The Tuberous Sclerosis Complex

Mutation and cancer: statistical study of retinoblastoma

Knudson, A. G. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.4.820 · Cited by 7,612

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Inoki, K., Zhu, T., & Guan, K.-L. (2003) · Cell · doi:10.1016/s0092-8674(03)00929-2 · Cited by 3,914

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Inoki, K., Li, Y., Xu, T., & Guan, K.-L. (2003) · Genes & Development · doi:10.1101/gad.1110003 · Cited by 1,911

Identification of the Tuberous Sclerosis Gene TSC1 on Chromosome 9q34

Slegtenhorst, M. V., Hoogt, R. D., Hermans, C., Nellist, M., Janssen, B., Verhoef, S., Lindhout, D., Ouweland, A. V. D., Halley, D., Young, J., et al. (1997) · Science · doi:10.1126/science.277.5327.805 · Cited by 1,648

Identification and characterization of the tuberous sclerosis gene on chromosome 16

(1993) · Cell · doi:10.1016/0092-8674(93)90618-z · Cited by 1,645

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

Manning, B. D., Tee, A. R., Logsdon, M. N., Blenis, J., & Cantley, L. C. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00568-3 · Cited by 1,555

Phosphorylation and Functional Inactivation of TSC2 by Erk

Ma, L., Chen, Z., Erdjument-Bromage, H., Tempst, P., & Pandolfi, P. P. (2005) · Cell · doi:10.1016/j.cell.2005.02.031 · Cited by 1,268

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

Fingar, D. C., & Blenis, J. (2004) · Oncogene · doi:10.1038/sj.onc.1207542 · Cited by 1,264

The LKB1 tumor suppressor negatively regulates mTOR signaling

Shaw, R. J., Bardeesy, N. M., Manning, B. D., Lopez, L. V., Kosmatka, M., DePinho, R. A., & Cantley, L. C. (2004) · Cancer Cell · doi:10.1016/j.ccr.2004.06.007 · Cited by 1,107

Potential of Capric Acid in Neurological Disorders: An Overview

Shekhar, N., Tyagi, S., Rani, S., & Thakur, A. K. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03809-4 · Cited by 20

The Burden of Subependymal Giant Cell Astrocytomas Associated With Tuberous Sclerosis Complex

Skalicky, A. M., Rentz, A. M., Liu, Z., Wheless, J. W., Pelletier, C. L., Dunn, D. W., Frost, M., Nakagawa, J., Magestro, M., Prestifilippo, J., et al. (2014) · Journal of Child Neurology · doi:10.1177/0883073814523318 · Cited by 18

Glioblastoma multiforme in a child with tuberous sclerosis complex

Vignoli, A., Lesma, E. A., Alfano, R. M., Peron, A., Scornavacca, G. F., Massimino, M., Schiavello, E., Ancona, S., Cerati, M., Bulfamante, G., et al. (2015) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.37158 · Cited by 18

The International LAM Registry: A Component of an Innovative Web-Based Clinician, Researcher, and Patient-Driven Rare Disease Research Platform

Nurok, M., Eslick, I. S., de Carvalho, C. R. R., Costabel, U., D'Armiento, J. M., Glanville, A. R., Harari, S. A., Henske, E. P., Inoue, Y., Johnson, S. R., et al. (2010) · Lymphatic Research and Biology · doi:10.1089/lrb.2009.0028 · Cited by 18

Towards an improved understanding of TSC-Associated Neuropsychiatric Disorders (TAND)

Leclezio, L., & de Vries, P. (2016) · Advances in Autism · doi:10.1108/aia-12-2015-0025 · Cited by 17

Early manifestations of renal disease in patients with tuberous sclerosis complex

Málaga-Diéguez, L., Spencer, R., Pehrson, L. J., Vento, S., Menzer, K., Devinsky, O., & Trachtman, H. (2017) · International Journal of Nephrology and Renovascular Disease · doi:10.2147/ijnrd.s123638 · Cited by 18

microRNA 92b-3p regulates primordial follicle assembly by targeting TSC1 in neonatal mouse ovaries

Li, T., Liu, X., Gong, X., Qiukai, E., Zhang, X., & Zhang, X. (2019) · Cell Cycle · doi:10.1080/15384101.2019.1593648 · Cited by 18

