The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis
Open accessAbstract
Plaque angiogenesis promotes the growth of atheromas, but the functions of plaque capillaries are not fully determined. Neovascularization may act as a conduit for the entry of leukocytes into sites of chronic inflammation. We observe vasa vasorum density correlates highly with the extent of inflammatory cells, not the size of atheromas in apolipoprotein E-deficient mice. We show atherosclerotic aortas contain activities that promote angiogenesis. The angiogenesis inhibitor angiostatin reduces plaque angiogenesis and inhibits atherosclerosis. Macrophages in the plaque and around vasa vasorum are reduced, but we detect no direct effect of angiostatin on monocytes. After angiogenesis blockade in vivo , the angiogenic potential of atherosclerotic tissue is suppressed. Activated macrophages stimulate angiogenesis that can further recruit inflammatory cells and more angiogenesis. Our findings demonstrate that late-stage inhibition of angiogenesis can interrupt this positive feedback cycle. Inhibition of plaque angiogenesis and the secondary reduction of macrophages may have beneficial effects on plaque stability.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Small-molecule drugs like the fumagillin analogue TNP-470, endostatin or angiostatin reduced plaque angiogenesis and inhibited advanced atherosclerosis in APOE-knockout mice after prolonged treatment for 16 weeks105,106.”
From Perspectives and opportunities for nanomedicine in the management of atherosclerosis (2011) · cites this paper as [106]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Atherosclerosis--an inflammatory disease
Ross, R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901143400207 · Cited by 21,725
Angiogenesis in cancer, vascular, rheumatoid and other disease
Folkman, J. (1995) · Nature Medicine · doi:10.1038/nm0195-27 · Cited by 7,627
Self-citationRidker, P. M., Hennekens, C. H., Buring, J. E., & Rifai, N. (2000) · New England Journal of Medicine · doi:10.1056/nejm200003233421202 · Cited by 5,850
OʼReilly, M. (1994) · Cell · doi:10.1016/0092-8674(94)90200-3 · Cited by 3,344
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
Bergers, G., Brekken, R., McMahon, G., Vu, T. H., Itoh, T., Tamaki, K., Tanzawa, K., Thorpe, P., Itohara, S., Werb, Z., et al. (2000) · Nature Cell Biology · doi:10.1038/35036374 · Cited by 2,797
Söker, S., Takashima, S., Miao, H. Q., Neufeld, G., & Klagsbrun, M. (1998) · Cell · doi:10.1016/s0092-8674(00)81402-6 · Cited by 2,493
Gu, L., Okada, Y., Clinton, S. K., Gerard, C. J., Sukhova, G. K., Libby, P., & Rollins, B. J. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80139-2 · Cited by 1,574
Barleon, B., Sozzani, S., Zhou, D., Weich, H., Mantovani, A., & Marmé, D. (1996) · Blood · doi:10.1182/blood.v87.8.3336.bloodjournal8783336 · Cited by 1,350
A major role for VCAM-1, but not ICAM-1, in early atherosclerosis
Cybulsky, M. I., Iiyama, K., Li, H., Zhu, S.-N., Chen, M., Iiyama, M., Davis, V., Gutierrez-Ramos, J.-C., Connelly, P. W., & Milstone, D. S. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11871 · Cited by 1,244
Davies, M. J., Richardson, P. D., Woolf, N., Katz, D. R., & Mann, J. (1993) · Heart · doi:10.1136/hrt.69.5.377 · Cited by 1,127
Research works printed but not linked: 5
- J C Paterson Arch Pathol 25, 474–487 (1938).
- E R O'Brien, M R Garvin, R Dev, D K Stewart, T Hinohara, J B Simpson, S M Schwartz Am J Pathol 145, 883–894 (1994).
- R F Nicosia, A Ottinetti Lab Invest 63, 115–122 (1990).
- J Fang, L Yan, Y Shing, M A Moses Cancer Res 61, 5731–5735 (2001).
- R F Nicosia, Y J Lin, D Hazelton, X Qian Am J Pathol 151, 1379–1386 (1997).
