy
  39. Strategies for Increasing Pancreatic Tumor Immunogenicity
    Burles Avner Johnson, Mark M. Yarchoan, Valerie Lee, Daniel A. Laheru, Elizabeth M. Jaffee · 2017 · Clinical Cancer Research
  40. The improbable targeted therapy: KRAS as an emerging target in non-small cell lung cancer (NSCLC)
    Ravi Salgia, Rebecca R. Pharaon, Isa Mambetsariev, Arin Nam, Martin Sattler · 2021 · Cell Reports Medicine
  41. Update on Tumor Neoantigens and Their Utility: Why It Is Good to Be Different
    Chung‐Han Lee, Roman Yelensky, Karin U. Jooss, Timothy An-thy Chan · 2018 · Trends in Immunology
  42. A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results
    Amy Rappaport, Chrisann Kyi, Monica Lane, Meghan G. Hart, Melissa Lynne Johnson, Brian S. Henick, Chih‐Yi Liao, Amit Mahipal, Ardaman P. Shergill, Alexander I. Spira et al. · 2024 · Nature Medicine
  43. Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma
    Trujillo, Jonathan A., Luke, Jason J., Zha, Yuanyuan, Segal, Jeremy P., Ritterhouse, Lauren L., Spranger, Stefani, Matijevich, Karen, Gajewski, Thomas F. · 2019 · Journal for ImmunoTherapy of Cancer
  44. Neoantigen prediction and computational perspectives towards clinical benefit: recommendations from the ESMO Precision Medicine Working Group
    Leticia De Mattos‐Arruda, Miguél Vázquez, Francesca Finotello, Rosalba Lepore, E. Porta, Jasreet Hundal, Pep Amengual-Rigo, Charlotte K.Y. Ng, Alfonso Valencia, Jorge Carrillo et al. · 2020 · Annals of Oncology
  45. T cell receptor therapeutics: immunological targeting of the intracellular cancer proteome
    Christopher Austin Klebanoff, Smita S. Chandran, Brian M. Baker, Sergio A. Quezada, Antoni Ribas · 2023 · Nature Reviews Drug Discovery
  46. Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer
    Winifred M. Lo, Maria R. Parkhurst, Paul F. Robbins, Eric Tran, Yong‐Chen Lu, Lee Jia, Jared J. Gartner, Anna Pasetto, Drew C. Deniger, Parisa Malekzadeh et al. · 2019 · Cancer Immunology Research
  47. Molecular mechanisms of the preventable causes of cancer in the United States
    Erica A. Golemis, Paul A. Scheet, Tim N. Beck, Eward M. Scolnick, David J. Hunter, Ernest T. Hawk, Nancy H. Hopkins · 2018 · Genes & Development
  48. DeepHLApan: A Deep Learning Approach for Neoantigen Prediction Considering Both HLA-Peptide Binding and Immunogenicity
    Jingcheng Wu, Wenzhe Wang, Jiucheng Zhang, Binbin Zhou, Wenyi Zhao, Zhixi Su, Xun Gu, Jian Wu, Zhan Mei Zhou, Shuqing Chen · 2019 · Frontiers in Immunology
  49. KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer
    Neeraj Lal, Brian S. White, Ghaleb Goussous, Oliver J. Pickles, Mike J. Mason, Andrew David Beggs, Philippe Tanière, Benjamin E. Willcox, Justin Guinney, Gary Middleton · 2017 · Clinical Cancer Research
  50. Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes
    Alena Gros, Eric Tran, Maria R. Parkhurst, Sadia Ilyas, Anna Pasetto, Eric M. Groh, Paul F. Robbins, Rami Yossef, Andrea García-Garijo, Carlos Alberto Fajardo et al. · 2019 · Journal of Clinical Investigation
  51. Colorectal cancer immunotherapy-Recent progress and future directions
    Wen Zhao, Lujia Jin, Peng Chen, Dingchang Li, Wenxing Gao, Guanglong Dong · 2022 · Cancer Letters
  52. T-cell Responses to TP53 “Hotspot” Mutations and Unique Neoantigens Expressed by Human Ovarian Cancers
    Drew C. Deniger, Anna Pasetto, Paul F. Robbins, Jared J. Gartner, Todd D. Prickett, Biman C. Paria, Parisa Malekzadeh, Lee Jia, Rami Yossef, Michelle M. Langhan et al. · 2018 · Clinical Cancer Research
