The DOI matches its Crossref record; 18 of the 19 references it cites were found in a registry or an index.
Childhood vulvar lichen sclerosus: An increasingly common problem
Abstract
Background Lichen sclerosus (LS) of the vulva in children is presenting more commonly, but its origin is unknown.Objective The purpose of this study was to assess the prevalence of childhood vulvar LS, to examine factors that may play a role in its cause, and to attempt to define the current optimal treatment.Methods We surveyed 70 cases of LS currently being treated in the pediatric vulvar clinic to collect information on presentation, family history, associated disease, and typical course of the disorder. We looked retrospectively and prospectively at treatments for LS.Results We found a prevalence of premenarchal LS of 1 in 900 and confirmed an increasing incidence. In a high proportion of cases (77%), the question of sexual abuse had been raised. A family history of LS was found in a minimum of 17% of cases. Associated autoimmune disease occurred in 14%, but 64% told of a family history, and atopy occurred in 59%. Potent topical steroid ointments appear to alleviate symptoms most effectively, with minimal side effects.Conclusion Although the cause of LS remains uncertain, it is not a rare disease in prepubertal girls. Current optimal management includes prompt diagnosis and institution of treatment with a potent topical steroid.
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Metadata
- Authors
- Powell, J., & Wojnarowska, F.
- Affiliations
- John Radcliffe Hospital (GB)
- Venue
- Journal of the American Academy of Dermatology
- Publisher
- Elsevier BV
- Published
- 2001-05
- Volume
- 44
- Issue
- 5
- Pages
- 803-806
- ISSN
- 0190-9622 (ISSN-L)
- OpenAlex
- W2069570115
- Cited by
- 274
- References
- 19
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 17 · 2023: 11 · 2022: 10 · 2021: 20 · 2020: 15 · 2019: 12 · 2018: 6 · 2017: 12 · 2016: 14 · 2015: 13 · 2014: 13 · 2013: 11 · 2012: 11
- FWCI
- 10.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Academy of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Genital Health and Disease
- Health Sciences › Dentistry › General Dentistry › Oral Health Pathology and Treatment
- Health Sciences › Medicine › Dermatology › Genetic and rare skin diseases.
- Keywords
- lichen sclerosus, vulvar lichen sclerosus, pediatric vulvar disease, prevalence, incidence, sexual abuse, family history (medicine), autoimmune disease, atopy, topical corticosteroids
- MeSH terms
- Adolescent, Child, Child, Preschool, England, Female, Humans, Risk Factors, Vulvar Diseases, Cohort Studies, Incidence, Prevalence, Lichen Sclerosus et Atrophicus
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