Cited by
Sorted by citations
Items 401–500 of 649
Dubner, A., Lu, S., Jolly, A., Strand, K. A., Mutryn, M. F., Hinthorn, T., Noble, T. D., Nemenoff, R. A., Moulton, K. S., Majesky, M. W., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.174639 · Cited by 17
Self-citationEpsins in vascular development, function and disease
Bhattacharjee, S., Lee, Y., Zhu, B., Wu, H., Chen, Y., & Chen, H. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03642-4 · Cited by 18
Degnan, A. J., Young, V. E. L., & Gillard, J. H. (2011) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.11.168 · Cited by 17
Kalayinia, S., Ziaee, S., Boroumand, M. A., Anvari, M. S., Pourgholi, L., & Jalali, A. (2016) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.22066 · Cited by 16
Advances in imaging angiogenesis and inflammation in atherosclerosis
Zagorchev, L., & Mulligan‐Kehoe, M. J. (2011) · Thrombosis and Haemostasis · doi:10.1160/th10-08-0562 · Cited by 16
Efficacy of high-resolution cone-beam CT in the evaluation of carotid atheromatous plaque
Tanabe, J., Tanaka, M., Kadooka, K., & Hadeishi, H. (2015) · Journal of NeuroInterventional Surgery · doi:10.1136/neurintsurg-2014-011584 · Cited by 16
Kampschulte, M., Gunkel, I. A., Stieger, P., Sedding, D., Brinkmann, A., Ritman, E. L., Krombach, G. A., & Langheinrich, A. C. (2014) · International journal of cardiac imaging · doi:10.1007/s10554-014-0380-5 · Cited by 16
Klegerman, M. E., Naji, A. K., Haworth, K. J., Zou, Y., Golunski, E., Peng, T., Britton, G. L., Huang, S. L., Holland, C. K., & McPherson, D. D. (2015) · Journal of Liposome Research · doi:10.3109/08982104.2015.1029494 · Cited by 16
SLEVIN, M. A., Turu, M. M., Rovira, N., Luque, A., Baldellou, M., Krupiński, J., & Badimón, L. (2009) · Journal of Vascular Research · doi:10.1159/000265566 · Cited by 16
The role of cytokines in cardiovascular disease in menopause
Camilleri, G., Borg, M., Brincat, S. D., Schembri-Wismayer, P., Brincat, M., & Calleja‐Agius, J. (2012) · Climacteric · doi:10.3109/13697137.2012.700743 · Cited by 16
TNP-470, an Angiogenesis Inhibitor, Attenuates the Development of Allograft Vasculopathy
Denton, M., Magee, C., Melter, M., Dharnidharka, V. R., Sayegh, M. H., & Briscoe, D. M. (2004) · Transplantation · doi:10.1097/01.tp.0000137266.30134.02 · Cited by 16
Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs
Albini, A., Indraccolo, S., Noonan, D. M., & Pfeffer, U. (2010) · Clinical & Experimental Metastasis · doi:10.1007/s10585-010-9312-5 · Cited by 16
Bruneau, S., Datta, D. B., Flaxenburg, J. A., Pal, S., & Briscoe, D. M. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.01.128 · Cited by 16
Immune cells and vasa vasorum in the tunica media of atherosclerotic coronary arteries
Zorc‐Pleskovič, R., Pleskovič, A., Vraspir-Porenta, O., Zorc, M., & Milutinović, A. (2018) · Bosnian Journal of Basic Medical Sciences · doi:10.17305/bjbms.2018.2951 · Cited by 16
Atherosclerosis and Cancer: Flip Sides of the Neoplastic Response in Mammalian Cells?