  53. Antigen processing and presentation in cancer immunotherapy
    Maxwell Y Lee, Jun W. Jeon, Cem M. Sievers, Clint Tanner Allen · 2020 · Journal for ImmunoTherapy of Cancer
  54. Exploiting the therapeutic implications of KRAS inhibition on tumor immunity
    Molina-Arcas, Miriam, Downward, Julian · 2024 · Cancer Cell
  55. Neoantigen Vaccine Delivery for Personalized Anticancer Immunotherapy
    Yugang Guo, Kewen Lei, Li Tang · 2018 · Frontiers in Immunology
  56. Immunotherapy for Colorectal Cancer
    Patrick McKay Boland, Wen Ma · 2017 · Cancers
  57. Neoantigen Dissimilarity to the Self-Proteome Predicts Immunogenicity and Response to Immune Checkpoint Blockade
    Lee P. Richman, Robert H. Vonderheide, Andrew J. Rech · 2019 · Cell Systems
  58. Detecting Tumor Antigen-Specific T Cells via Interaction-Dependent Fucosyl-Biotinylation
    Liu, Zilei, Li, Jie P., Chen, Mingkuan, Wu, Mengyao, Shi, Yujie, Li, Wei, Teijaro, John R., Wu, Peng · 2020 · Cell
  59. Cell Therapy With TILs: Training and Taming T Cells to Fight Cancer
    Amrendra Kumar, Reese Watkins, Anna E. Vilgelm · 2021 · Frontiers in Immunology
  60. Colorectal cancer vaccines: Tumor-associated antigens vs neoantigens
    Sandra Wagner, Christina Susanne Mullins, Michael Linnebacher · 2018 · World Journal of Gastroenterology
  61. Hallmarks of Resistance to Immune-Checkpoint Inhibitors
    Maria Karasarides, Alexandria P. Cogdill, Paul B. Robbins, Michaela Bowden, Elizabeth M. Burton, Lisa Helene Butterfield, Alessandra Cesano, Christian Hammer, Cara Haymaker, Christine E. Horak et al. · 2022 · Cancer Immunology Research
  62. Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas
    Devin Dersh, James D. Phelan, Megan E. Gumina, Boya Wang, Jesse H. Arbuckle, Jaroslav Hollý, Rigel J. Kishton, Tovah E. Markowitz, Mina O. Seedhom, Nathan Fridlyand et al. · 2020 · Immunity
  63. Transcriptomic profiles of neoantigen-reactive T cells in human gastrointestinal cancers
    Chunhong Zheng, Joseph N Fass, Yi-Ping Shih, Andrew J. Gunderson, Nelson Sanjuan Silva, Huayu Huang, Brady M. Bernard, Venkatesh Rajamanickam, Joseph Slagel, Carlo Bruno Bifulco et al. · 2022 · Cancer Cell
  64. Immune regulation of metastasis: mechanistic insights and therapeutic opportunities
    Olga S. Blomberg, Lorenzo Spagnuolo, Karin E. de Visser · 2018 · Disease Models & Mechanisms
  65. High-affinity neoantigens correlate with better prognosis and trigger potent antihepatocellular carcinoma (HCC) activity by activating CD39 + CD8 + T cells
    Ting Liu, Jizhou Tan, Minhao Wu, Wenzhe Fan, Jialiang Wei, Bowen Zhu, Jian Ming Guo, Shutong Wang, Penghui Zhou, Hui Zhang et al. · 2020 · Gut
  66. Precision oncology in the age of integrative genomics
    Chandan Kumar‐Sinha, Arul M. Chinnaiyan · 2018 · Nature Biotechnology
  67. Determinants for Neoantigen Identification
    Andrea García-Garijo, Carlos Alberto Fajardo, Alena Gros · 2019 · Frontiers in Immunology
  68. A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy
    Zhang, Ziyang, Rohweder, Peter J., Ongpipattanakul, Chayanid, Basu, Koli, Bohn, Markus-Frederik, Dugan, Eli J., Steri, Veronica, Hann, Byron, Shokat, Kevan M., Craik, Charles S. · 2022 · Cancer Cell
  69. Pancreatic ductal adenocarcinoma: State-of-the-art 2017 and new therapeutic strategies
    Marta Chiaravalli, Michele Reni, Eileen Mary O'Reilly · 2017 · Cancer Treatment Reviews
