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Rare earth-doped glass microbarcodes
Open accessAbstract
The development of ultraminiaturized identification tags has applications in fields ranging from advanced biotechnology to security. This paper describes micrometer-sized glass barcodes containing a pattern of different fluorescent materials that are easily identified by using a UV lamp and an optical microscope. A model DNA hybridization assay using these “microbarcodes” is described. Rare earth-doped glasses were chosen because of their narrow emission bands, high quantum efficiencies, noninterference with common fluorescent labels, and inertness to most organic and aqueous solvents. These properties and the large number (>1 million) of possible combinations of these microbarcodes make them attractive for use in multiplexed bioassays and general encoding.
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Cited by
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Nie, S., Xing, Y., Kim, G. J., & Simons, J. W. (2007) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.9.060906.152025 · Cited by 952
Physical unclonable functions generated through chemical methods for anti-counterfeiting
Arppe, R., & Sørensen, T. J. (2017) · Nature Reviews Chemistry · doi:10.1038/s41570-017-0031 · Cited by 664
Colour-barcoded magnetic microparticles for multiplexed bioassays
Lee, H., Kim, J., Kim, H., Kim, J., & Kwon, S. (2010) · Nature Materials · doi:10.1038/nmat2815 · Cited by 398
Zhou, L., Wang, R., Yao, C., Li, X., Wang, C., Zhang, X., Xu, C., Zeng, A., Zhao, D., & Zhang, F. (2015) · Nature Communications · doi:10.1038/ncomms7938 · Cited by 321
Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA
Lin, C., Jungmann, R., Leifer, A. M., Li, C., Levner, D., Church, G. M., Shih, W. M., & Yin, P. (2012) · Nature Chemistry · doi:10.1038/nchem.1451 · Cited by 302
Metadata
- Authors
- Dejneka, M. J., Streltsov, A., Pal, S., Frutos, A. G., Powell, C. L., Yost, K., Yuen, P. K., Müller, U., & Lahiri, J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2003-01-06
- Volume
- 100
- Issue
- 2
- Pages
- 389-393
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2167220827
- Cited by
- 208
- References
- 0
- FWCI
- 9.84
- Type
- journal article
- Language
- en
- Open access
- green
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- Dejneka, M. J., Streltsov, A., Pal, S., Frutos, A. G., Powell, C. L., Yost, K., Yuen, P. K., Müller, U., & Lahiri, J. (2003). Rare earth-doped glass microbarcodes. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0236044100
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