Overall Survival with Osimertinib in Untreated, EGFR -Mutated Advanced NSCLC
Ramalingam, Suresh S., Vansteenkiste, Johan, Planchard, David, Cho, Byoung Chul, Gray, Jhanelle E., Ohe, Yuichiro, Zhou, Caicun, Reungwetwattana, Thanyanan +16 more·2020·New England Journal of Medicine
Cited by (1,002)
Items 601–700 of 1,002
- Rebiopsy in advanced non-small cell lung cancer, clinical relevance and prognostic implicationsMatthias Scheffler, Marcel Wiesweg, Sebastian Yves Friedrich Michels, Lucia Nogová, Anna Kron, Thomas Herold, Andreas Hans Scheel, Martin Metzenmacher, Wilfried Eberhardt, Henning Reis et al. · 2022 · Lung Cancer
- Optimizing the clinical management of EGFR-mutant advanced non-small cell lung cancer: a literature reviewFrancesco Passiglia, Paolo Bironzo, Valentina Bertaglia, Angela Listì, Edoardo Garbo, Giorgio V. Scagliotti · 2022 · Translational Lung Cancer Research
- Trametinib in Patients With NF1-, GNAQ-, or GNA11-Mutant Tumors: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols S1 and S2Kari Braun Wisinski, Yael Flamand, Melissa Ann Wilson, Jason J. Luke, Hussein A. Tawbi, Fangxin Hong, Edith Peterson Mitchell, James A. Zwiebel, Helen Chen, Robert J. Gray et al. · 2023 · JCO Precision Oncology
- Targeted treatment for unresectable EGFR mutation-positive stage III non-small cell lung cancer: Emerging evidence and future perspectivesTerufumi Kato, Ignacio Casarini, Manuel Cobo, Corinne Faivre Finn, Fiona Hegi‐Johnson, Shun Lü, Mustafa Özgüroğlu, Suresh S. Ramalingam · 2023 · Lung Cancer
- Furmonertinib for EGFR-mutant advanced non-small cell lung cancer: a glittering diamond in the rough of EGFR-TKIJianghua Ding, Xingjing Ding, Jiao Zeng, Xiaoqun Liu · 2024 · Frontiers in Pharmacology
- A Real-World Study of Patient Characteristics and Clinical Outcomes in EGFR Mutated Lung Cancer Treated with First-Line Osimertinib: Expanding the FLAURA Trial Results into Routine Clinical PracticeHollis Viray, Andrew J. Piper‐Vallillo, Page C. Widick, Emmeline C. Academia, Meghan Shea, Deepa Rangachari, Paul A. VanderLaan, Susumu S. Kobayashi, Daniel Botelho Costa · 2024 · Cancers
- New Treatment Options for Patients With Oncogene-Addicted Non–Small Cell Lung Cancer Focusing on EGFR-Mutant TumorsStephanie P.L. Saw, Xiuning Le, Lizza E.L. Hendriks, Jordi Remón · 2024 · American Society of Clinical Oncology Educational Book
- Triple combination therapy comprising osimertinib, an AXL inhibitor, and an FGFR inhibitor improves the efficacy of EGFR-mutated non-small cell lung cancerRyota Nakamura, Tadaaki Yamada, Shinsaku Tokuda, Kenji Morimoto, Yuki Katayama, Yohei Matsui, Soichi Hirai, Masaki Ishida, Hayato Kawachi, Ryo Sawada et al. · 2024 · Cancer Letters
- Observational Study of Treatment Patterns in Patients with Epidermal Growth Factor Receptor (EGFR) Mutation-Positive Non-Small Cell Lung Cancer After First-Line EGFR-Tyrosine Kinase InhibitorsEric Nadler, Melissa Pavilack, Janet L. Espirito, Jamyia Clark, Ancilla W. Fernandes · 2020 · Advances in Therapy
- RET Fusion: Joining the Ranks of Targetable Molecular Drivers in NSCLCBadi Edmond El Osta, Suresh S. Ramalingam · 2020 · JTO Clinical and Research Reports
- Ubiquitin ligase SMURF2 enhances epidermal growth factor receptor stability and tyrosine-kinase inhibitor resistanceParamita Ray, Krishnan Raghunathan, Aarif Ahsan, Uday Sankar Allam, Shirish Shukla, Venkatesha Basrur, Sarah L. Veatch, Theodore Steven Lawrence, Mukesh Kumar Nyati, Dipankar Ray · 2020 · Journal of Biological Chemistry
