Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing

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Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study

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Evolution and transmission of drug-resistant tuberculosis in a Russian population

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Same-Day Diagnostic and Surveillance Data for Tuberculosis via Whole-Genome Sequencing of Direct Respiratory Samples

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A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis

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Ethambutol resistance in Mycobacterium tuberculosis: critical role of embB mutations

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Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study

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GenomegaMap: Within-Species Genome-Wide dN/dS Estimation from over 10,000 Genomes

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Antibiotic resistance determination using Enterococcus faecium whole-genome sequences: a diagnostic accuracy study using genotypic and phenotypic data

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Tuberculosis endotypes to guide stratified host-directed therapy

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Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study

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Comparisons of whole-genome sequencing and phenotypic drug susceptibility testing for Mycobacterium tuberculosis causing MDR-TB and XDR-TB in Thailand

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Whole-genome sequencing of Mycobacterium tuberculosis for prediction of drug resistance

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Exact mapping of Illumina blind spots in the Mycobacterium tuberculosis genome reveals platform-wide and workflow-specific biases

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Identification and Characterization of Genetic Determinants of Isoniazid and Rifampicin Resistance in Mycobacterium tuberculosis in Southern India

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Genomic Prediction of Antimicrobial Resistance: Ready or Not, Here It Comes!

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Mycobacterial fatty acid catabolism is repressed by FdmR to sustain lipogenesis and virulence

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A Recombinase Polymerase Amplification-Coupled Cas12a Mutant-Based Module for Efficient Detection of Streptomycin-Resistant Mutations in Mycobacterium tuberculosis

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Design of Multidrug-Resistant Tuberculosis Treatment Regimens Based on DNA Sequencing

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A Rapid Drug Resistance Genotyping Workflow for Mycobacterium tuberculosis, Using Targeted Isothermal Amplification and Nanopore Sequencing

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Making cough count in tuberculosis care

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A genomic data resource for predicting antimicrobial resistance from laboratory-derived antimicrobial susceptibility phenotypes

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WGS more accurately predicts susceptibility of Mycobacterium tuberculosis to first-line drugs than phenotypic testing

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Implementation of whole genome sequencing for tuberculosis diagnostics in a low-middle income, high MDR-TB burden country

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Clofazimine for the treatment of multidrug-resistant tuberculosis

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Multi-Omics Technologies Applied to Tuberculosis Drug Discovery

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Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS

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The catalogue of Mycobacterium tuberculosis mutations associated with drug resistance to 12 drugs in China from a nationwide survey: a genomic analysis

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Linkage disequilibrium between rare mutations

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Identifying isoniazid resistance markers to guide inclusion of high-dose isoniazid in tuberculosis treatment regimens

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Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis

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Origin and Global Expansion of Mycobacterium tuberculosis Complex Lineage 3

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TB-DROP: deep learning-based drug resistance prediction of Mycobacterium tuberculosis utilizing whole genome mutations

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Multi-Label Random Forest Model for Tuberculosis Drug Resistance Classification and Mutation Ranking

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Clinical and public health utility of Mycobacterium tuberculosis whole genome sequencing

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The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions

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Whole genomic sequencing as a tool for diagnosis of drug and multidrug-resistance tuberculosis in an endemic region in Mexico

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Whole genome enrichment approach for rapid detection of Mycobacterium tuberculosis and drug resistance-associated mutations from direct sputum sequencing

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Unraveling the mechanisms of intrinsic drug resistance in Mycobacterium tuberculosis

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Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine-learning approaches

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Genotypic and phenotypic comparison of drug resistance profiles of clinical multidrug-resistant Mycobacterium tuberculosis isolates using whole genome sequencing in Latvia

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A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates

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Messages from the first International Conference on Clinical Metagenomics (ICCMg)

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The past, present and future of ancient bacterial DNA

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Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China

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Whole genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates collected in the Czech Republic, 2005–2020

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Diagnosis and Management of Multidrug-Resistant Tuberculosis in Children: A Practical Approach

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Whole Genome Sequencing Results Associated with Minimum Inhibitory Concentrations of 14 Anti-Tuberculosis Drugs among Rifampicin-Resistant Isolates of Mycobacterium Tuberculosis from Iran

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Characterization of pncA Mutations and Prediction of PZA Resistance in Mycobacterium tuberculosis Clinical Isolates From Chongqing, China

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Perspectives for systems biology in the management of tuberculosis

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The Global Success of Mycobacterium tuberculosis Modern Beijing Family Is Driven by a Few Recently Emerged Strains

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Towards a post-pandemic future for global pathogen genome sequencing

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FLASH-TB: an Application of Next-Generation CRISPR to Detect Drug Resistant Tuberculosis from Direct Sputum

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Identification of Mycobacterium tuberculosis Resistance to Common Antibiotics: An Overview of Current Methods and Techniques

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A comparative study of antibiotic resistance patterns in Mycobacterium tuberculosis

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Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis

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Pharmacologic management of Mycobacterium ulcerans infection

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DNA Thermo-Protection Facilitates Whole-Genome Sequencing of Mycobacteria Direct from Clinical Samples

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Population-based inference of aminoglycoside resistance mechanisms in Escherichia coli

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Tuberculosis, HIV, and viral hepatitis diagnostics in eastern Europe and central Asia: high time for integrated and people-centred services

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Unexpected diversity of CRISPR unveils some evolutionary patterns of repeated sequences in Mycobacterium tuberculosis

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Antimicrobial resistance prediction by clinical metagenomics in pediatric severe pneumonia patients

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Automated detection of bacterial growth on 96-well plates for high-throughput drug susceptibility testing of Mycobacterium tuberculosis

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An accessible, efficient and global approach for the large-scale sequencing of bacterial genomesPreprint

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Building the Framework for Standardized Clinical Laboratory Reporting of Next-generation Sequencing Data for Resistance-associated Mutations in Mycobacterium tuberculosis Complex

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How To Optimally Combine Genotypic and Phenotypic Drug Susceptibility Testing Methods for Pyrazinamide

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Overcoming the Challenges of Pyrazinamide Susceptibility Testing in Clinical Mycobacterium tuberculosis Isolates

Mok, S., Roycroft, E., Flanagan, P. R., Montgomery, L., Borroni, E., Rogers, T. R., & Fitzgibbon, M. M. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02617-20 · Cited by 24

Tuberculosis drug resistance profiling based on machine learning: A literature review

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Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan

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Mycobacterium tuberculosisComplex Lineage 3 as Causative Agent of Pulmonary Tuberculosis, Eastern Sudan1

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Limited Capability for Testing Mycobacterium tuberculosis for Susceptibility to New Drugs

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