  70. Targeting KRAS Mutant Non-Small-Cell Lung Cancer: Past, Present and Future
    Iris Z. Uras, Herwig Peter Moll, Emilio Casanova · 2020 · International Journal of Molecular Sciences
  71. Neoantigen quality, not quantity
    Nicholas McGranahan, Charles Swanton · 2019 · Science Translational Medicine
  72. Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA
    Smita S. Chandran, Jiaqi Ma, Martin G. Klatt, Friederike Dündar, Chaitanya Bandlamudi, Pedram Razavi, Hannah Yong Wen, Britta Weigelt, Paul Zumbo, Si Ning Fu et al. · 2022 · Nature Medicine
  73. The landscape of T cell antigens for cancer immunotherapy
    Aviyah Peri, Nadja Salomon, Yochai Wolf, Sebastian Kreiter, Mustafa Diken, Yardena Samuels · 2023 · Nature Cancer
  74. New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness
    Yang, Haitang, Liang, Shun-Qing, Schmid, Ralph A., Peng, Ren-Wang · 2019 · Frontiers in Oncology
  75. Neoantigenic Potential of Complex Chromosomal Rearrangements in Mesothelioma
    Aaron Scott Mansfield, Tobias Peikert, James B. Smadbeck, Julia B.M. Udell, Enrique Garcia-Rivera, Laura R. Elsbernd, Courtney L. Erskine, Virginia P. Van Keulen, Farhad Kosari, Stephen J. Murphy et al. · 2018 · Journal of Thoracic Oncology
  76. Adoptive cellular immunotherapy for solid neoplasms beyond CAR-T
    Qiaofei Liu, Jiayi Li, Huaijin Zheng, Sen Yang, Yuze Hua, Nan Huang, Jorg H. Kleeff, Quan Liao, Wenming Wu · 2023 · Molecular Cancer
  77. Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma
    Joshua R. Veatch, Sylvia M. Lee, Matthew Fitzgibbon, I‐Ting Chow, Brenda L. Jesernig, Tom Schmitt, Ying Kong, Julia Kargl, A. McGarry Houghton, John A. Thompson et al. · 2018 · Journal of Clinical Investigation
  78. High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D
    Malcolm J. W. Sim, Jinghua Lu, Matthew K. Spencer, Francis R. Hopkins, Eric Tran, Steven A. Rosenberg, Eric O. Long, Peter D. Sun · 2020 · Proceedings of the National Academy of Sciences
  79. The expanding role of immunotherapy
    Juan Martín-Liberal, María Ochoa de Olza, Cinta Hierro, Alena Gros, Jordi Ahnert Rodon, Josep M. Tabernero · 2017 · Cancer Treatment Reviews
  80. RAS signaling in carcinogenesis, cancer therapy and resistance mechanisms
    Xiaojuan Yang, Hong Kun Wu · 2024 · Journal of Hematology & Oncology
  81. The Cancer Immunogram as a Framework for Personalized Immunotherapy in Urothelial Cancer
    Nick van Dijk, Samuel Aaron Funt, Christian U. Blank, Thomas B. Powles, Jonathan E. Rosenberg, Michiel S. van der Heijden · 2018 · European Urology
  82. Computational Prediction and Validation of Tumor-Associated Neoantigens
    Vladimir Roudko, Benjamin D. Greenbaum, Nina Bhardwaj · 2020 · Frontiers in Immunology
  83. Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance
    Li, Qing-Hai, Wang, Ying-Zhao, Tu, Jian, Liu, Chu-Wei, Yuan, Yu-Jie, Lin, Run, He, Wei-Ling, Cai, Shi-Rong, He, Yu-Long, Ye, Jin-Ning · 2020 · Gastroenterology Report
  84. Recent updates in cancer immunotherapy: a comprehensive review and perspective of the 2018 China Cancer Immunotherapy Workshop in Beijing
    Zihai Li, Wenru Song, Mark P. Rubinstein, Delong Liu · 2018 · Journal of Hematology & Oncology
  85. Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens
    Parisa Malekzadeh, Rami Yossef, Gal Cafri, Biman C. Paria, Frank J. Lowery, Mohammad S. Jafferji, Meghan L. Good, Abraham Sachs, Amy R. Copeland, Sanghyun Peter Kim et al. · 2020 · Clinical Cancer Research