Ramos, K. S., & Partridge, C. R. (2005) · Cardiovascular Toxicology · doi:10.1385/ct:5:3:245 · Cited by 16
Control of atherosclerotic plaque vulnerability: Insights from transgenic mice
Heeneman, S. (2008) · Frontiers in bioscience · doi:10.2741/3155 · Cited by 16
Induction of Myeloid-Derived Suppressor Cells in Cryopyrin-Associated Periodic Syndromes
Ballbach, M., Hall, T., Brand, A., Neri, D., Singh, A., Schäfer, I., Herrmann, E. M., Hansmann, S., Handgretinger, R., Kuemmerle-Deschner, J. B., et al. (2016) · Journal of Innate Immunity · doi:10.1159/000446615 · Cited by 15
Ogeng’o, J. A., Ongeti, K. W., Obimbo, M., Olabu, B. O., & Mwachaka, P. (2014) · Anatomy Research International · doi:10.1155/2014/456741 · Cited by 15
Galis, Z. S., & Lessner, S. M. (2009) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2009.06.001 · Cited by 15
Goertz, D. E., Frijlink, M. E., Krams, R., de Jong, N., & van der Steen, A. F. W. (2007) · Netherlands Heart Journal · doi:10.1007/bf03085959 · Cited by 15
Involvement of circulating endothelial progenitor cells in carotid plaque growth and vulnerability
Kashiwazaki, D., Akioka, N., Kuwayama, N., Hayashi, T., Noguchi, K., Tanaka, K., & Kuroda, S. (2016) · Journal of neurosurgery · doi:10.3171/2015.10.jns151500 · Cited by 15
Angiogenesis: A link to Thrombosis in Athero-thrombotic Disease
Conway, E. M. (2003) · Pathophysiology of Haemostasis and Thrombosis · doi:10.1159/000083809 · Cited by 15
Extracellular Adenosine Triphosphate
Gerasimovskaya, E. V., Davie, N. J., Ahmad, S., Tucker, D. A., White, C. W., & Stenmark, K. R. (2005) · CHEST Journal · doi:10.1378/chest.128.6_suppl.608s · Cited by 15
Stefanadis, C., Toutouzas, K. P., Tsiamis, E. G., Vavuranakis, M., Stefanadi, E., & Kipshidze, N. N. (2008) · EuroIntervention · doi:10.4244/eijv3i4a82 · Cited by 15
Causal role of circulating inflammatory cytokines in cardiac diseases, structure and function
Ruan, W., Zhou, X., Liu, H., Wang, T., Zhang, G., & Lin, K. (2024) · Heart & Lung · doi:10.1016/j.hrtlng.2024.04.018 · Cited by 13
Ahn, J., Sei, Y. J., Jeon, N. L., & Kim, Y. (2018) · IEEE Transactions on Nanotechnology · doi:10.1109/tnano.2017.2771426 · Cited by 14
Vascularization of the arteriovenous fistula wall and association with maturation outcomes
Duque, J. C., Martinez, L., Tabbara, M., Parikh, P. P., Paez, A., Selman, G., Salman, L. H., Velazquez, O. C., & Vázquez-Padrón, R. I. (2019) · The Journal of Vascular Access · doi:10.1177/1129729819863584 · Cited by 14
Non-invasive vulnerable plaque imaging: how do we know that treatment works?
Sannino, A., Brevetti, L., Giugliano, G., Scudiero, F., Toscano, E., Mainolfi, C. G., Cuocolo, A., Perrino, C., Stabile, E., Trimarco, B., et al. (2014) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeu097 · Cited by 14
Role of Vasa Vasorum in Arterial Disease: A Re-emerging Factor
Ritman, E. L., & Lerman, A. (2007) · Current Cardiology Reviews · doi:10.2174/157340307779939907 · Cited by 14
Liu, C., Wang, S., Metharom, P., & Caplice, N. M. (2009) · Journal of Vascular Research · doi:10.1159/000226226 · Cited by 14
Sata, M., & Nagai, R. (2004) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2004.01.011 · Cited by 14
The Role of Fibroblasts in Atherosclerosis Progression
Kuret, T., & Sodin‐Šemrl, S. (2021) · Biochemistry · doi:10.5772/intechopen.98546 · Cited by 13
Huang, D. Y., Liu, G., Xu, Z., Chen, S., Wang, C., Liu, D., Cao, J., Cheng, J., Wu, B., & Wu, D. (2022) · Genes & Diseases · doi:10.1016/j.gendis.2022.10.017 · Cited by 13
Progression in Atherosclerosis
