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Nonlinear scanning laser microscopy by third harmonic generation
Abstract
Third harmonic generation near the focal point of a tightly focused beam is used to probe microscopical structures of transparent samples. It is shown that this method can resolve interfaces and inhomogeneities with axial resolution comparable to the confocal length of the beam. Using 120 fs pulses at 1.5 μm, we were able to resolve interfaces with a resolution of 1.2 μm. Two-dimensional cross-sectional images have also been produced.
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Cited by
In vivo three-photon microscopy of subcortical structures within an intact mouse brain
Horton, N. G., Wang, K., Kobat, D., Clark, C. G., Wise, F. W., Schaffer, C. B., & Xu, C. (2013) · Nature Photonics · doi:10.1038/nphoton.2012.336 · Cited by 1,505
Coherent Anti-Stokes Raman Scattering Microscopy: Instrumentation, Theory, and Applications
Cheng, J.-X., & Xie, X. S. (2004) · The Journal of Physical Chemistry B · doi:10.1021/jp035693v · Cited by 963
Laser-Scanning Coherent Anti-Stokes Raman Scattering Microscopy and Applications to Cell Biology
Cheng, J.-X., Jia, Y. K., Zheng, G., & Xie, X. S. (2002) · Biophysical Journal · doi:10.1016/s0006-3495(02)75186-2 · Cited by 371
Metadata
- Authors
- Barad, Y., Eisenberg, H., Horowitz, M., & Silberberg, Y.
- Venue
- Applied Physics Letters
- Publisher
- AIP Publishing
- Published
- 1997-02-24
- Volume
- 70
- Issue
- 8
- Pages
- 922-924
- ISSN
- 0003-6951 (ISSN-L)
- 1077-3118
- OpenAlex
- W1965229287
- Cited by
- 607
- References
- 0
- FWCI
- 7.22
- Type
- journal article
- Language
- en
- Open access
- closed
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: Nonlinear scanning laser microscopy by third harmonic generation. https://app.cochat.ai/papers/10.1063/1.118442
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- Barad, Y., Eisenberg, H., Horowitz, M., & Silberberg, Y. (1997). Nonlinear scanning laser microscopy by third harmonic generation. Applied Physics Letters. https://doi.org/10.1063/1.118442
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