- Detection of Tumor-Associated Membrane Receptors on Extracellular Vesicles from Non-Small Cell Lung Cancer Patients via Immuno-PCRChristiane Stiller, Kristina Viktorsson, Elizabeth Paz Gomero, Petra Hååg, Vasiliki Arapi, Vitaliy O. Kaminskyy, Caroline Kamali, Luigi De Petris, Simon Ekman, Rolf Lewensohn et al. · 2021 · Cancers
- Chinese Herbal Medicine Combined With First-Generation EGFR-TKIs in Treatment of Advanced Non-Small Cell Lung Cancer With EGFR Sensitizing Mutation: A Systematic Review and Meta-AnalysisYan Lu, Chenbing Sun, Lijing Jiao, Yu Liu, Yabin Gong, Ling Xu · 2021 · Frontiers in Pharmacology
- Concurrent use of aspirin with osimertinib is associated with improved survival in advanced EGFR-mutant non-small cell lung cancerLiu, Xiaoke, Hong, Lingzhi, Nilsson, Monique, Hubert, Shawna Marie, Wu, Shuhong, Rinsurongkawong, Waree, Lewis, Jeffery, Spelman, Amy, Roth, Jack, Swisher, Steven et al. · 2020 · Lung Cancer
- Distinct Progression and Efficacy of First-Line Osimertinib Treatment According to Mutation Subtypes in Metastatic NSCLC Harboring EGFR MutationsYuki Takeyasu, Tatsuya Yoshida, Ken Masuda, Yuji Matsumoto, Yuki Shinno, Yusuke Okuma, Yasushi Goto, Hidehito Horinouchi, Noboru Yamamoto, Yuichiro Ohe · 2024 · JTO Clinical and Research Reports
- A Prospective Phase II Trial of First-Line Osimertinib for Patients With EGFR Mutation-Positive NSCLC and Poor Performance Status (OPEN/TORG2040)Tomoya Fukui, Nobuaki Mamesaya, Toshiaki Takahashi, Kazuma Kishi, Takahiro Yoshizawa, Takaaki Tokito, Koichi Azuma, Kei Morikawa, Satoshi Igawa, Yusuke Okuma et al. · 2025 · Journal of Thoracic Oncology
- Strategies to Overcome Resistance to Osimertinib in EGFR-Mutated Lung CancerDonatella Romaniello, Alessandra Morselli, Ilaria Marrocco · 2025 · International Journal of Molecular Sciences
- Simultaneous quantitative detection of afatinib, erlotinib, gefitinib, icotinib, osimertinib and their metabolites in plasma samples of patients with non-small cell lung cancer using liquid chromatography-tandem mass spectrometryXin Xiong, Yuanyuan Zhang, Ziyu Wang, Congya Zhou, Ping Yang, Xin Du, Li Yang, Wei Liu · 2022 · Clinica Chimica Acta
- Modeling the Cost-Effectiveness of Adjuvant Osimertinib for Patients with Resected EGFR-mutant Non-Small Cell Lung CancerChristopher A. Lemmon, Emily Craig Zabor, Nathan A. Pennell · 2022 · The Oncologist
- Targeted Therapy for Older Patients with Non-Small Cell Lung Cancer: Systematic Review and Guidelines from the French Society of Geriatric Oncology (SoFOG) and the French-Language Society of Pulmonology (SPLF)/French-Language Oncology Group (GOLF)Laurent Greillier, Manon Gauvrit, Éléna Paillaud, Nicolas Girard, Coline Montégut, Rabia Boulahssass, Marie Wislez, Frédéric Pamoukdjian, R. Corre, Mathilde Cabart et al. · 2022 · Cancers
- Cardiovascular Risks with Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors and Monoclonal Antibody TherapyKalyan R. Chitturi, Ethan Alexander Burns, Ibrahim N. Muhsen, Kartik Anand, Barry H. Trachtenberg · 2022 · Current Oncology Reports
- Risk Stratification Using a Novel Nomogram for 2190 EGFR-Mutant NSCLC Patients Receiving the First or Second Generation EGFR-TKIJohn Wen‐Cheng Chang, Chen‐Yang Huang, Yueh‐Fu Fang, Ching‐Fu Chang, Cheng‐Ta Yang, Chih‐Hsi S. Kuo, Ping‐Chih Hsu, Chiao‐En Wu · 2022 · Cancers