Plasschaert, H., Heeneman, S., & Daemen, M. J. A. P. (2009) · Topics in Magnetic Resonance Imaging · doi:10.1097/rmr.0b013e3181ea2869 · Cited by 13
Rosàs, E., Santomá, P., Duran‐Frigola, M., Hernandez, B., Llinàs, M. C., Ruiz‐González, R., Nonell, S., Sánchez‐García, D., Edelman, E. R., & Balcells, M. (2013) · Langmuir · doi:10.1021/la401067d · Cited by 13
Senescence and its bypass in the vascular endothelium
Deborah, A. F. (2005) · Frontiers in bioscience · doi:10.2741/1588 · Cited by 13
Effects of Oxidized Phospholipids on Gene Expression in RAW 264.7 Macrophages: A Microarray Study
Koller, D., Hackl, H., Bogner‐Strauß, J. G., & Hermetter, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0110486 · Cited by 13
Kawasaki, Y., Yokobayashi, E., Sakamoto, K., Tenma, E., Haruka, T., Chiba, Y., Otashiro, T., Ishihara, M., Yonezawa, S., Sugiyama, A., et al. (2015) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2015.10.001 · Cited by 13
Kaul, S., & Lindner, J. R. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.11.010 · Cited by 13
Intrusion Through the Fragile Back Door
Mause, S. F., & Weber, C. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.01.047 · Cited by 13
Li, Z., Wang, Q., Jing, H., Luo, X., Du, L., & Duan, Y. (2021) · ACS Applied Nano Materials · doi:10.1021/acsanm.1c02009 · Cited by 12
Endostatin in disease modulation: From cancer to beyond
Anakha, J., Prasad, Y. R., & Pande, A. H. (2024) · Vascular Pharmacology · doi:10.1016/j.vph.2024.107459 · Cited by 12
Gössl, M., Lerman, L. O., & Lerman, A. (2007) · Journal of the American Society of Nephrology · doi:10.1681/asn.2007030333 · Cited by 12
Resveratrol-Coated Balloon Catheters in Porcine Coronary and Peripheral Arteries
Kamann, S., Haase, T., Stolzenburg, N., Löchel, M., Peters, D., & Schnorr, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20092285 · Cited by 12
Novel risk factors for acute coronary syndromes and emerging therapies
Tong, D. C., Wilson, A., & Layland, J. J. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.06.148 · Cited by 12
Joo, S.-P., Lee, S.-W., Cho, Y.-H., Kim, Y.-S., Seo, B.-R., Kim, H.-S., & Kim, T. (2019) · Journal of Korean Neurosurgical Society · doi:10.3340/jkns.2019.0077 · Cited by 12
Ex Vivo Mouse Aortic Ring Angiogenesis Assay
Mehta, V., & Mahmoud, M. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2217-9_17 · Cited by 12
Yang, P., Rui, Y., Lu, L., Li, T., Liu, S.-Q., Yan, H., & Wang, H. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.01.038 · Cited by 12
Vavuranakis, M., Papaioannou, T. G., Kakadiaris, I. A., O’Malley, S. M., Naghavi, M., Filis, K., Sanidas, E. A., Papalois, A. E., Stamatopoulos, I., & Stefanadis, C. (2007) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2007.04721.x · Cited by 12
Effects of plant extracts on angiogenic activities of endothelial cells and keratinocytes.
Łoboda, A., Cisowski, J., Zarebski, A. P., Jaźwa, A., Núńez, D. R., Kypriotakis, Z., Heinrich, M., & Dulak, J. (2005) · PubMed · Cited by 12
Zinc Finger Protein 202: A new candidate gene for ischemic heart disease
Stene, M. C. A., Frikke‐Schmidt, R., Nordestgaard, B. G., Steffensen, R., Schnohr, P., & Tybjærg‐Hansen, A. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.10.014 · Cited by 12
Regulation of Vulnerable Plaque Development by the Heme Oxygenase/Carbon Monoxide System
Larsen, K., Cheng, C., & Duckers, H. J. (2010) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2010.04.001 · Cited by 12
NOX4 mRNA correlates with plaque stability in patients with carotid artery stenosis
