The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Elevated blood pressure and decreased cognitive function among school-age children and adolescents in the United States
Abstract
Objective To evaluate the relationship between elevated blood pressure (BP) and cognitive test performance in a nationally representative sample of children. Study design The National Health and Nutrition Examination Survey III provides cross-sectional data for children 6 to 16 years, including BP and cognitive test scores. Elevated BP was defined as systolic or diastolic BP >or=90th percentile. Cognitive tests were compared for children with elevated and normal BP. Linear regression was used to evaluate the relation between elevated BP and decreased test scores. Results Among the 5077 children, 3.4% had systolic BP >or=90th percentile and 1.6% diastolic BP >or=90th percentile. Children with elevated systolic BP had lower average scores compared with normotensive children for digit span (7.9 vs 8.7, P=.01), block design (8.6 vs 9.5, P=.03), and mathematics (89.6 vs 93.8, P=.01). Elevated diastolic BP was associated with lower average scores on block design (9.5 vs 11, P=.01). Linear regression showed that elevated systolic BP was independently associated with lower digit span scores (P=.032). Conclusion Children with elevation of systolic BP are at risk for central nervous system end-organ damage, as manifested by decreased digit span test scores.
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“Conversely, low academic achievement is strongly associated with risk-taking behavior, compromised health status, and reduced longevity.22–33”
From School-Based Health Centers to Advance Health Equity (2016) · cites this paper as [22]
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Cites
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Update: Ambulatory Blood Pressure Monitoring in Children and Adolescents
Flynn, J. T., Daniels, S. R., Hayman, L. L., Maahs, D. M., McCrindle, B. W., Mitsnefes, M. M., Zachariah, J. P. V., & Urbina, E. M. (2014) · Hypertension · doi:10.1161/hyp.0000000000000007 · Cited by 608
“Furthermore, hypertension may also have neurovascular consequences, because untreated hypertensive children had lower cerebral artery reactivity than normotensive control subjects,(35) which may explain the lower scores on cognitive tests found in children with elevated BP.(36) ABPM may be superior to casual (office)…”
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Yates, K. F., Sweat, V., Yau, P. L., Turchiano, M. M., & Convit, A. (2012) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.112.252759 · Cited by 444
Design and Methods of the Chronic Kidney Disease in Children (CKiD) Prospective Cohort Study
Furth, S. L., Cole, S. R., Moxey‐Mims, M., Kaskel, F. J., MAK, R. H. K., Schwartz, G. J., Wong, C. S., Tilde]oz, A. M., & Warady, B. A. (2006) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.01941205 · Cited by 407
“The effects of CKD on neurodevelopment and cognitive function of children remain largely unknown, but age of CKD onset (42,43), duration of kidney failure (44,45), hypertension (46), anemia (47–50), and depression (51–53) have been associated with impairments in cognition and neurodevelopment.”
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Metadata
- Authors
- Lande, M. B., Kaczorowski, J. M., Auinger, P., Schwartz, G. J., & Weitzman, M.
- Affiliations
- University of Rochester Medicine (US)
- Corresponding author
- Lande, Marc B
- Venue
- The Journal of Pediatrics
- Publisher
- Elsevier BV
- Published
- 2003-12
- Volume
- 143
- Issue
- 6
- Pages
- 720-724
- ISSN
- 0022-3476 (ISSN-L)
- OpenAlex
- W2081457754
- Cited by
- 197
- References
- 23
- Citations by year
- 2026: 5 · 2025: 1 · 2024: 7 · 2023: 5 · 2022: 11 · 2021: 8 · 2020: 7 · 2019: 9 · 2018: 11 · 2017: 7 · 2016: 12 · 2015: 11 · 2014: 14 · 2013: 17 · 2012: 18
- FWCI
- 3.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Pediatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- elevated blood pressure, pediatric hypertension, cognitive function, systolic blood pressure, diastolic blood pressure, digit span, block designs, mathematics achievement, elementary school students, adolescents
- MeSH terms
- Adolescent, Blood Pressure, Child, Cognition Disorders, Cross-Sectional Studies, Female, Humans, Hypertension, Male, Neuropsychological Tests, Nutrition Surveys, United States
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