- Molecular target therapeutics of EGF-TKI and downstream signaling pathways in non-small cell lung cancersChao-Yu Liu, Heng-Fu Lin, Wei-Yi Lai, Yi-Ying Lin, Tzu-Wei Lin, Yi-Ping Yang, Fu-Ting Tsai, Chia-Lin Wang, Yung-Hung Luo, Yuh-Min Chen et al. · 2022 · Journal of the Chinese Medical Association
- Efficacy of immune checkpoint inhibitors in EGFR-Mutant NSCLC patients with EGFR-TKI resistance: A systematic review and meta-analysisXiaoyu Qian, Xiaodan Guo, Ting Li, Wei Hu, Lin Zhang, Caisheng Wu, Feng Ye · 2022 · Frontiers in Pharmacology
- And Still They Come Over Troubled Waters: Can Asia’s Third-Generation EGFR Tyrosine Kinase Inhibitors (Furmonertinib, Aumolertinib, Rezivertinib, Limertinib, Befotertinib, SH-1028, and Lazertinib) Affect Global Treatment of EGFR+ NSCLCSally C. M. Lau, Sai‐Hong Ignatius Ou · 2022 · Journal of Thoracic Oncology
- Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral CenterCamilla Nero, Simona Duranti, Flavia Giacomini, Angelo Minucci, Luciano Giacò, Alessia Piermattei, Maurizio Genuardi, Tina Pasciuto, Andrea Urbani, Gennaro Daniele et al. · 2022 · Journal of Personalized Medicine
- Epidermal growth factor receptor tyrosine kinase inhibitors for non‐small cell lung cancer harboring uncommon EGFR mutations: Real‐world data from TaiwanJohn Wen‐Cheng Chang, Chen‐Yang Huang, Yueh‐Fu Fang, Ching‐Fu Chang, Cheng‐Ta Yang, Chih‐Hsi S. Kuo, Ping‐Chih Hsu, Chiao‐En Wu · 2022 · Thoracic Cancer
- Extended Survival in Patients With Non–Small-Cell Lung Cancer–Associated Brain Metastases in the Modern EraAssaf Berger, Reed Mullen, Kenneth Bernstein, Juan Diego Alzate, Joshua Seth Silverman, Erik P. Sulman, Bernadine R. Donahue, Abraham Chachoua, Elaine Shum, Vamsidhar Velcheti et al. · 2023 · Neurosurgery
- Progress and challenges in RET-targeted cancer therapyXueqing Hu, Ujjwol Khatri, Tao Shen, Jie Wu · 2023 · Frontiers of Medicine
- Propionate reinforces epithelial identity and reduces aggressiveness of lung carcinomaVignesh Ramesh, Paradesi Naidu Gollavilli, Luisa Pinna, Aarif Siddiqui, Adriana Martinez-Turtos, Francesca Napoli, Yasmin Antonelli, Aldo Leal‐Egaña, Jesper Foged Havelund, Simon T. Jakobsen et al. · 2023 · EMBO Molecular Medicine
- Immunotherapy in patients with brain metastasis: advances and challenges for the treatment and the application of circulating biomarkersElena Brozos-Vázquez, C. Rodríguez-López, A. Cortegoso-Mosquera, S. López-Landrove, Laura Muinelo‐Romay, Jorge García, Rafael López‐López, Luis León‐Mateos · 2023 · Frontiers in Immunology
- Discovery of a Novel Potent EGFR Inhibitor Against EGFR Activating Mutations and On-Target Resistance in NSCLCEun Ji Lee, Seung Yeon Oh, You Won Lee, Ju Young Kim, Min-Je Kim, Tae Ho Kim, Jii Bum Lee, Min Hee Hong, Sun Min Lim, Anke Baum et al. · 2024 · Clinical Cancer Research
- The cost-effectiveness of including liquid biopsy into molecular profiling strategies for newly diagnosed advanced non-squamous non-small cell lung cancer in an Asian populationSibo Liu, Nicholas Graves, Aaron C. Tan · 2024 · Lung Cancer
- Exploring the structural activity relationship of the Osimertinib: A covalent inhibitor of double mutant EGFRL858R/T790M tyrosine kinase for the treatment of Non-Small Cell Lung Cancer (NSCLC)Bhatu R. Patil, Kunal Bhadane, Iqrar Ahmad, Yogesh Agrawal, Amit A. Shimpi, Mayur S. Dhangar, Harun Patel · 2024 · Bioorganic & Medicinal Chemistry
- Non-small-cell lung cancer brain metastases and PD-(L)1 immune checkpoint inhibitorsFabrice Barlési, Pascale Tomasini · 2020 · The Lancet Oncology