  86. KRAS G12D targeted therapies for pancreatic cancer: Has the fortress been conquered?
    Sahar F. Bannoura, Husain Yar Khan, Asfar Sohail Azmi · 2022 · Frontiers in Oncology
  87. Predictive biomarkers for response to immune checkpoint inhibition
    Benjamin Shum, James Larkin, Samra Turajlic · 2021 · Seminars in Cancer Biology
  88. Mutation-Derived Neoantigens for Cancer Immunotherapy
    John C. Castle, Mohamed Uduman, Simarjot Singh Pabla, Robert Benjamin Stein, Jennifer S. Buell · 2019 · Frontiers in Immunology
  89. Gene signature of antigen processing and presentation machinery predicts response to checkpoint blockade in non-small cell lung cancer (NSCLC) and melanoma
    Jeffrey C. Thompson, Christiana W. Davis, Charuhas G. Deshpande, Wei‐Ting Hwang, Seth Jeffries, Alexander Chan Chi Huang, Tara C. Mitchell, Corey Jay Langer, Steven Μ. Albelda · 2020 · Journal for ImmunoTherapy of Cancer
  90. Adoptive cell therapy for cancer treatment
    Shi Du, Jingyue Yan, Yonger Xue, Yichen Zhong, Yizhou Dong · 2023 · Exploration
  91. Endogenous T cells prevent tumor immune escape following adoptive T cell therapy
    Scott R. Walsh, Boris Simovic, Lan Chen, Donald J. Bastin, Andrew Nguyen, Kyle B. Stephenson, Talveer S. Mandur, Jonathan L. Bramson, Brian Dennis Lichty, Yonghong Wan · 2019 · Journal of Clinical Investigation
  92. Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting
    Bear, Adham S., Blanchard, Tatiana, Cesare, Joseph, Ford, Michael J., Richman, Lee P., Xu, Chong, Baroja, Miren L., McCuaig, Sarah, Costeas, Christina, Gabunia, Khatuna et al. · 2021 · Nature Communications
  93. Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
    Andrew J. Poole, Vijaykumar Karuppiah, Annabelle Hartt, Jaafar N. Sleiman Haidar, Sylvie Moureau, Tomasz Dobrzycki, Conor Hayes, Christopher N. Rowley, J.C. Dias, Stephen J Harper et al. · 2022 · Nature Communications
  94. Machine learning methods and harmonized datasets improve immunogenic neoantigen prediction
    Markus Müller, Florian Huber, Marion Arnaud, Anne I. Kraemer, Emma Ricart Altimiras, Justine Michaux, Marie Taillandier-Coindard, Johanna Chiffelle, Baptiste Murgues, Talita Gehret et al. · 2023 · Immunity
  95. TCRmodel2: high-resolution modeling of T cell receptor recognition using deep learning
    Rui Ming Yin, Helder Veras Ribeiro Filho, Valerie C. L. Lin, Ragul Gowthaman, Melyssa Cheung, Brian G. Pierce · 2023 · Nucleic Acids Research
  96. Immunotherapy for Glioblastoma: Adoptive T-cell Strategies
    Bryan D. Choi, Marcela Valderrama Maus, Carl H. June, John Howard Sampson · 2018 · Clinical Cancer Research
  97. TSNAdb: A Database for Tumor-Specific Neoantigens from Immunogenomics Data Analysis
    Jingcheng Wu, Wenyi Zhao, Binbin Zhou, Zhixi Su, Xun Gu, Zhan Mei Zhou, Shuqing Chen · 2018 · Genomics Proteomics & Bioinformatics
  98. Induction of neoantigen-reactive T cells from healthy donors
    Muhammad Ali, Zsófia Földvári, Eirini Giannakopoulou, Maxi-Lu Böschen, Erlend Strønen, Weiwen Yang, Mireille Toebes, Benjamin Schubert, Oliver Kohlbacher, Ton N. Schumacher et al. · 2019 · Nature Protocols
  99. Mechanisms of tumor resistance to immune checkpoint blockade and combination strategies to overcome resistance
    Xiaoting Zhou, Yanghong Ni, Xiao Liang, Yi Lin, Biao An, Xiang He, Xia Zhao · 2022 · Frontiers in Immunology
  100. Cancer cell-intrinsic mechanisms driving acquired immune tolerance
    Ehsan Ghorani, Charles Swanton, Sergio A. Quezada · 2023 · Immunity