The DOI matches its Crossref record.
Minimal Residual Disease in Chronic Myeloid Leukemia
Abstract
For many years hematologists have used the microscope to identify a complete remission of leukemia after treatment with chemotherapy. In a hematologic complete remission, we know that a large portion of the leukemic cells remain out of sight. These cells, invisible to the microscopist, are the components of an important clinical problem termed “minimal residual disease.”The concept of minimal residual disease and its detection and eradication were the topic of a special series of conferences held in Rotterdam, the Netherlands, in 1983 and subsequent years. In those days, we were beginning to see a substantial number of patients with . . .
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“However, molecular remissions in response to Imatinib are not uniform and kinase domain mutations have been identified that are resistant to Imatinib therapy (Gorre et al., 2002;Lowenberg, 2003).”
From Rac Guanosine Triphosphatases Represent Integrating Molecular Therapeutic Targets for BCR-ABL-Induced Myeloproliferative Disease (2007) · cites this paper as Lowenberg, 2003
Citations
Cited by
Thomas, E. K., Cancelas, J. A., Chae, H.-D., Cox, A. D., Keller, P. J., Perrotti, D., Neviani, P., Druker, B. J., Setchell, K. D. R., Zheng, Y., et al. (2007) · Cancer Cell · doi:10.1016/j.ccr.2007.10.015 · Cited by 147
Metadata
- Authors
- Löwenberg, B.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2003-10-09
- Volume
- 349
- Issue
- 15
- Pages
- 1399-1401
- ISSN
- 0028-4793
- 1533-4406
- Cited by
- 44
- References
- 0
- Language
- en
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- CoChat. (2026). Citation check: Minimal Residual Disease in Chronic Myeloid Leukemia. https://app.cochat.ai/papers/10.1056/nejmp038130
- The paper
- Löwenberg, B. (2003). Minimal Residual Disease in Chronic Myeloid Leukemia. New England Journal of Medicine. https://doi.org/10.1056/nejmp038130