- Efficacy of immunotherapy in KRAS -mutant non-small-cell lung cancer with comutationsAlexander P. Davis, Wendy A. Cooper, Michael Joseph Boyer, Jenny Lee, Nick Pavlakis, Steven Kao · 2021 · Immunotherapy
- A Novel Third-generation EGFR Tyrosine Kinase Inhibitor Abivertinib for EGFR T790M-mutant Non–Small Cell Lung Cancer: a Multicenter Phase I/II StudyQing Zhou, Lin Wu, Pei Hu, Tongtong An, Jianying Zhou, Li Zhang, Xiao-Qing Liu, Feng Luo, Xin Zheng, Ying Cheng et al. · 2021 · Clinical Cancer Research
- Elevated expression of miR-494-3p is associated with resistance to osimertinib in EGFR T790M-positive non-small cell lung cancerDominika Kaźmierczak, Inger Johanne Zwicky Eide, Radosveta Gencheva, Yi Chun Lai, Rolf Lewensohn, Georgios Tsakonas, Oscar Grundberg, Luigi De Petris, Marc McGowan, Odd Terje Brustugun et al. · 2022 · Translational Lung Cancer Research
- Cardiac Events and Survival in Patients With EGFR-Mutant Non–Small Cell Lung Cancer Treated With OsimertinibChien‐Yu Lin, Wei-Ting Chang, Po‐Lan Su, Chin‐Wei Kuo, J.C. Yang, Chien‐Chung Lin, Sheng-Hsiang Lin · 2024 · JAMA Network Open
- Lazertinib Versus Osimertinib in Previously Untreated EGFR-Mutant Advanced NSCLC: A Randomized, Double-Blind, Exploratory Analysis From MARIPOSASe-Hoon Lee, Shun Lü, Hidetoshi Hayashi, Enriqueta Felip, Alexander I. Spira, Nicolas Girard, Yu Jung Kim, Yurii Ostapenko, Pongwut Danchaivijitr, Baogang Liu et al. · 2025 · Journal of Thoracic Oncology
- Unresectable stage III non-small-cell lung cancer: state of the art and challengesJordi Remón, Antonin Lévy, Romane Gille, Isabelle Martel‐Lafay, Martina Bortolot, Lizza E.L. Hendriks, Corinne Faivre Finn, Natasha B. Leighl, Martin Reck, Maurice Pérol · 2025 · Nature Reviews Clinical Oncology
- SHP2 inhibition enhances the anticancer effect of Osimertinib in EGFR T790M mutant lung adenocarcinoma by blocking CXCL8 loop mediated stemnessLeiming Xia, Fan Yang, Xiao Qin Wu, Suzhi Li, Chen Kan, Hong Zheng, Siying Wang · 2021 · Cancer Cell International
- Feasibility and effectiveness of afatinib for poor performance status patients with EGFR-mutation-positive non-small-cell lung cancer: a retrospective cohort studyChiao‐En Wu, Ching‐Fu Chang, Chen‐Yang Huang, Cheng‐Ta Yang, Chih‐Hsi S. Kuo, Ping‐Chih Hsu, John Wen‐Cheng Chang · 2021 · BMC Cancer
- Molecular subtypes of small cell lung cancer transformed from adenocarcinoma after EGFR tyrosine kinase inhibitor treatmentSoohyun Hwang, Tae Hee Hong, Sehhoon Park, Hyun Ae Jung, Jong‐Mu Sun, Jin Seok Ahn, Myung‐Ju Ahn, Keunchil Park, Yoon‐La Choi, Se‐Hoon Lee · 2021 · Translational Lung Cancer Research
- Gefitinib plus tremelimumab combination in refractory non-small cell lung cancer patients harbouring EGFR mutations: The GEFTREM phase I trialMariona Riudavets, Marie Naigeon, Matthieu Texier, Miriam Dorta, Fabrice Barlési, Julien Mazières, Andrea Varga, Lydie Cassard, Lisa Boselli, Jonathan Grivel et al. · 2021 · Lung Cancer
- Real‐world treatment patterns of metastatic non‐small cell lung cancer patients receiving epidermal growth factor receptor tyrosine kinase inhibitorsRahul A. Shenolikar, Sizhu Liu, Anne Shah, Jenny Y. M. Tse, Yao Cao, Aimee M. Near · 2022 · Cancer Medicine
- Prognostic communication about lung cancer in the precision oncology era: A multiple‐perspective qualitative studyLaura A. Petrillo, Sophia Shimer, Ashley Z. Zhou, Robert K. Sommer, Jill Feldman, Kelly E. Hsu, Joseph Andrew Greer, Lara N. Traeger, Jennifer S. Temel · 2022 · Cancer