Mutations of the MAPK/TSC/mTOR pathway characterize periventricular glioblastoma with epithelioid SEGA-like morphology-morphological and therapeutic implications

Georgescu, M.-M., Li, Y., Islam, M. Z., Notarianni, C., Sun, H., Olar, A., & Fuller, G. N. (2019) · Oncotarget · doi:10.18632/oncotarget.27005 · Cited by 18

Neuroendocrine Tumor of the Pancreas in a Patient With Tuberous Sclerosis

Díaz, D. D., Ibarrola, C., Sanz, R., Pérez, B., Tabares, J. S., & Ruizdelgado, F. C. (2011) · International Journal of Surgical Pathology · doi:10.1177/1066896911428735 · Cited by 18

Hippocampal Abnormalities in an MR Imaging Series of Patients with Tuberous Sclerosis

Gama, H. P. P., da Rocha, A. J., Valerio, R. M. F., da Silva, C. J., & Garcia, L. Á. L. (2010) · American Journal of Neuroradiology · doi:10.3174/ajnr.a1972 · Cited by 18

Inherited renal carcinomas

Kawashima, A., Young, S. W., Takahashi, N., King, B. F., & Atwell, T. D. (2016) · Abdominal Radiology · doi:10.1007/s00261-016-0743-6 · Cited by 18

Observational study of characteristics and clinical outcomes of Dutch patients with tuberous sclerosis complex and renal angiomyolipoma treated with everolimus

Zonnenberg, B. A., Neary, M. P., Duh, M. S., Ionescu‐Ittu, R., Fortier, J., & Vekeman, F. (2018) · PLoS ONE · doi:10.1371/journal.pone.0204646 · Cited by 18

Molecular Genetics of Renal Cell Carcinoma: A Narrative Review Focused on Clinical Relevance

Millan, B., Loebach, L., Blachman-Braun, R., Patel, M. H., Saini, J., Linehan, W. M., & Ball, M. W. (2025) · Current Oncology · doi:10.3390/curroncol32060359 · Cited by 20

Precision medicine for metastatic renal cell carcinoma

Sonpavde, G., & Choueiri, T. K. (2013) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2013.07.010 · Cited by 17

Giant Bilateral Renal Angiomyolipomas and Lymphangioleiomyomatosis Presenting after Two Successive Pregnancies Successfully Treated with Surgery and Rapamycin

Peces, R., Cuesta-López, E., Peces, C., & Selgas, R. (2011) · The Scientific World JOURNAL · doi:10.1100/2011/263137 · Cited by 17

Tumor Suppressors TSC1 and TSC2 Differentially Modulate Actin Cytoskeleton and Motility of Mouse Embryonic Fibroblasts

Goncharova, E. A., James, M. L., Kudryashova, T. V., Goncharov, D. A., & Krymskaya, V. P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111476 · Cited by 17

Real-World Evidence Study on the Long-Term Safety of Everolimus in Patients With Tuberous Sclerosis Complex: Final Analysis Results

Rojas, M. L. R.-F., Feucht, M., Macaya, A., Wilken, B., Hahn, A., Maamari, R., Hirschberg, Y., Ridolfi, A., & Kingswood, J. C. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.802334 · Cited by 17

The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth

Schrötter, S., Yuskaitis, C. J., MacArthur, M. R., Mitchell, S. J., Hosios, A. M., Osipovich, M., Torrence, M. E., Mitchell, J. R., Hoxhaj, G., Şahin, M., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110824 · Cited by 19

Subependymal giant-cell astrocytoma: A surgical review in the modern era of mTOR inhibitors

Danassegarane, G., Tinois, J., Sahler, Y., Aouaissia, S., & Riffaud, L. (2022) · Neurochirurgie · doi:10.1016/j.neuchi.2022.07.003 · Cited by 17

Extension of Microglial Activation is Associated with Epilepsy and Cognitive Dysfunction in Tuberous Sclerosis Complex: A Tspo-Pet Study

Kagitani‐Shimono, K., Kato, H., Soeda, F., Iwatani, Y., Mukai, M., Ogawa, K., Tominaga, K., Nabatame, S., & Taniike, M. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103288 · Cited by 17

Arachnoid cysts in tuberous sclerosis complex

Boronat, S., Caruso, P. A., Auladell, M. A., van Eeghen, A. M., & Thiele, E. A. (2013) · Brain and Development · doi:10.1016/j.braindev.2013.11.003 · Cited by 17

