Molecular Genetic Investigations of Personality: From Candidate Genes to Genome-wide Associations
Abstract
Temperament is traditionally defined as a dynamic feature of human mental activity such as its rates, rhythm and intensity. Psychologists differentiate temperament and character traits and consider temperament traits as heritable ones manifesting early in ontogenesis, while character traits represent values and goals formed during an individual’s development and socio-cultural learning (Van Gestel & Van Broeckhoven, 2003). The study of personality traits as dynamic characteristics of human behaviour originates from Hippocrates (V-IV cent. BC) and Galen (II cent. BC), who characterized the main types of the human behaviour. To date, multiple theories and concepts of personality exist reflecting hypothesized biological correlates including central nervous system functioning. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Differences in allele and genotype frequencies between ethnic groups can change SNPs' effect.
“One of the possible limitations of using PGS for predicting ASB is the ethnic origin of the examined population, since differences in allele and genotype frequencies between ethnic groups can change SNPs’ effect (Kazantseva et al., 2016).”
From Using polygenic scores to assess liability to antisocial behavior (2025) · cites this paper as Kazantseva et al., 2016
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References 179 · Cited by 2
- Authors
- Kazantseva, A., Malykh, S., & Khusnutdinova, E.
- Affiliations
- Russian Academy of Education (RU)
- Venue
- Behavioural Genetics for Education
- Publisher
- Palgrave Macmillan UK
- Published
- 2016
- Pages
- 130-154
- OpenAlex
- W2414079888
- Cited by
- 2
- References
- 179
- Citations by year
- 2025: 1 · 2021: 1
- FWCI
- 0.00
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Palgrave Macmillan UK eBooks (publishedVersion)
- Funders
- Russian Foundation for Basic Research
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- personality, temperament, character traits, heritability, candidate genes, genome-wide association study, personality theory, central nervous system
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