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Cited by 655

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Direct Thrombin Inhibitors

Open access
Di Nisio, Marcello, Middeldorp, Saskia, Büller, Harry R.·2005·New England Journal of Medicine

Abstract

Direct thrombin inhibitors (DTIs) are a new class of anticoagulants that bind directly to thrombin and block its interaction with its substrates. Four parenteral DTIs have been approved by the FDA — hirudin and argatroban for heparin-induced thrombocytopenia, bivalirudin as an alternative to heparin in percutaneous coronary intervention, and desirudin as prophylaxis against venous thromboembolism in hip replacement. This article discusses the clinical data on this important new class of medications.

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Registry

Crossref · 10.1056/nejmra044440

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Citations

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Cited by

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Metadata

Authors
Di Nisio, M., Middeldorp, S., & Büller, H. R.
Venue
New England Journal of Medicine
Published
2005-09-08
Volume
353
Issue
10
Pages
1028-1040
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2012761317
Cited by
655
References
1
FWCI
30.59
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Direct Thrombin Inhibitors. https://app.cochat.ai/papers/10.1056/nejmra044440
The paper
Di Nisio, M., Middeldorp, S., & Büller, H. R. (2005). Direct Thrombin Inhibitors. New England Journal of Medicine. https://doi.org/10.1056/nejmra044440

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.