Mammalian target of rapamycin complex 1 activation in podocytes promotes cellular crescent formation

Mao, J., Zeng, Z., Xu, Z., Li, J., Jiang, L., Fang, Y., Xu, X., Hu, Z., He, W., Yang, J., et al. (2014) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00018.2014 · Cited by 18

Neurocutaneous syndromes

Kurlemann, G. (2012) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52899-5.00046-0 · Cited by 17

Model‐Informed Drug Development for Everolimus Dosing Selection in Pediatric Infant Patients

Combes, F. P., Einolf, H. J., Coello, N., Heimbach, T., He, H., & Grosch, K. (2020) · CPT Pharmacometrics & Systems Pharmacology · doi:10.1002/psp4.12502 · Cited by 17

Pathogenic variants identified by whole-exome sequencing in 43 patients with epilepsy

Zhang, L., Gao, J., Liu, H., Tian, Y., Zhang, X., Li, Y., Li, Y., Guo, Y., Yuan, E., Yuan, E., et al. (2020) · Human Genomics · doi:10.1186/s40246-020-00294-0 · Cited by 17

Beyond Protein Synthesis; The Multifaceted Roles of Tuberin in Cell Cycle Regulation

da Silva, E. F., Fong, J., Roye‐Azar, A., Nadi, A., Drouillard, C., Pillon, A., & Porter, L. A. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.806521 · Cited by 17

A scoping review on cannabidiol therapy in tuberous sclerosis: Current evidence and perspectives for future development

Samanta, D. (2022) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2022.108577 · Cited by 19

Expression and Cellular Distribution of Vascular Endothelial Growth Factor‐C System in Cortical Tubers of the Tuberous Sclerosis Complex

Zhang, C., Shu, H., Yin, Q., An, N., Xu, S., Yin, J., Song, Y., Liu, S., & Yang, H. (2011) · Brain Pathology · doi:10.1111/j.1750-3639.2011.00519.x · Cited by 17

Similar Trends in Serum VEGF-D Levels and Kidney Angiomyolipoma Responses with Longer Duration Sirolimus Treatment in Adults with Tuberous Sclerosis

Malinowska, I. A., Lee, N. Y., Kumar, V., Thiele, E. A., Franz, D. N., Ashwal, S., Sagalowsky, A. I., DiMario, F. J., Cutler, D., Krueger, D. A., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056199 · Cited by 17

Importancia del tamaño de las tuberosidades en las complicaciones del complejo esclerosis tuberosa

Pascual-Castroviejo, I., Hernández-Moneo, J. L., Pascual, S. I. P., Viano, J. C., Gutiérrez-Molina, M., Velázquez-Fragua, R., Tapia, D. Q., & Bastos, C. M. (2012) · Neurología · doi:10.1016/j.nrl.2012.11.002 · Cited by 17

Seizures and intellectual outcome: Clinico-radiological study of 30 Egyptian cases of tuberous sclerosis complex

Samir, H., Ghaffar, H. A., & Nasr, M. (2010) · European Journal of Paediatric Neurology · doi:10.1016/j.ejpn.2010.07.010 · Cited by 17

Co2/Erbium:YAG/Dye Laser Combination: An Effective and Successful Treatment for Angiofibromas in Tuberous Sclerosis

Fioramonti, P., Santo, L. D., Ruggieri, M., Carella, S., Torto, F. L., Onesti, M. G., & Scuderi, N. (2013) · Aesthetic Plastic Surgery · doi:10.1007/s00266-013-0252-8 · Cited by 17

mTOR

Child, N. D., & Benarroch, E. E. (2014) · Neurology · doi:10.1212/wnl.0000000000000922 · Cited by 17

mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency

Li, H., Jin, F., Jiang, K., Ji, S., Wang, L., Ni, Z., Chen, X., Hu, Z., Zhang, H., Liu, Y., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.8633 · Cited by 17

Recent advances in the pathobiology and clinical management of lymphangioleiomyomatosis

Harari, S. A., Spagnolo, P., Cocconcelli, E., Luisi, F., & Cottin, V. (2018) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000000502 · Cited by 17

Dermatologic manifestations of endocrine disorders

Quatrano, N. A., & Loechner, K. J. (2012) · Current Opinion in Pediatrics · doi:10.1097/mop.0b013e328355a31b · Cited by 17

