The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Genome-wide analysis of histone H3.1 and H3.3 variants in Arabidopsis thaliana
Open accessAbstract
Nucleosomes package eukaryotic DNA and are composed of four different histone proteins, designated H3, H4, H2A, and H2B. Histone H3 has two main variants, H3.1 and H3.3, which show different genomic localization patterns in animals. We profiled H3.1 and H3.3 variants in the genome of the plant Arabidopsis thaliana and found that the localization of these variants shows broad similarity in plants and animals, along with some unique features. H3.1 was enriched in silent areas of the genome, including regions containing the repressive chromatin modifications H3 lysine 27 methylation, H3 lysine 9 methylation, and DNA methylation. In contrast, H3.3 was enriched in actively transcribed genes, especially peaking at the 3′ end of genes, and correlated with histone modifications associated with gene activation, such as histone H3 lysine 4 methylation and H2B ubiquitylation, as well as RNA Pol II occupancy. Surprisingly, both H3.1 and H3.3 were enriched on defined origins of replication, as was overall nucleosome density, suggesting a novel characteristic of plant origins. Our results are broadly consistent with the hypothesis that H3.1 acts as the canonical histone that is incorporated during DNA replication, whereas H3.3 acts as the replacement histone that can be incorporated outside of S-phase during chromatin-disrupting processes like transcription.
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Cites
Mapping and quantifying mammalian transcriptomes by RNA-Seq
Mortazavi, A., Williams, B. A., McCue, K., Schaeffer, L., & Wold, B. (2008) · Nature Methods · doi:10.1038/nmeth.1226 · Cited by 13,696
Conservation and divergence of methylation patterning in plants and animals
Feng, S., Cokus, S. J., Zhang, X., Chen, P.-Y., Bostick, M., Goll, M. G., Hetzel, J., Jain, J., Strauss, S. H., Halpern, M. E., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002720107 · Cited by 1,285
Self-citationWhole-Genome Analysis of Histone H3 Lysine 27 Trimethylation in Arabidopsis
Zhang, X., Clarenz, O., Cokus, S., Bernatavichute, Y. V., Pellegrini, M., Goodrich, J., & Jacobsen, S. E. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050129 · Cited by 767
Self-citationHistone H2A.Z and DNA methylation are mutually antagonistic chromatin marks
Zilberman, D., Coleman-Derr, D., Ballinger, T., & Henikoff, S. (2008) · Nature · doi:10.1038/nature07324 · Cited by 593
Bernatavichute, Y. V., Zhang, X., Cokus, S., Pellegrini, M., & Jacobsen, S. E. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003156 · Cited by 333
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Cited by
The Physcomitrella patens chromosome‐scale assembly reveals moss genome structure and evolution
Lang, D., Ullrich, K. K., Murat, F., Fuchs, J., Jenkins, J., Haas, F. B., Piednoel, M., Gundlach, H., Van Bel, M., Meyberg, R., et al. (2018) · The Plant Journal · doi:10.1111/tpj.13801 · Cited by 423
Lee, S. C., Adams, D. W., Ipsaro, J. J., Cahn, J., Lynn, J., Kim, H.-S., Berube, B., Major, V., Calarco, J. P., LeBlanc, C., et al. (2023) · Cell · doi:10.1016/j.cell.2023.08.001 · Cited by 89
Metadata
- Authors
- Stroud, H., Otero, S., Desvoyes, B., Ramírez-Parra, E., Jacobsen, S. E., & Gutierrez, C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2012-03-19
- Volume
- 109
- Issue
- 14
- Pages
- 5370-5375
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2076444968
- Cited by
- 243
- References
- 5
- FWCI
- 7.43
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Stroud, H., Otero, S., Desvoyes, B., Ramírez-Parra, E., Jacobsen, S. E., & Gutierrez, C. (2012). Genome-wide analysis of histone H3.1 and H3.3 variants in Arabidopsis thaliana. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1203145109
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