Hofmann, A., Frank, F., Wolk, S., Busch, A., Klimová, A., Sabarstinski, P., Gerlach, M., Egorov, D., Kopaliani, I., Weinert, S., et al. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102473 · Cited by 11
Wang, L., Luo, W., Zhang, S., Zhang, J., He, L., Shi, Y., Gao, L., Wu, B., Nie, X., Hu, C., et al. (2024) · Cardiovascular Research · doi:10.1093/cvr/cvae131 · Cited by 11
Burke‐Kleinman, J., & Gotlieb, A. I. (2023) · American Journal Of Pathology · doi:10.1016/j.ajpath.2023.06.003 · Cited by 11
Téllez, A., Schuster, D. S., Alviar, C. L., López-Berenstein, G., Sanguino, A. M., Ballantyne, C. M., Perrard, X. D., Schulz, D. G., Rousselle, S. D., Kałuża, G. L., et al. (2011) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2011.03.007 · Cited by 11
Patel, O., Wilson, W. B., & Qin, Z. (2013) · BioMetals · doi:10.1007/s10534-013-9624-4 · Cited by 11
ENDOTHELIAL MECHANOTRANSDUCTION MECHANISMS FOR VASCULAR PHYSIOLOGY AND ATHEROSCLEROSIS
Zhou, T. G., Zheng, Y., Qiu, J., Hu, J., Sun, D., Tang, C., & Wang, G. (2014) · Journal of Mechanics in Medicine and Biology · doi:10.1142/s0219519414300063 · Cited by 12
Ma, L., Liu, X., Lu, H., Yang, X., Wang, Y., Zhang, C., Ni, M., Zhao, Y., & Zhang, Y. (2015) · European Heart Journal Supplements · doi:10.1093/eurheartj/suv020 · Cited by 11
Delivery of bevacizumab to atheromatous porcine carotid tissue using echogenic liposomes
Sutton, J. T., Haworth, K. J., Shanmukhappa, S. K., Moody, M. R., Klegerman, M. E., Griffin, J. K., Patton, D. M., McPherson, D. D., & Holland, C. K. (2016) · Drug Delivery · doi:10.1080/10717544.2016.1212441 · Cited by 11
Kohnken, R. A., Scansen, B. A., & Premanandan, C. (2016) · Veterinary Pathology · doi:10.1177/0300985816685137 · Cited by 11
Coronary Artery Plaque Imaging
Xie, Y., Jin, H. M., Zeng, M., & Li, D. (2017) · Current Atherosclerosis Reports · doi:10.1007/s11883-017-0672-z · Cited by 11
Synthetic approaches towards cortistatins: evolution and progress through its ages
Indu, S., & Kaliappan, K. P. (2020) · Organic & Biomolecular Chemistry · doi:10.1039/d0ob00770f · Cited by 11
Nishida, T., Hiro, T., Takayama, T., Sudo, M., Haruta, H., Fukamachi, D., Hirayama, A., & Okumura, Y. (2021) · Heart and Vessels · doi:10.1007/s00380-020-01756-0 · Cited by 11
Injury to the tunica media initiates atherogenesis in the presence of hyperlipidemia
Belhoul‐Fakir, H., Wu, J., Yeow, Y. L., Musk, G. C., Kershaw, H., Ingley, E., Zhao, B. S., Reid, C. M., Lagat, C., Evans, B. J., et al. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1152124 · Cited by 11
Salami, A., & Shamieh, S. E. (2019) · Medicina · doi:10.3390/medicina55080464 · Cited by 11
Conen, K. L., Jeanneret, C., Hecker, B., Cathomas, G., & Biedermann, B. C. (2006) · Arthritis & Rheumatism · doi:10.1002/art.21656 · Cited by 11
Okeda, T. (1992) · Biomedicine & Pharmacotherapy · doi:10.1016/0753-3322(92)90296-j · Cited by 11
Inhibition of Endothelial Inflammatory Response by HT-C6, a Hydroxytyrosol Alkyl Ether Derivative
Marrero, A. D., Castilla, L., Bernal, M., Manrique-Poyato, M. I., Posligua-García, J. D., Moya‐Utrera, F., Porras-Alcalá, C., Espartero, J. L., Sarabia, F., Quesada, A. R., et al. (2023) · Antioxidants · doi:10.3390/antiox12081513 · Cited by 10
Antisense Oligonucleotides, microRNAs, and Antibodies
Dávalos, A., & Chroni, A. (2014) · Handbook of experimental pharmacology · doi:10.1007/978-3-319-09665-0_22 · Cited by 10
Nogo‐B expression, in arterial intima, is impeded in the early stages of atherosclerosis in humans
Drożdż, K., Grzegorek, I., Chmielewska, M., Gomułkiewicz, A., Jabłońska, K., Piotrowska, A., Karczewski, M., Janczak, D., Patrzałek, D., Dzięgiel, P., et al. (2013) · Apmis · doi:10.1111/apm.12212 · Cited by 10
