Electrolyte Disturbances in Patients with Chronic Alcohol-Use Disorder
Abstract
Electrolyte disturbances are common among patients with chronic alcohol-use disorder. This review discusses these disturbances and focuses on the interrelationship between the physiological features of the relevant electrolyte disorders and approaches to therapy.
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Hypoglycemia was found in approximately 25% of patients with alcohol use disorder presenting with alcoholic ketoacidosis.
“Hypoglycemia was found in ~25% of patients with alcohol use disorder presenting with alcoholic ketoacidosis [16].”
From Non-Diabetic Hypoglycemia: Evaluation and Management in Adults (2025) · cites this paper as [16]
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Dhatariya, K. K., Glaser, N. S., Codner, E., & Umpierrez, G. E. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-0165-1 · Cited by 461 · see citing works
Non-Diabetic Hypoglycemia: Evaluation and Management in Adults
Looi, E., & Lawler, H. M. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14134393 · Cited by 10 · see citing works
“Hypoglycemia was found in ~25% of patients with alcohol use disorder presenting with alcoholic ketoacidosis [16].”
Lin, Y.-Y., & Hsieh, Y.-S. (2021) · Cureus · doi:10.7759/cureus.15880 · Cited by 6 · see citing works
- Authors
- Palmer, B. F., & Clegg, D. J.
- Affiliations
- Cedars-Sinai Medical Center (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2017-10-05
- Volume
- 377
- Issue
- 14
- Pages
- 1368-1377
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2762837562
- Cited by
- 111
- References
- 0
- Citations by year
- 2026: 9 · 2025: 8 · 2024: 12 · 2023: 19 · 2022: 17 · 2021: 14 · 2020: 17 · 2019: 10 · 2018: 3 · 2017: 1 · 2016: 1
- FWCI
- 1.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Alcoholism and Thiamine Deficiency
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Electrolyte and hormonal disorders
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Keywords
- electrolyte imbalance, alcoholism, electrolyte therapy, alcohol withdrawal
- MeSH terms
- Acid-Base Imbalance, Alcoholism, Humans, Hyponatremia, Ketosis, Water-Electrolyte Imbalance
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