The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Abscisic acid-dependent multisite phosphorylation regulates the activity of a transcription activator AREB1
Open accessAbstract
bZIP-type transcription factors AREBs/ABFs bind an abscisic acid (ABA)-responsive cis-acting element named ABRE and transactivate downstream gene expression in Arabidopsis . Because AREB1 overexpression could not induce downstream gene expression, activation of AREB1 requires ABA-dependent posttranscriptional modification. We confirmed that ABA activated 42-kDa kinase activity, which, in turn, phosphorylated Ser/Thr residues of R-X-X-S/T sites in the conserved regions of AREB1. Amino acid substitutions of R-X-X-S/T sites to Ala suppressed transactivation activity, and multiple substitution of these sites resulted in almost complete suppression of transactivation activity in transient assays. In contrast, substitution of the Ser/Thr residues to Asp resulted in high transactivation activity without exogenous ABA application. A phosphorylated, transcriptionally active form was achieved by substitution of Ser/Thr in all conserved R-X-X-S/T sites to Asp. Transgenic plants overexpressing the phosphorylated active form of AREB1 expressed many ABA-inducible genes, such as RD29B , without ABA treatment. These results indicate that the ABA-dependent multisite phosphorylation of AREB1 regulates its own activation in plants.
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MYB transcription factors in Arabidopsis
Dubos, C., Stracke, R., Grotewold, E., Weisshaar, B., Martin, C., & Lepiniec, L. (2010) · Trends in Plant Science · doi:10.1016/j.tplants.2010.06.005 · Cited by 4,865
Abe, H., Urao, T., Ito, T., Seki, M., Shinozaki, K., & Yamaguchi-Shinozaki, K. (2003) · The Plant Cell · doi:10.1105/tpc.006130 · Cited by 2,285
Self-citationYamaguchi-Shinozaki, K., & Shinozaki, K. (1994) · The Plant Cell · doi:10.1105/tpc.6.2.251 · Cited by 1,993
Self-citationbZIP transcription factors in Arabidopsis
Jakoby, M., Weisshaar, B., Dröge-Laser, W., Vicente-Carbajosa, J., Tiedemann, J., Kroj, T., & Parcy, F. (2002) · Trends in Plant Science · doi:10.1016/s1360-1385(01)02223-3 · Cited by 1,849
Uno, Y., Furihata, T., Abe, H., Yoshida, R., Shinozaki, K., & Yamaguchi-Shinozaki, K. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.190309197 · Cited by 1,365
Self-citationMustilli, A.-C., Merlot, S., Vavasseur, A., Fenzi, F., & Giraudat, J. (2002) · The Plant Cell · doi:10.1105/tpc.007906 · Cited by 1,231
ABFs, a Family of ABA-responsive Element Binding Factors
Choi, H.-I., Hong, J.-H., Ha, J.-O., Kang, J.-Y., & Kim, S. Y. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.3.1723 · Cited by 1,218
ABSCISIC ACID SIGNAL TRANSDUCTION
Leung, J., & Giraudat, J. (1998) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.49.1.199 · Cited by 1,200
The Arabidopsis Abscisic Acid Response Gene ABI5 Encodes a Basic Leucine Zipper Transcription Factor
Finkelstein, R. R., & Lynch, T. J. (2000) · The Plant Cell · doi:10.1105/tpc.12.4.599 · Cited by 1,143
Fujita, Y., Fujita, M., Satoh, R., Maruyama, K., Parvez, M. M., Seki, M., Hiratsu, K., Ohme-Takagi, M., Shinozaki, K., & Yamaguchi-Shinozaki, K. (2005) · The Plant Cell · doi:10.1105/tpc.105.035659 · Cited by 998
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Abscisic Acid: Emergence of a Core Signaling Network
Cutler, S. R., Rodriguez, P. L., Finkelstein, R. R., & Abrams, S. R. (2010) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042809-112122 · Cited by 3,151
Gene networks involved in drought stress response and tolerance
Shinozaki, K., & Yamaguchi-Shinozaki, K. (2006) · Journal of Experimental Botany · doi:10.1093/jxb/erl164 · Cited by 2,632
Self-citationMolecular Aspects of Seed Dormancy
Finkelstein, R., Reeves, W., Ariizumi, T., & Steber, C. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092740 · Cited by 1,379
Transcriptional Regulatory Networks in Response to Abiotic Stresses in Arabidopsis and Grasses
Nakashima, K., Ito, Y., & Yamaguchi-Shinozaki, K. (2009) · Plant Physiology · doi:10.1104/pp.108.129791 · Cited by 1,250
Self-citationResearch on plant abiotic stress responses in the post‐genome era: past, present and future
Hirayama, T., & Shinozaki, K. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04124.x · Cited by 1,215
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Metadata
- Authors
- Furihata, T., Maruyama, K., Fujita, Y., Umezawa, T., Yoshida, R., Shinozaki, K., & Yamaguchi-Shinozaki, K.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2006-01-30
- Volume
- 103
- Issue
- 6
- Pages
- 1988-1993
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2060396596
- Cited by
- 847
- References
- 36
- FWCI
- 32.14
- Type
- journal article
- Language
- en
- Open access
- green
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