C‐reactive protein and coronary composition in patients with percutaneous revascularization
Pucci, A., Brscic, E., Tessitore, E., Celeste, A., Crudelini, M., Bernardi, A. D., Alberti, A., Biondi‐Zoccai, G., & Sheiban, I. (2008) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2008.01944.x · Cited by 10
Vascular Toxicities of Cancer Therapies
Herrmann, J., & Lerman, A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-44227-5.00009-0 · Cited by 9
Rey, N., Ebrahimian, T. G., Gloaguen, C., Kereselidze, D., Magneron, V., Bontemps, C. A., Demarquay, C., Olsson, G., Haghdoost, S., Lehoux, S., et al. (2021) · Dose-Response · doi:10.1177/15593258211016237 · Cited by 9
Vavuranakis, M., Kakadiaris, I. A., Papaioannou, T., O’Malley, S. M., CARLIER, S. G., Naghavi, M., & Stefanadis, C. (2007) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.5.5.917 · Cited by 9
Imaging of intraplaque haemorrhage
Prati, F., & Vito, L. D. (2012) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0b013e328357a665 · Cited by 9
Statin treatment decreases serum angiostatin levels in patients with ischemic heart disease
Tykhomyrov, A. A., Nedzvetsky, V. S., Bardachenko, N., Гриненко, Т. В., & Kuryata, O. V. (2015) · Life Sciences · doi:10.1016/j.lfs.2015.05.008 · Cited by 9
Identification of interleukin-2 for imaging atherosclerotic inflammation
Fayad, Z. A., Amirbekian, V., Toussaint, J., & Fuster, V. (2005) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-005-1981-y · Cited by 9
Miyachi, H., Tara, S., Nakayama, H., Hama, R., Sugiura, T., Reinhardt, J. W., Yi, T., Lee, Y., Lee, A. Y., Miyamoto, S., et al. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.05.055 · Cited by 8
Zabihi, A. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.143838 · Cited by 8
Atherogenesis, Transcytosis, and the Transmural Cholesterol Flux: A Critical Review
Goldberg, D., & Khatib, S. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/2253478 · Cited by 10
Parametric Subharmonic Imaging Using a Commercial Intravascular Ultrasound Scanner
Eisenbrey, J. R., Sridharan, A. N., deMuinck, E. D., Doyley, M. M., & Forsberg, F. (2012) · Journal of Ultrasound in Medicine · doi:10.7863/jum.2012.31.3.361 · Cited by 8
Sun, M., Ji, J., Guo, X., Liu, W., Wang, Y., Ma, S., Hu, W., Wang, J., & Jiang, F. (2015) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2015.12.001 · Cited by 8
Construction of key building blocks towards the synthesis of cortistatins
Indu, S., Telore, R. D., & Kaliappan, K. P. (2020) · Organic & Biomolecular Chemistry · doi:10.1039/d0ob00170h · Cited by 8
Vidal, I., Castilla, L., Marrero, A. D., Bravo-Ruiz, I., Bernal, M., Manrique-Poyato, M. I., Quesada, A. R., Medina, M. Á., & Martı́nez-Poveda, B. (2022) · Marine Drugs · doi:10.3390/md20100605 · Cited by 8
Animal models for large vessel vasculitis – The unmet need
Chu, C. (2023) · Rheumatology and Immunology Research · doi:10.2478/rir-2023-0002 · Cited by 8
Sepp, D., Esposito, L., Zepper, P., Ott, I., Feurer, R., Sadikovic, S., Hemmer, B., & Poppert, H. (2009) · Vascular Cell · doi:10.1186/2040-2384-1-10 · Cited by 8
Recent updates on echocardiography and ultrasound for Kawasaki disease: beyond the coronary artery
Noto, N., Komori, A., Ayusawa, M., & Takahashi, S. (2018) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt.2017.06.09 · Cited by 8
Xu, W., Yu, C., Piao, L., Inoue, A., Wang, H., Meng, X., Li, X., Cui, L., Umegaki, H., Shi, G., et al. (2019) · Circulation Journal · doi:10.1253/circj.cj-19-0325 · Cited by 9