- Novel anilinopyrimidine derivatives as potential EGFRT790M/C797S Inhibitors: Design, Synthesis, biological activity studyYanliang Guo, Biao Gao, Peng Gao, Lei Fang, Shaohua Gou · 2022 · Bioorganic & Medicinal Chemistry
- Nazartinib for treatment-naive EGFR-mutant non−small cell lung cancer: Results of a phase 2, single-arm, open-label studyDaniel S.W. Tan, Sang‐We Kim, Santiago Ponce-Aix, Lecia Van Dam Sequist, Egbert Frederik Smit, James Chih‐Hsin Yang, Toyoaki Hida, Ryo Toyozawa, Enriqueta Felip, Juergen Wolf et al. · 2022 · European Journal of Cancer
- Cost-effectiveness of osimertinib versus standard EGFR-TKI as first-line treatment for EGFR-mutated advanced non-small-cell lung cancer in ChinaYamin Shu, Yufeng Ding, Xucheng He, Yanxin Liu, Pan Wu, Qilin Zhang · 2022 · Frontiers in Pharmacology
- EGFR mutation prevalence, real-world treatment patterns, and outcomes among patients with resected, early-stage, non-small cell lung cancer in CanadaM. Sara Kuruvilla, Geoffrey Liu, Iqra A. Syed, Femida hussein Gwadry-Sridhar, Brandon S. Sheffield, Robin Sachdeva, Alec Pencz, Luna Jia Zhan, Katrina Hueniken, Devalben Patel et al. · 2022 · Lung Cancer
- Therapeutic potential for P2Y2 receptor antagonismKimberly J. Jasmer, Kevin Muñoz Forti, Lucas T. Woods, Seunghee Cha, Gary A. Weisman · 2022 · Purinergic Signalling
- CBX5 loss drives EGFR inhibitor resistance and results in therapeutically actionable vulnerabilities in lung cancerSuresh Bugide, Yvonne J. K. Edwards, Romi Gupta, Michael R. Green, Narendra Wajapeyee · 2023 · Proceedings of the National Academy of Sciences
- Clinical Relevance of Targeted Therapy and Immune-Checkpoint Inhibition in Lung CancerGian Marco Leone, Saverio Candido, Alessandro Lavoro, Silvia Vivarelli, Giuseppe Gattuso, Daniela Cornelia Călina, Massimo Libra, Luca Falzone · 2023 · Pharmaceutics
- Indole Antitumor Agents in Nanotechnology Formulations: An OverviewEleonora Russo, Carola Grondona, Chiara Brullo, Andrea Spallarossa, Carla Villa, Bruno Tasso · 2023 · Pharmaceutics
- Efficacy, safety and pharmacokinetics of Unecritinib (TQ-B3101) for patients with ROS1 positive advanced non-small cell lung cancer: a Phase I/II TrialShun Lü, Hongming Pan, Lin Wu, Yu Yao, Jianxing He, Yan Wang, Xiuwen Wang, Yong Fang, Zhen Xian Zhou, Xicheng Wang et al. · 2023 · Signal Transduction and Targeted Therapy
- Targeted therapies in non-small cell lung cancer: present and futureJessica McLaughlin, Jonathan David Berkman, Patrick S. Nana-Sinkam · 2023 · Faculty Reviews
- Patterns of progression on first line osimertinib in patients with EGFR mutation-positive advanced non-small cell lung cancer (NSCLC): A Swiss cohort studyA. Schuler, J. Huser, Sabine Schmid, Sämi Schär, Amina Scherz, Oliver Pascal Gautschi, Laetitia Arja Mauti, Thomas von Briel, Christine Waibel, Luciano Wannesson et al. · 2023 · Lung Cancer
- Machine learning-based radiomics strategy for prediction of acquired EGFR T790M mutation following treatment with EGFR-TKI in NSCLCJiameng Lu, Xiaoqing Ji, Xinyi Liu, Yunxiu Jiang, Gang Li, Ping Fang, Wei Li, Anli Zuo, Zihan Guo, Shuran Yang et al. · 2024 · Scientific Reports
- Evolving Precision First-Line Systemic Treatment for Patients with Unresectable Non-Small Cell Lung CancerTianhong Li, Weijie Ma, Ebaa Al-Obeidi · 2024 · Cancers
- Advances in Personalized OncologyHiba Mechahougui, James Gutmans, Gina Colarusso, Roumaïssa Gouasmi, Alex Friedlaender · 2024 · Cancers
