Combining two strategies to improve perfusion and drug delivery in solid tumors

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

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Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy

Jain, R. K. (2005) · Science · doi:10.1126/science.1104819 · Cited by 5,527

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

Olive, K. P., Jacobetz, M. A., Davidson, C. J., Gopinathan, A., McIntyre, D., Honess, D., Madhu, B., Goldgraben, M. A., Caldwell, M. E., Allard, D., et al. (2009) · Science · doi:10.1126/science.1171362 · Cited by 3,170

Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

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Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy

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Phase III Trial of Nanoparticle Albumin-Bound Paclitaxel Compared With Polyethylated Castor Oil–Based Paclitaxel in Women With Breast Cancer

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EMT and Dissemination Precede Pancreatic Tumor Formation

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AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients

Batchelor, T. T., Sorensen, A. G., di Tomaso, E., Zhang, W.-T., Duda, D. G., Cohen, K. S., Kozak, K. R., Cahill, D. P., Chen, P.-J., Zhu, M., et al. (2007) · Cancer Cell · doi:10.1016/j.ccr.2006.11.021 · Cited by 1,769

Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer

O’Brien, M. E. R., Wigler, N., Inbar, M., Rosso, R., Grischke, E., Santoro, A., Catane, R., Kieback, D., Tomczak, P., Ackland, S. P., et al. (2004) · Annals of Oncology · doi:10.1093/annonc/mdh097 · Cited by 1,739

Nanogel-based nitric oxide-driven nanomotor for deep tissue penetration and enhanced tumor therapy

Wang, J., Liu, J., Sümbelli, Y., Shao, J., Shi, X., & van Hest, J. C. M. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.06.021 · Cited by 30

Strategies to enhance the penetration of nanomedicine in solid tumors

Liu, S., Ren, Z., Yan, M., Ye, W., & Hu, Y. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123315 · Cited by 34

In-silico dynamic analysis of cytotoxic drug administration to solid tumours: Effect of binding affinity and vessel permeability

Vavourakis, V., Stylianopoulos, T., & Wijeratne, P. A. (2018) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006460 · Cited by 30

Multistep, effective drug distribution within solid tumors

Shemi, A., Khvalevsky, E. Z., Gabai, R. M., Domb, A. J., & Barenholz, Y. (2015) · Oncotarget · doi:10.18632/oncotarget.5051 · Cited by 30

Nanomedicine and chemotherapeutics drug delivery: challenges and opportunities

Nezhadi, S., Saadat, E., Handali, S., & Dorkoosh, F. A. (2020) · Journal of drug targeting · doi:10.1080/1061186x.2020.1808000 · Cited by 28

Metronomic Anti-Cancer Therapy: A Multimodal Therapy Governed by the Tumor Microenvironment

Muñoz, R., Girotti, A., Hileeto, D., & Arias, F. J. (2021) · Cancers · doi:10.3390/cancers13215414 · Cited by 31

Physical Forces in Glioblastoma Migration: A Systematic Review

Grossen, A. A., Smith, K., Coulibaly, N. J. O., Arbuckle, B., Evans, A., Wilhelm, S., Jones, K. L., Dunn, I. F., Towner, R. A., Wu, D. H., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23074055 · Cited by 29

Extension of a multiphase tumour growth model to study nanoparticle delivery to solid tumours

Wirthl, B., Kremheller, J., Schrefler, B. A., & Wall, W. A. (2020) · PLoS ONE · doi:10.1371/journal.pone.0228443 · Cited by 29

The spatiotemporal journey of nanomedicines in solid tumors on their therapeutic efficacy

Qin, M., Xia, H., Xu, W., Chen, B., & Wang, Y. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.115137 · Cited by 31

Transport and Lymphatic Uptake of Biotherapeutics Through Subcutaneous Injection

Han, D., Rahimi, E., Aramideh, S., & Ardekani, A. M. (2021) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2021.09.045 · Cited by 28

Programmable intratumoral drug delivery to breast cancer using wireless bioelectronic device with electrochemical actuation

Souri, M., Elahi, S., & Soltani, M. (2024) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2024.2323211 · Cited by 28

The key role of matrix stiffness in colorectal cancer immunotherapy: mechanisms and therapeutic strategies

Chen, E., Zeng, Z., & Zhou, W. (2024) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2024.189198 · Cited by 30

Breaking barriers: enhancing CAR-armored T cell therapy for solid tumors through microenvironment remodeling

Andreou, T., Neophytou, C., Kalli, M., Mpekris, F., & Stylianopoulos, T. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1638186 · Cited by 27

Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients

Urup, T. H., Michaelsen, S. R., Olsen, L. R., Toft, A. D., Christensen, I. J., Grunnet, K., Winther, O., Broholm, H., Kosteljanetz, M., Issazadeh‐Navikas, S., et al. (2016) · Molecular Oncology · doi:10.1016/j.molonc.2016.05.005 · Cited by 28

Photoacoustic imaging for the evaluation of early tumor response to antivascular treatment

Yang, J., Guang, Z., Li, Q., Liao, C., Huang, L., Ke, T., Jiang, H., & Dan, H. (2019) · Quantitative Imaging in Medicine and Surgery · doi:10.21037/qims.2018.11.06 · Cited by 26

Tumor-Derived Extracellular Vesicles Induce Abnormal Angiogenesis via TRPV4 Downregulation and Subsequent Activation of YAP and VEGFR2

