Cited by 81Temporomandibular Joint DisordersMusculoskeletal pain and rehabilitationOrthodontics and Dentofacial Orthopedics

Randomized clinical trial of primary treatment for temporomandibular joint disk displacement without reduction and without osseous changes: A combination of NSAIDs and mouth-opening exercise versus no treatment

Yuasa, Hidemichi, Kurita, Kenichi·2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

Abstract

Objective The effectiveness of nonsteroidal anti-inflammatory drugs (NSAIDs) and physical therapy for disk displacement without reduction is unknown. This study compared this treatment method with nontreatment controls. Methods Sixty patients with painful disk displacement without reduction and without osseous changes were randomly divided in 2 groups, consisting of NSAID and physical therapy and a nontreated control group. Both groups were observed at 2 weeks and, for those patients who did not show any improvement, again at 4 weeks. Results There was 60% improvement in the treatment group compared with 33% in the control group during the entire 4 weeks of the study. The number needed to treat for benefit was 3.75, with a 95% CI 2.103 to 65.935. Conclusions A combination of NSAID and physical therapy for 4 weeks is effective as a primary treatment of patients with disk displacement without reduction and without osseous changes.

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Crossref · 10.1067/moe.2001.114005

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Authors
Yuasa, H., & Kurita, K.
Affiliations
Aichi Gakuin University (JP)
Venue
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
Publisher
Elsevier BV
Published
2001-06
Volume
91
Issue
6
Pages
671-675
ISSN
1079-2104 (ISSN-L)
OpenAlex
W2055348340
Cited by
81
References
0
Citations by year
2026: 1 · 2025: 2 · 2024: 2 · 2023: 3 · 2022: 4 · 2021: 1 · 2020: 8 · 2019: 2 · 2018: 2 · 2017: 4 · 2016: 4 · 2015: 6 · 2014: 6 · 2013: 3 · 2012: 3
FWCI
4.99
Type
journal article
Language
en
Open access
closed
Locations
  • Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Health Sciences › Dentistry › Orthodontics › Orthodontics and Dentofacial Orthopedics
Keywords
temporomandibular disorders, disk displacement without reduction, nonsteroidal anti-inflammatory drugs, mouth opening exercises, physiotherapy, primary treatment, treatment effectiveness, number needed to treat
MeSH terms
Adolescent, Adult, Age Factors, Anti-Inflammatory Agents, Non-Steroidal, Joint Dislocations, Exercise Therapy, Facial Pain, Female, Follow-Up Studies, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Prodrugs, Statistics as Topic, Thiazines, Confidence Intervals, Range of Motion, Articular, Treatment Outcome, Sample Size, Statistics, Nonparametric, Temporomandibular Joint Disc

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