The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Biosynthesis of 2-methylbacteriohopanepolyols by an anoxygenic phototroph
Open accessAbstract
Sedimentary 2-methyhopanes have been used as biomarker proxies for cyanobacteria, the only known bacterial clade capable of oxygenic photosynthesis and the only group of organisms found thus far to produce abundant 2-methylbacteriohopanepolyols (2-MeBHPs). Here, we report the identification of significant quantities of 2-MeBHP in two strains of the anoxygenic phototroph Rhodopseudomonas palustris. Biosynthesis of 2-MeBHP can occur in the absence of O(2), deriving the C-2 methyl group from methionine. The relative abundance of 2-MeBHP varies considerably with culture conditions, ranging from 13.3% of total bacteriohopanepolyol (BHP) to trace levels of methylation. Analysis of intact BHPs reveals the presence of methylated bacteriohopane-32,33,34,35-tetrol but no detectable methylation of 35-aminobacteriohopane-32,33,34-triol. Our results demonstrate that an anoxygenic photoautotroph is capable of generating 2-MeBHPs and show that the potential origins of sedimentary 2-methylhopanoids are more diverse than previously thought.
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“For example, although 2-methyl hopanes are known to be the breakdown product of 2-methylbacteriohopanepolyols, which were once thought to be produced only by cyanobacteria, it has recently been shown that 2-methylbacteriohopanepolyols are produced by other bacteria as well (Rashby et al., 2007; Welander et al., 2012).”
From The Astrobiology Primer v2.0 (2016) · cites this paper as Rashby et al., 2007
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Self-citation2-Methylhopanoids as biomarkers for cyanobacterial oxygenic photosynthesis
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Self-citationPhotic Zone Euxinia During the Permian-Triassic Superanoxic Event
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Self-citationFractionation of Carbon and Hydrogen Isotopes in Biosynthetic Processes
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Metadata
- Authors
- Rashby, S. E., Sessions, A. L., Summons, R. E., & Newman, D. K.
- Affiliations
- California Institute of Technology (US)
- Massachusetts Institute of Technology (US)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2007-09-18
- Volume
- 104
- Issue
- 38
- Pages
- 15099-15104
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC1986619
- OpenAlex
- W2123257520
- Cited by
- 281
- References
- 51
- Citations by year
- 2026: 10 · 2025: 6 · 2024: 6 · 2023: 8 · 2022: 14 · 2021: 14 · 2020: 10 · 2019: 9 · 2018: 14 · 2017: 16 · 2016: 13 · 2015: 16 · 2014: 21 · 2013: 19 · 2012: 23
- FWCI
- 15.41
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- Funders
- National Science Foundation
- National Aeronautics and Space Administration
- Ames Research Center
- University of California, Davis
- Topics
- Physical Sciences › Earth and Planetary Sciences › Paleontology › Paleontology and Stratigraphy of Fossils
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Photosynthetic Processes and Mechanisms
- Physical Sciences › Environmental Science › Pollution › Microbial bioremediation and biosurfactants
- Keywords
- biosynthesis, Rhodopseudomonas palustris, anoxygenic phototrophs, bacteriohopanepolyols, sedimentary biomarkers, cyanobacteria, methylation
- MeSH terms
- Aerobiosis, Chromatography, Liquid, Gas Chromatography-Mass Spectrometry, Methylation, Photosynthesis, Rhodopseudomonas, Triterpenes, Phototrophic Processes
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