- First-line zorifertinib for EGFR-mutant non-small cell lung cancer with central nervous system metastases: The phase 3 EVEREST trialQing Hua Zhou, Yan Yu, Ligang Xing, Ying Cheng, Ying Wang, Yueyin Pan, Yun Fan, Jianhua Shi, Guojun Zhang, Jiuwei Cui et al. · 2024 · Med
- Four generations of EGFR TKIs associated with different pathogenic mutations in non-small cell lung carcinomaRui Li, Xiaofei Zhou, Hong-Juan Yao, Liang Li · 2020 · Journal of drug targeting
- Impact of neutrophil-to-lymphocyte ratio in patients with EGFR-mutant NSCLC treated with tyrosine kinase inhibitorsTaihei Ono, Satoshi Igawa, Shintaro Kurahayashi, Yuriko Okuma, Ai Sugimoto, Seiichiro Kusuhara, Takahiro Ozawa, Tomoya Fukui, Jiichiro Sasaki, Hisashi Mitsufuji et al. · 2020 · Investigational New Drugs
- Chemotherapy Plus EGFR-TKI as First-Line Treatment Provides Better Survival for Advanced EGFR-Positive Lung Adenocarcinoma Patients: Updated Data and Exploratory In Vitro StudyYuqing Lou, Jianlin Xu, Yanwei Zhang, Jun Lü, Tianqing Chu, Xueyan Zhang, Huimin Wang, Hua Zhong, Wei Zhang, Baohui Han · 2020 · Targeted Oncology
- Heterogeneous Response to First-Generation Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancers with Different EGFR Exon 19 MutationsHaiyan Xu, Weihua Li, Guangjian Yang, Junling Li, Lu Yang, Fei Xu, Yaning Yang, Jianming Ying, Yan Wang · 2020 · Targeted Oncology
- Adult precision medicine: learning from the past to enhance the futureAshley Parham Ghiaseddin, Lan Hoang-Minh, Michalina Janiszewska, David H. Shin, Wolfgang Wick, Duane A. Mitchell, Patrick Yung Wen, Stuart A. Grossman · 2020 · Neuro-Oncology Advances
- New lung-cancer drugs extend survival timesMichael S. Eisenstein · 2020 · Nature
- Almonertinib-induced interstitial lung diseaseTing Jiang, Yiyang Luo, Binbin Wang · 2021 · Medicine
- Identification of SLC38A7 as a Prognostic Marker and Potential Therapeutic Target of Lung Squamous Cell CarcinomaNaoki Haratake, Qingjiang Hu, Tatsuro Okamoto, Tomoko Jogo, Gouji Toyokawa, Fumihiko Kinoshita, Tomoyoshi Takenaka, Tetsuzo Tagawa, Norifumi Iseda, Shinji Itoh et al. · 2021 · Annals of Surgery
- Prognostic influence of epidermal growth factor receptor mutation and radiological ground glass appearance in patients with early-stage lung adenocarcinomaKeiju Aokage, Tomohiro Miyoshi, Masashi Wakabayashi, Takashi Ikeno, Jun Suzuki, Kenta Tane, Joji Samejima, Masahiro Tsuboi · 2021 · Lung Cancer
- Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR -mutant lung cancerPınar Ö. Eser, Raymond M. Paranal, Jieun Son, Elena V. Ivanova, Yanan Kuang, Heidi M. Haikala, Ciric To, Jeffrey J. Okoro, Kshiti H. Dholakia, Jihyun Choi et al. · 2021 · Science Translational Medicine
- LPCAT1 promotes gefitinib resistance via upregulation of the EGFR/PI3K/AKT signaling pathway in lung adenocarcinomaJianghua Ding, Xinjing Ding, Zhaohui Leng · 2022 · Journal of Cancer
- Comparison of next‐generation sequencing and cobas EGFR mutation test v2 in detecting EGFR mutationsShuji Murakami, Tomoyuki Yokose, Kanako Shinada, Testuya Isaka, Kengo Katakura, Ryouta Ushio, Tetsuro Kondo, Terufumi Kato, Hiroyuki Ito, Haruhiro Saito · 2022 · Thoracic Cancer
- Patients with non‑small cell lung cancer with the exon 21 L858R mutation: From distinct mechanisms to epidermal growth factor receptor tyrosine kinase inhibitor treatments (Review)Jiayu Liu, Shouzheng Wang, Hanqi Yuan, Junling Li, Puyuan Xing · 2024 · Oncology Letters