Guarino, B. D., Katari, V., Adapala, R. K., Bhavnani, N., Dougherty, J. A., Khan, M., Paruchuri, S. M., & Thodeti, C. K. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.790489 · Cited by 27

Targeting cancer-associated fibroblasts with hydroxyethyl starch nanomedicine boosts cancer therapy

Wang, C., Wang, H., Yang, H., Chen, X., Wang, Q., Li, Z., Zhang, Z., Guan, J., Yu, X., Yang, X., et al. (2023) · Nano Research · doi:10.1007/s12274-023-5394-7 · Cited by 27

Biomimetic nanotherapeutics for targeted drug delivery to glioblastoma multiforme

Lim, X. Y., Capinpin, S. M., Bolem, N., Foo, A. S. C., Yip, G. W., Kumar, A. P., & Teh, D. B. L. (2023) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10483 · Cited by 28

Physics of the tumor vasculature: Theory and experiment

Rieger, H., Fredrich, T., & Welter, M. (2016) · The European Physical Journal Plus · doi:10.1140/epjp/i2016-16031-9 · Cited by 26

Separation of Solid Stress From Interstitial Fluid Pressure in Pancreas Cancer Correlates With Collagen Area Fraction

Nieskoski, M. D., Marra, K. A., Gunn, J. R., Kanick, S. C., Doyley, M. M., Hasan, T. G., Pereira, S. P., Trembly, B. S., & Pogue, B. W. (2017) · Journal of Biomechanical Engineering · doi:10.1115/1.4036392 · Cited by 29

Effect of microvascular distribution and its density on interstitial fluid pressure in solid tumors: A computational model

Mohammadi, M., & Chen, P. (2015) · Microvascular Research · doi:10.1016/j.mvr.2015.06.001 · Cited by 27

CCL2 chemokine inhibition primes the tumor vasculature for improved nanomedicine delivery and efficacy

Möckel, D., Bartneck, M., Niemietz, P. M., Wagner, M., Ehling, J., Rama, E., Weiler, M., Gremse, F., Eulberg, D., Pola, R., et al. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.11.044 · Cited by 26

Identification of established and novel extracellular matrix components in glioblastoma as targets for angiogenesis and prognosis

Barbosa, L. C., Machado, G. C., Heringer, M., & Ferrer, V. P. (2024) · Neurogenetics · doi:10.1007/s10048-024-00763-x · Cited by 29

Bio responsive self-assembly of Au-miRNAs for targeted cancer theranostics

Cai, W., Feng, H., Yin, L., Wang, M., Jiang, X., Qin, Z., Liu, W., Li, C., Jiang, H., Weizmann, Y., et al. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.102740 · Cited by 26

Sparse Optimal Control of a Phase Field Tumor Model with Mechanical Effects

Garcke, H., Lam, K. F., & Signori, A. (2021) · SIAM Journal on Control and Optimization · doi:10.1137/20m1372093 · Cited by 25

Recent research and clinical progress of CTLA-4-based immunotherapy for breast cancer

Zhang, H., Mi, J., Qi, X., Cao, W., Song, C., Zhang, N., & Yuan, C. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1256360 · Cited by 27

Cyclopamine treatment disrupts extracellular matrix and alleviates solid stress to improve nanomedicine delivery for pancreatic cancer

Zhang, B., Wang, H., Jiang, T., Jin, K., Luo, Z., Shi, W., Mei, H., Wang, H., Hu, Y., Pang, Z., et al. (2018) · Journal of drug targeting · doi:10.1080/1061186x.2018.1452243 · Cited by 26

The Effects of Physical Exercise on Tumor Vasculature: Systematic Review and Meta-analysis

Esteves, M., Monteiro, M. P., & Duarte, J. A. (2021) · International Journal of Sports Medicine · doi:10.1055/a-1533-1876 · Cited by 26

Melanoma in the Eyes of Mechanobiology

Brás, M. M., Radmacher, M., Sousa, S. R., & Granja, P. L. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00054 · Cited by 25

Impact of a Desmoplastic Tumor Microenvironment for Colon Cancer Drug Sensitivity: A Study with 3D Chimeric Tumor Spheroids

Goudar, V. S., Koduri, M. P., Ta, Y. N., Chen, Y., Chu, L., Lu, L., & Tseng, F. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c18249 · Cited by 25

Breast cancer: miRNAs monitoring chemoresistance and systemic therapy

Singh, S., Saini, H., Sharma, A., Gupta, S., Huddar, V. G., & Tripathi, R. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1155254 · Cited by 25

Programing Assembling/Releasing Multifunctional miRNA Nanomedicine to Treat Prostate Cancer

Ma, D., Liu, H., Zhao, P., Li, Y., Zou, H., Zhao, X., Dai, H., Kong, X., & Liu, P. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b21707 · Cited by 25

Multiphysics modelling enhanced by imaging and artificial intelligence for personalised cancer nanomedicine: Foundations for clinical digital twins

Kashkooli, F. M., Bhandari, A., Gu, B., Kolios, M. C., Kohandel, M., & Zhan, W. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114138 · Cited by 28

Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model

Tehrani, M. H. H., Kashkooli, F. M., & Soltani, M. (2024) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2024.108050 · Cited by 24

Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits

Datta, M., Via, L. E., Dartois, V. A., Weiner, D. M., Zimmerman, M., Kaya, F., