The DOI matches its Crossref record; 26 of the 28 references it cites were found in a registry or an index.
Long-term results after early primary repair of tetralogy of Fallot.
Open accessAbstract
Objective Early primary repair of tetralogy of Fallot has been routinely performed at Children's Hospital, Boston, since 1972. We evaluated the long-term outcome of this treatment strategy including the influence of a transannular patch.Methods Fifty-seven patients less than 24 months of age (median 8 months) underwent primary repair of tetralogy of Fallot between January 1972 and December 1977. Thirty-one patients had a transannular patch. Survival and freedom from reintervention were determined by the Kaplan-Meier method with 95% confidence intervals.Results There were 8 early deaths, and 1 patient died 24 years after initial repair. Recent follow-up was obtained for 45 of the 49 long-term survivors (92%). Median follow-up was 23.5 years. Ten patients underwent reintervention, 8 of whom underwent relief of right ventricular outflow tract obstruction. Right ventricular outflow tract obstruction occurred in 6 patients without a transannular patch and 2 with a transannular patch (33% vs 6%, P =.04). One pulmonary valve replacement was performed at another institution 20 years after the repair. Forty-one long-term survivors were in New York Heart Association class I and 4 were in class II. Actuarial survival was 86% at 20 years (95% confidence intervals = 80%-92%). Freedom from reintervention was 93% at 5 years (95% confidence intervals = 87%-99%) and 79% at 20 years (95% confidence intervals = 70%-86%). No significant differences were found between patients with and without a transannular patch (survival, P =.34; freedom from reintervention, P =.09, log-rank tests).Conclusions Long-term survival is excellent and the freedom from reintervention is satisfactory after early primary repair of tetralogy of Fallot in the 1970s. Use of a transannular patch does not reduce late survival and is associated with a lower incidence of right ventricular outflow tract obstruction.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source doesn’t support the claim as written.
In the citing paper
“The risk-benefit balance of VS procedures compared with TAP remains unclear in this setting even if studies3,16,17,18,19,20 based on multicenter surgical registries found increased survival and decreased reintervention rates among patients who underwent a VS procedure compared with those who underwent TAP.”
From Comparison of Long-term Outcomes of Valve-Sparing and Transannular Patch Procedures for Correction of Tetralogy of Fallot (2021) · cites this paper as [20]
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Many studies found no difference in survival comparing TAP and VS procedures,11,18,20,32,33,34,36,37,38,40”
From Comparison of Long-term Outcomes of Valve-Sparing and Transannular Patch Procedures for Correction of Tetralogy of Fallot (2021) · cites this paper as [20]
The cited source says what the claim attributes to it.
In the citing paper
“Most previous single center studies did not find a difference in the risk of reintervention comparing surgical procedures for correction of TOF.18,20,32,38,40”
From Comparison of Long-term Outcomes of Valve-Sparing and Transannular Patch Procedures for Correction of Tetralogy of Fallot (2021) · cites this paper as [20]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1992) · Springer series in statistics · doi:10.1007/978-1-4612-4380-9_25 · Cited by 45,239
Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1958) · Journal of the American Statistical Association · doi:10.1080/01621459.1958.10501452 · Cited by 39,158
Long-term outcome in patients undergoing surgical repair of tetralogy of Fallot
Murphy, J. G., Gersh, B. J., Mair, D. D., Fuster, V., McGoon, M. D., Ilstrup, D. M., McGoon, D. C., Kirklin, J. W., & Danielson, G. K. (1993) · New England Journal of Medicine · doi:10.1056/nejm199308263290901 · Cited by 998
Reoperation in adults with repair of tetralogy of Fallot: indications and outcomes.
Oechslin, E. N., Harrison, D. A., Harris, L., Downar, E., Webb, G. D., Siu, S. S., & Williams, W. G. (1999) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(99)70214-x · Cited by 264
Carvalho, J. S., Shinebourne, E. A., Busst, C., Rigby, M. L., & Redington, A. N. (1992) · Heart · doi:10.1136/hrt.67.6.470 · Cited by 262
Repair of tetralogy of Fallot in infancy
Castañeda, A. R., Freed, M. D., Williams, R. G., & Norwood, W. I. (1977) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(19)41351-2 · Cited by 225
Neonatal repair of tetralogy of Fallot with and without pulmonary atresia
Donato, R. M. D., Jonas, R. A., Lang, P., Rome, J. J., Mayer, J. E., & Castañeda, A. R. (1991) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(19)36802-3 · Cited by 178
Self-citationEffect of transannular patching on outcome after repair of tetralogy of Fallot
Kirklin, J. K., Kirklin, J. W., Blackstone, E. H., Milano, A., & Pacifico, A. D. (1989) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(89)90671-1 · Cited by 175
The First Open Heart Corrections of Tetralogy of Fallot: A 26–31 Year Follow-up of 106 Patients
LILLEHEI, C. W., VARCO, R. L., COHEN, M., WARDEN, H. E., GOTT, V. L., DEWALL, R. A., PATTON, C., & MOLLER, J. H. (1986) · Annals of Surgery · doi:10.1097/00000658-198610000-00017 · Cited by 168
Flagged first, then by citations
2 of the 28 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 201–240 of 240
LaPar, D. J., & BACHA, E. A. (2020) · Springer eBooks · doi:10.1007/978-3-030-24174-2_101 · Cited by 1
Self-citationHoffman, F. J. I. E. (2009) · Wiley eBooks · doi:10.1002/9781444314045.ch41 · Cited by 1
Der Kardiologie von morgen auf der Spur
Maisch, B., & Drexler, H. (2009) · Herz · doi:10.1007/s00059-009-3224-7 · Cited by 1
Congenital Heart Disease and Anomalies of the Great Vessels
Devaney, E. J., Ohye, R. G., & Bove, E. L. (2006) · Elsevier eBooks · doi:10.1016/b978-0-323-02842-4.50126-1 · Cited by 1
Dodge‐Khatami, A., Chen, P., & Mavroudis, C. D. (2023) · Wiley eBooks · doi:10.1002/9781119282327.ch21 · Cited by 1
Giamberti, A. (2012) · Springer eBooks · doi:10.1007/978-88-470-2358-1_13
Angeborene Herzfehler mit Anomalien des rechtsventrikulären Ausflusstrakts
Ziemer, G., & Nagy, Z. (2010) · Springer eBooks · doi:10.1007/978-3-540-79713-5_13
7.25 Cardiac Patch with Cells: Biological or Synthetic
Akhyari, P., Barth, M., & Lichtenberg, A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-100691-7.00157-9
Other Transcatheter Procedures
Chessa, M., & Butera, G. (2012) · Springer eBooks · doi:10.1007/978-88-470-2358-1_11
TETRALOGY OF FALLOT: REPORT OF TWO CASES IN OUTPATIENT PRACTICE
Đorđević, G., & Grujić-Ilić, G. (2016)
Late results after paediatric cardiac surgery
Nieminen, H. P. (2009) · Työväentutkimus Vuosikirja
Hraška, V., & Muríň, P. (2012) · Springer eBooks · doi:10.1007/978-3-642-24169-7_4
Arslan, Ö., Adademir, T., Elibol, A., Uğur, O., Kalender, M., Aydemir, N. A., & Thoracic, S. E. (2013)
Ferna Fallots á Íslandi 1968-2001
Eiríksson, H., & Helgason, H. (2004) · Hirsla (Landspítali University Hospital)
Perioperative Right Ventricular Management
Ranucci, M. (2012) · Springer eBooks · doi:10.1007/978-88-470-2358-1_15
Rompel, O., Janka, R., Glöckler, M., Cesnjevar, R. A., Dittrich, S., Lell, M., Uder, M., & Hammon, M. (2015)
Valvulation pulmonaire percutanée
Malekzadeh-Milani, S. G., & Boudjemline, Y. (2015) · doi:10.1016/s1166-4568(15)66487-7
Postoperative Residua and Sequelae
Inai, K. (2017) · Springer eBooks · doi:10.1007/978-981-10-4542-4_3
Congenital Heart Disease with Anomalies of the Right Ventricular Outflow Tract
Ziemer, G., & Kaulitz, R. (2017) · Springer eBooks · doi:10.1007/978-3-662-52672-9_15
Imaging Modalities—Magnetic Resonance Imaging and Computed Tomography
Gaur, L., Morin, C. E., Morin, N. P., & Spevak, P. J. (2018) · Elsevier eBooks · doi:10.1016/b978-1-4557-0760-7.00036-x
Critical Care Management of the Adult with Tetralogy of Fallot
Isgrò, G., Ranucci, M., & Chessa, M. (2018) · Congenital heart disease in adolescents and adults · doi:10.1007/978-3-319-94171-4_10
Complex assessment of complications in operated patients with Fallot's tetrad at the hospital stage
Mekenbayeva, R., Sarsembayeva, A., Adilbekova, A., Vakpayev, D., Mekenbayeva, N., & Akseitov, A. (2019) · Journal of Clinical Medicine of Kazakhstan · doi:10.23950/1812-2892-jcmk-00685
Cardiac Patch with Cells: Biological or Synthetic
Akhyari, P., Barth, M., & Lichtenberg, A. (2011) · Comprehensive Biomaterials · doi:10.1016/b978-0-08-055294-1.00225-7
Kareem, F. A., & Mohsin, H. (2020) · Mustansiriya Medical Journal · doi:10.4103/mj.mj_9_19
Tetralogy of Fallot: Late Outcome
Weil, J. (2012) · Springer eBooks · doi:10.1007/978-88-470-2358-1_6
Pinto, F. F. (2017) · Revista Portuguesa de Cardiologia (English Edition) · doi:10.1016/j.repce.2016.12.005
Magnetic Resonance Imaging Evaluation of Complex Congenital Heart Disease
Prakash, A., & Geva, T. (2019) · Contemporary cardiology · doi:10.1007/978-1-4939-8841-9_19
Long-term Outcomes of Tetralogy of Fallot in the Kingdom of Bahrain
Agarwal, A., Amer, S. R. A., Tarif, H. A., Ismael, A. A., Alshaiji, A. F., Arulselvam, V., & Kalis, N. N. (2022) · Heart Views · doi:10.4103/heartviews.heartviews_77_21
(2022) · Haug Verlag in Georg Thieme Verlag KG eBooks · doi:10.1055/b-0042-192110
The Adult with Tetralogy of Fallot
Isgrò, G., Giamberti, A., Ranucci, M., Foresti, S., & Chessa, M. (2023) · Springer eBooks · doi:10.1007/978-1-4471-4999-6_185-2
Joosen, R. S., Voskuil, M., Krasemann, T., Blom, N. A., Krings, G. J., & Breur, J. M. P. J. (2024) · Trials · doi:10.1186/s13063-024-08436-8
Erdil, T., Steigmiller, K., Rampa, J. E., Christmann, M., Held, U., & Dave, H. H. (2024) · Swiss Medical Weekly · doi:10.57187/s.3689
Tariq, J., Ansari, A. S., Mistry, A. A., Abbas, Q., Ahmad, W., Amanullah, M. M., Malik, M., & Mohsin, S. S. (2025) · Pediatric Cardiology · doi:10.1007/s00246-025-03813-9
Surgical treatment of infants with severe form of tetralogy of Fallot
Morsina, M. G., Voitov, A. V., Arkhipov, A. N., Bogachev-Prokophiev, A. V., & Soynov, I. A. (2025) · Russian Journal of Cardiology and Cardiovascular Surgery · doi:10.17116/kardio202518041445
Complications Associated with Repair of Tetralogy of Fallot
Mavroudis, C. D. (2025) · Springer eBooks · doi:10.1007/978-3-032-02661-3_12 · Cited by 1
Tailored Interventions for Adults with Congenital Heart Defects: A Modern Perspective
Varrica, A., Frigiola, A., Țăruș, A., & Giamberti, A. (2026) · Springer eBooks · doi:10.1007/978-3-032-16676-0_12
Bhat, M., Malm, T. K., Nordenstam, F., Hanséus, K., Rosenkvist, C.-J., & Liuba, P. (2026) · Pediatric Cardiology · doi:10.1007/s00246-026-04283-3
Pediatric and Congenital Heart Disease
Campbell, M. J., Powell, A. J., & Valente, A. M. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-12497-6.00042-7
Maiti, A., & Guha, A. (2026) · Annals of Cardiac Anaesthesia · doi:10.4103/aca.aca_333_25
Metadata
- Authors
- Bacha, E. A., Scheule, A. M., Zurakowski, D., Erickson, L. C., Hung, J., Lang, P., Mayer, J. E., del Nido, P. J., & Jonas, R. A.
- Affiliations
- Boston Children's Hospital (US)
- Venue
- The Journal of Thoracic and Cardiovascular Surgery
- Publisher
- Elsevier BV
- Published
- 2001-07
- Volume
- 122
- Issue
- 1
- Pages
- 154-161
- ISSN
- 0022-5223 (ISSN-L)
- OpenAlex
- W2155350077
- Cited by
- 240
- References
- 28
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 6 · 2023: 5 · 2022: 5 · 2021: 7 · 2020: 14 · 2019: 10 · 2018: 17 · 2017: 14 · 2016: 16 · 2015: 11 · 2014: 16 · 2013: 18 · 2012: 17
- FWCI
- 2.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Thoracic and Cardiovascular Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Cardiovascular Conditions and Treatments
- Keywords
- tetralogy of Fallot, transannular patch, long-term survival, reintervention, right ventricular outflow tract obstruction, pulmonary valve replacement, infants, congenital heart surgery
- MeSH terms
- Female, Humans, Infant, Male, Reoperation, Retrospective Studies, Tetralogy of Fallot, Proportional Hazards Models, Treatment Outcome, Exercise Tolerance, Prostheses and Implants
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