- Comprehensive PTM profiling with SCASP-PTM uncovers mechanisms of p62 degradation and ALDOA-mediated tumor progressionZhan-Peng Lin, Guohong Gan, Xiao Xu, Chengwen Wen, Xin Ding, Xiangyu Chen, Kaijie Zhang, Wenyu Guo, Mingxin Lin, Yu-Yang Wang et al. · 2025 · Cell Reports
- Osimertinib plus consolidative radiotherapy for advanced EGFR mutant non–small cell lung cancer: a multicentre, single-arm, phase 2 trialSagus Sampath, Sawsan Rashdan, Puneeth Iyengar, Townes A Mickel, Song Zhang, Chul Woo Ahn, Ang Gao, Jonathan E. Dowell, Yuanyuan Zhang, Kenneth D. Westover et al. · 2025 · EClinicalMedicine
- The International Association for the Study of Lung Cancer Staging Project: The Impact of Common Molecular Alterations on Overall Survival in NSCLC in Initial Analyses of the IASLC Ninth Edition Staging DatabaseDavid Paul Carbone, Fred R Hirsch, Raymond Uyiosa Osarogiagbon, Katherine K. Nishimura, Ming‐Sound Tsao, William David Travis, Dawei Yang, Soo‐Ryum Yang, Yasushi Yatabe, Luiz Henrique Araujo et al. · 2025 · Journal of Thoracic Oncology
- The Comprehensive Analyses of Genomic Variations and Assessment of TMB and PD-L1 Expression in Chinese Lung Adenosquamous CarcinomaYong Cheng, Yanxiang Zhang, Yuwei Yuan, Jiao Wang, Ke Liu, Bin Yu, Li Xie, Chao Ou-Yang, Lin Wu, Xiaoqun Ye · 2021 · Frontiers in Genetics
- Rare cancer, rare alteration: the case of NTRK fusions in biliary tract cancersAlice Boilève, Loïc Verlingue, Antoine Hollebecque, Valérie Boige, Michel Pierre Ducreux, David Malka · 2021 · Expert Opinion on Investigational Drugs
- Feasibility and Challenges for Sequential Treatments in ALK-Rearranged Non-Small-Cell Lung CancerMei Elsayed, Farastuk Bozorgmehr, Daniel N. Kazdal, Anna‐Lena Volckmar, Holger Sültmann, Jürgen R. Fischer, Mark Kriegsmann, Albrecht Stenzinger, Michael Thomas, Petros Christopoulos · 2021 · Frontiers in Oncology
- Budget Impact Analysis of Comprehensive Genomic Profiling in Patients With Advanced Non–Small-Cell Lung CancerMichael J. Harvey, Rachel Cunningham, Bethany Sawchyn, Meagan Montesion, Prasanth Reddy, Ali McBride, Anita Chawla · 2021 · JCO Precision Oncology
- Durable Response to Combined Osimertinib and Pralsetinib Treatment for Osimertinib Resistance Due to Novel IntergenicANK3-RETFusion inEGFR-Mutated Non–Small-Cell Lung CancerEdyta Maria Urbanska, Jens Benn Sørensen, Linea Cecilie Melchior, Junia Cardoso Costa, Eric Santoni‐Rugiu · 2022 · JCO Precision Oncology
- Retrospective analysis of independent predictors of progression‐free survival in patients with EGFR mutation‐positive advanced non‐small cell lung cancer receiving first‐line osimertinibShuhei Teranishi, Chihiro Sugimoto, Satoshi Nagaoka, Hirokazu Nagayama, Wataru Segawa, Atsushi Miyasaka, Shuntaro Hiro, Yukihito Kajita, Chihiro Maeda, Nobuaki Kobayashi et al. · 2022 · Thoracic Cancer
- Quality of Life and Cognitive Function Evaluations and Interventions for Patients with Brain Metastases in the Radiation Oncology ClinicJennifer K. Matsui, Haley Kopp Perlow, Cyril Baiyee, Alex R. Ritter, Mark Vikas Mishra, Joseph A. Bovi, Vinai Gondi, Paul D. Brown, Ashlee R. Loughan, Heather E. Leeper et al. · 2022 · Cancers
- EGFR inhibition in EGFR ‐mutant lung cancer cells perturbs innate immune signaling pathways in the tumor microenvironmentAkihiko Shiiya, Takuro Noguchi, Utano Tomaru, Shin Ariga, Yuta Takashima, Yoshihito Ohhara, Jun Taguchi, Satoshi Takeuchi, Yasushi Shimizu, Ichiro Kinoshita et al. · 2022 · Cancer Science