Viral expression of constitutively active AKT3 induces CST axonal sprouting and regeneration, but also promotes seizures

Campion, T., Sheikh, I. S., Smit, R. D., Iffland, P. H., Chen, J., Junker, I. P., Krynska, B., Crino, P. B., & Smith, G. M. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113961 · Cited by 15

Altered cytokine levels in the cerebrospinal fluid of adult patients with autism spectrum disorder

Runge, K., Fiebich, B. L., Kuzior, H., Rausch, J., Maier, S. J., Dersch, R. S., Nickel, K., Domschke, K., van Elst, L. T., & Endres, D. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.12.032 · Cited by 18

The Dawn of In Vivo Gene Editing Era: A Revolution in the Making

Niazi, S. K. (2023) · Biologics · doi:10.3390/biologics3040014 · Cited by 17

Subependymal nodules and giant cell tumours in tuberous sclerosis complex patients: prevalence on MRI in relation to gene mutation

Michelozzi, C., Leo, G. D., Galli, F., Barbosa, F. S., Labriola, F. S., Sardanelli, F., & Cornalba, G. (2012) · Child s Nervous System · doi:10.1007/s00381-012-1892-8 · Cited by 16

Convergent synaptic and circuit substrates underlying autism genetic risks

McGee, A. W., Li, G., Lu, Z., & Qiu, S. (2014) · Frontiers in Biology · doi:10.1007/s11515-014-1298-y · Cited by 17

Novel mechanism of regulation of fibrosis in kidney tumor with tuberous sclerosis

Liang, S., Cuevas, G., Tizani, S., Salas, T., Liu, H., Li, B., & Habib, S. L. (2013) · Molecular Cancer · doi:10.1186/1476-4598-12-49 · Cited by 16

Arthrogryposes (Multiple Congenital Contractures)

Hall, J. G. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.05632-4 · Cited by 16

Thoracoabdominal imaging of tuberous sclerosis

Morin, C. E., Morin, N. P., Franz, D. N., Krueger, D. A., Trout, A. T., & Towbin, A. J. (2018) · Pediatric Radiology · doi:10.1007/s00247-018-4123-y · Cited by 16

Location-dependent maintenance of intrinsic susceptibility to mTORC1-driven tumorigenesis

Rushing, G. V., Brockman, A. A., Bollig, M. K., Leelatian, N., Mobley, B. C., Irish, J. M., Ess, K. C., Fu, C., & Ihrie, R. A. (2019) · Life Science Alliance · doi:10.26508/lsa.201800218 · Cited by 17

A Review of Investigations for Patients With Tuberous Sclerosis Complex Who Were Referred to the Tuberous Sclerosis Clinic at The Hospital for Sick Children: Identifying Gaps in Surveillance

Alsowat, D., Zak, M., McCoy, B., Kabir, N., Al‐Mehmadi, S., Chan, V. W., & Whitney, R. (2019) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2019.06.018 · Cited by 16

Cortico-Cortical Evoked Potentials in Children With Tuberous Sclerosis Complex Using Stereo-Electroencephalography

Yu, X., Ding, P., Liu, Y., Zhang, J., Liang, S., Zhang, S., Liu, N., & Liang, S. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.01093 · Cited by 16

Bone tissue and mineral metabolism in hereditary endocrine tumors: clinical manifestations and genetic bases

Maraghelli, D., Giusti, F., Marini, F., & Brandi, M. L. (2020) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-020-01380-1 · Cited by 16

Sirolimus relieves seizures and neuropsychiatric symptoms via changes of microglial polarity in tuberous sclerosis complex model mice

Koike-Kumagai, M., Fujimoto, M., & Wataya‐Kaneda, M. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109203 · Cited by 16

Asociación lupus eritematoso sistémico y esclerosis tuberosa, un caso

Cubero, C. C., Moguel, V. B., Gil, M. Á. F., & Vega, J. L. Á. (2015) · Reumatología Clínica · doi:10.1016/j.reuma.2015.08.003 · Cited by 16

Expression of the interleukin 17 in cortical tubers of the tuberous sclerosis complex

He, J., Wu, K., Li, S., Shu, H., Zhang, C., Liu, S., Yang, M., Yin, Q., & Yang, H. (2013) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2013.05.007 · Cited by 16