Baklanov, D. V., Peters, K. G., Seidel, A. L., Taylor, D. A., & Annex, B. H. (2003) · Vascular Medicine · doi:10.1191/1358863x03vm488oa · Cited by 8
Wu, Y., Chen, J., Tsai, H., Leu, H., Chang, C., & Chang, T. (2025) · British Journal of Pharmacology · doi:10.1111/bph.17451 · Cited by 8
Molecular imaging of cardiovascular disease: Current status and future perspective
Nakahara, T., Fujimoto, S., & Jinzaki, M. (2025) · Journal of Cardiology · doi:10.1016/j.jjcc.2025.01.017 · Cited by 7
Li, Y., Zhang, L., Yang, W., Lin, L., Pan, J., Lu, M., Zhang, Z., Li, Y., & Li, C. (2024) · Phytotherapy Research · doi:10.1002/ptr.8257 · Cited by 8
Zhao, B. S., Belhoul‐Fakir, H., Jansen, S. J., Hamzah, J., Mishani, S., & Lawrence‐Brown, M. M. D. (2020) · Journal of Anatomy · doi:10.1111/joa.13324 · Cited by 7
Díaz‐Flores, L., Gutiérrez, R., García, M. P., Gayoso, S., Carrasco, J. L., Díaz-Flores, L., González‐Gómez, M., & Madrid, J. F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218049 · Cited by 7
Aortic injury is common following pulmonary vein isolation
Tung, P., Hong, S. N., Chan, R. H. M., Peters, D. C., Hauser, T. H., Manning, W. J., & Josephson, M. E. (2013) · Heart Rhythm · doi:10.1016/j.hrthm.2013.01.012 · Cited by 7
Effects of tongxinluo on angiogenesis in the carotid adventitia of hyperlipidemic rabbits
Zhou, J., Cao, B., Ju, W., Liu, S., Song, J., & Liu, L. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5675 · Cited by 7
Bosevski, M., Borozanov, V., Tosev, S., & Lj, G.-I. (2007) · International Journal of Cardiology · doi:10.1016/j.ijcard.2007.08.011 · Cited by 7
Rheumatoid disease and ischaemic heart disease: Insights from pathophysiology and vascular biology
Bhatia, G. S., Sosin, M. D., Khattak, F., Davis, R., & Lip, G. Y. H. (2005) · International Journal of Cardiology · doi:10.1016/j.ijcard.2004.12.064 · Cited by 7
Murine Models of Advanced Atherosclerosis
Rosenfeld, M. E., & Schwartz, S. M. (2006) · Wiley eBooks · doi:10.1002/9780470987575.ch7 · Cited by 6
Metadata
- Authors
- Moulton, K. S., Vakili, K., Zurakowski, D., Soliman, M., Butterfield, C., Sylvin, E., Lo, K.-M., Gillies, S., Javaherian, K., & Folkman, J.
- Affiliations
- Boston University (US)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2003-04-07
- Volume
- 100
- Issue
- 8
- Pages
- 4736-4741
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC153625
- OpenAlex
- W2146672236
- Semantic Scholar
- 82c000d66a80c8c81b76c493b4ef41413cde3f9b
- Cited by
- 652
- References
- 32
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 12 · 2023: 15 · 2022: 15 · 2021: 16 · 2020: 18 · 2019: 19 · 2018: 13 · 2017: 19 · 2016: 35 · 2015: 29 · 2014: 35 · 2013: 30 · 2012: 27
- FWCI
- 14.61
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Heart, Lung, and Blood Institute
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cerebrovascular and Carotid Artery Diseases
- Keywords
- atherosclerosis, plaque neovascularization, angiogenesis inhibition, angiostatin, macrophage accumulation, vasa vasorum, ApoE-deficient mice, plaque stability, chronic inflammation, leukocyte recruitment, positive feedback loop
- MeSH terms
- Animals, Apolipoproteins E, Arteriosclerosis, Feedback, Inflammation, Lymphokines, Macrophages, Mice, Inbred C57BL, Monocytes, Neovascularization, Pathologic, Peptide Fragments, Plasminogen, Receptors, LDL, Vasa Vasorum, Endothelial Growth Factors, Mice, Knockout, Chemokine CCL2, Intercellular Signaling Peptides and Proteins, Vascular Endothelial Growth Factors, Vascular Endothelial Growth Factor A, Angiostatins, Mice, In Vitro Techniques
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review