- Navigating patient journey in early diagnosis of lung cancer in IndiaBivas Biswas, Deepak Talwar, Priti Lokesh Meshram, Pramod K Julka, Anurag Mehta, S. P. Somashekhar, Srinivas C. Chilukuri, Abhishek Bansal · 2022 · Lung India
- Personalized treatment for patients with lung cancerMartin Schüler, Servet Bölükbas, Kaid Darwiche, Dirk Theegarten, Ken Herrmann, Martin Stuschke · 2023 · Deutsches Ärzteblatt international
- Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future directionsJia Zhong, Hua Bai, Zhijie Wang, Jianchun Duan, Wei Zhuang, Di Wang, Rui Wan, Jiachen Xu, Kailun Fei, Zixiao Ma et al. · 2023 · Frontiers of Medicine
- Taking early preventive interventions to manage the challenging issue of acquired resistance to third-generation EGFR inhibitorsShi‐Yong Sun · 2023 · Chinese Medical Journal - Pulmonary and Critical Care Medicine
- Abnormal activation of NF‐κB and MAPK signaling pathways affect osimertinib resistance and influence the recruitment of myeloid‐derived suppressor cells to shape the immunosuppressive tumor immune microenvironmentChao Wang, Kailun Fei, Lihui Liu, Jianchun Duan, Zhijie Wang, Sini Li, Jiachen Xu, Xue Zhang, Yanhua Tian, Yan Qu et al. · 2023 · Thoracic Cancer
- Discovery of YK-029A, a novel mutant EGFR inhibitor targeting both T790 M and exon 20 insertion mutations, as a treatment for NSCLCBin Liu, Feng Gao, Hui Zhao, Shuai Yuan, Xingzhe Peng, Pengzhi Zhang, Jing Wang, Tongmei Zhang, Maosheng Duan, Yongqi Guo · 2023 · European Journal of Medicinal Chemistry
- The Health Inequality Impact of Liquid Biopsy to Inform First-Line Treatment of Advanced Non–Small Cell Lung Cancer: A Distributional Cost-Effectiveness AnalysisJeroen Paul Jansen, Meera Vimala Ragavan, Cheng Chen, Michael P. Douglas, Kathryn A. Phillips · 2023 · Value in Health
- The development of amivantamab for the treatment of non-small cell lung cancerDanielle Brazel, Misako Nagasaka · 2023 · Respiratory Research
- Natural Product-Based Glycolysis Inhibitors as a Therapeutic Strategy for Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung CancerWonyoung Park, Jung Ho Han, Shibo Wei, Eun-Sun Yang, Se-Yun Cheon, Sung‐Jin Bae, Dongryeol Ryu, Hwan‐Suck Chung, Ki‐Tae Ha · 2024 · International Journal of Molecular Sciences
- A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive non-small cell lung cancer: OSCILLATELavinia Tan, Chris S. B. Brown, Antony J. Mersiades, Chee Khoon Lee, Thomas John, Steven Kao, Genni M Newnham, Kenneth John O'Byrne, Sagun Parakh, Victoria Bray et al. · 2024 · Nature Communications
- Treatment outcomes and prognostic factors in patients with driver mutant non-small cell lung cancer and de novo brain metastasesSeda Kahraman, Serdar Karakaya, Kaplan Ma, Sema Sezgin Göksu, Akın Öztürk, Zehra Sucuoğlu İşleyen, Jamshid Hamdard, Sedat Yildirim, Tolga Doğan, Selver Işık et al. · 2024 · Scientific Reports
- Targeting the MET-Signaling Pathway in Non-Small–Cell Lung Cancer: Evidence to DateOlivier Bylicki, Nicolas Paleiron, Jean‐Baptiste Assié, CHRISTOS CHOUAID · 2020 · OncoTargets and Therapy
- Neoadjuvant treatment of stage IIIA-N2 in EGFR-Mutant/ALK-rearranged non-small cell lung cancerRoxana Reyes, Noemı́ Reguart · 2021 · Translational Lung Cancer Research
- Clinical Benefit of Tyrosine Kinase Inhibitors in Advanced Lung Cancer with EGFR-G719A and Other Uncommon EGFR MutationsKartik Sehgal, Deepa Rangachari, Paul A. VanderLaan, Susumu S. Kobayashi, Daniel Botelho Costa · 2020 · The Oncologist