Lymphangioleiomyomatosis Treatment With Sirolimus

Casanova, Á., Girón, R. M., Acosta, O., Barrón, M., Valenzuela, C., & Ancochea, J. (2011) · Archivos de Bronconeumología · doi:10.1016/j.arbr.2011.01.007 · Cited by 16

Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complex

Feliciano, D. M., Zhang, S., Quon, J. L., & Bordey, A. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt018 · Cited by 16

From man to mouse and back again: advances in defining tumor AKTivities in vivo

Restuccia, D. F., & Hemmings, B. A. (2010) · Disease Models & Mechanisms · doi:10.1242/dmm.004671 · Cited by 16

Characterisation of TSC1 promoter deletions in tuberous sclerosis complex patients

van den Ouweland, A. M. W., Elfferich, P., Zonnenberg, B. A., ARTS, W. F. M., Kleefstra, T., Nellist, M. D., Millán, J. M., Withagen-Hermans, C., Maat‐Kievit, A., & Halley, D. J. J. (2010) · European Journal of Human Genetics · doi:10.1038/ejhg.2010.156 · Cited by 16

Rare familial TSC2 gene mutation associated with atypical phenotype presentation of Tuberous Sclerosis Complex

Fox, J., Ben‐Shachar, S., Uliel‐Sibony, S., Svirsky, R., Saitsu, H., Matsumoto, N., & Fattal‐Valevski, A. (2017) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.38027 · Cited by 16

Rheb in neuronal degeneration, regeneration, and connectivity

Potheraveedu, V. N., Schöpel, M., Stoll, R., & Heumann, R. (2017) · Biological Chemistry · doi:10.1515/hsz-2016-0312 · Cited by 18

Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex

McKenna, J., Kapfhamer, D., Kinchen, J. M., Wasek, B. L., Dunworth, M., Stewart, T. M., Bottiglieri, T., Casero, R. A., & Gambello, M. J. (2018) · Human Molecular Genetics · doi:10.1093/hmg/ddy118 · Cited by 16

Imaging for Screening and Surveillance of Patients with Hereditary Forms of Renal Cell Carcinoma

Freifeld, Y. N., Ananthakrishnan, L., & Margulis, V. (2018) · Current Urology Reports · doi:10.1007/s11934-018-0829-5 · Cited by 16

The Evolution of Subclinical Seizures in Children With Tuberous Sclerosis Complex

de Groen, A.-E. C., Bolton, J. B., Bergin, A. M. R., Şahin, M., & Peters, J. M. (2019) · Journal of Child Neurology · doi:10.1177/0883073819860640 · Cited by 16

Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish

Kim, S., Kowalski, M. L., Carson, R. P., Bridges, L. R., & Ess, K. C. (2013) · Disease Models & Mechanisms · doi:10.1242/dmm.011494 · Cited by 16

Treatment-Resistant Epilepsy and Tuberous Sclerosis Complex: Treatment, Maintenance, and Future Directions

Singh, A., Hadjinicolaou, A., Peters, J. M., & Salussolia, C. L. (2023) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s347327 · Cited by 18

Three-Year Follow-Up after Intrauterine mTOR Inhibitor Administration for Fetus with TSC-Associated Rhabdomyoma

Maász, A., Bodó, T., Till, Á., Molnár, G., Masszi, G., Labossa, G., Herbert, Z., Bene, J., & Hadzsiev, K. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241612886 · Cited by 15

Deciphering the Enigma of Neuron-Glial Interactions in Neurological Disorders

Ahmad, S. R., Zeyaullah, M., AlShahrani, A. M., Dawria, A., Ali, H., Mohieldin, A., Altijani, A. A. G., Razi, U., Mehdi, M., Akram, S., et al. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2904142 · Cited by 15

Prognostic Significance of mTOR and PTEN in Patients with Esophageal Squamous Cell Carcinoma

Lu, J., Pan, Y., Xia, X., Gu, Y., & Lei, Y.-Y. (2015) · BioMed Research International · doi:10.1155/2015/417210 · Cited by 15

Visual Evoked Potentials as a Readout of Cortical Function in Infants With Tuberous Sclerosis Complex

Varcin, K. J., Nelson, C. A., Ko, J. A., Şahin, M., Wu, J. Y., & Jeste, S. (2015) · Journal of Child Neurology · doi:10.1177/0883073815587328 · Cited by 17

TSC1 Controls Distribution of Actin Fibers through Its Effect on Function of Rho Family of Small GTPases and Regulates Cell Migration and Polarity

Ohsawa, M., Kobayashi, T., Okura, H., Igarashi, T., Mizuguchi, M., & Hino, O. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054503 · Cited by 15

Nursing Implications for the Lifelong Management of Tuberous Sclerosis Complex

Agricola, K. D., Tudor, C., Krueger, D. A., & Franz, D. N. (2013) · Journal of Neuroscience Nursing · doi:10.1097/jnn.0b013e3182986146 · Cited by 15

Percutaneous cryoablation for tuberous sclerosis-associated renal angiomyolipoma with neoadjuvant mTOR inhibition

Krummel, T., Garnon, J., Lang, H., Gangi, A., & Hannedouche, T. P. (2014) · BMC Urology · doi:10.1186/1471-2490-14-77 · Cited by 15

Targeting the mTOR Pathway in Tumor Malignancy

Cheng, H., Walls, M., Baxi, S. M., & Yin, M.-J. (2013) · Current Cancer Drug Targets · doi:10.2174/1568009611313030005 · Cited by 15

Real-Time Monitoring of Tumorigenesis, Dissemination, & Drug Response in a Preclinical Model of Lymphangioleiomyomatosis/Tuberous Sclerosis Complex

Liu, F., Lunsford, E. P., Tong, J., Ashitate, Y., Gibbs, S. L., Yu, J. J., Choi, H. S., Henske, E. P., & Frangioni, J. V. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038589 · Cited by 15

Diagnosis and Management of Hereditary Renal Cell Cancer

Menko, F. H., & Maher, E. R. (2016) · Recent results in cancer research/Recent Results in Cancer Research · doi:10.1007/978-3-319-29998-3_6 · Cited by 17

mTORC1 Inhibition Is an Effective Treatment for Sporadic Renal Angiomyolipoma

Pleniceanu, O., Omer, D., Azaria, E., Harari‐Steinberg, O., & Dekel, B. (2017) · Kidney International Reports · doi:10.1016/j.ekir.2017.07.016 · Cited by 15

Molecular Characterization and Putative Pathogenic Pathways of Tuberous Sclerosis Complex–Associated Renal Cell Carcinoma

Park, J. H., Lee, C., Chang, M. S., Kim, K., Choi, S., Lee, H., Lee, H., & Moon, K. C. (2018) · Translational Oncology · doi:10.1016/j.tranon.2018.05.010 · Cited by 15

Congenital Lymphatic Malformation and Aortic Aneurysm in a Patient with TSC2 Mutation

Wiemer‐Kruel, A., Mayer, H., Ewert, P., Martinoff, S. A., Eckstein, H., Kriebel, T. A., Bissler, J. J., Franz, D. N., & Bast, T. (2019) · Neuropediatrics · doi:10.1055/s-0039-1694985 · Cited by 15

A case of subependymal giant cell astrocytoma without tuberous sclerosis complex and review of the literature

O’Rawe, M., Chandran, A. S., Joshi, S., Simonin, A., Dyke, J. M., & Lee, S. C. L. (2020) · Child s Nervous System · doi:10.1007/s00381-020-04823-z · Cited by 15

Clinical management of tuberous sclerosis complex over the lifetime of a patient

Frost, M., & Hulbert, J. C. (2015) · Pediatric Health Medicine and Therapeutics · doi:10.2147/phmt.s67342 · Cited by 15

Coil embolization of an intracranial aneurysm in an infant with tuberous sclerosis complex: A case report and literature review

Deshaies, E., Yi, J., Galgano, M., & Spinoza, Z. T. (2012) · Surgical Neurology International · doi:10.4103/2152-7806.102944 · Cited by 15

Response of Subependymal Giant Cell Astrocytoma With Spinal Cord Metastasis to Everolimus

Aguilera, D. G., Flamini, R. J., Mazewski, C., Schniederjan, M., Hayes, L. L., Boydston, W. R., Castellino, R. C., & MacDonald, T. J. (2013) · Journal of Pediatric Hematology/Oncology · doi:10.1097/mph.0000000000000005 · Cited by 14

Conservation of Structural and Functional Elements of TSC1 and TSC2: A Bioinformatic Comparison Across Animal Models

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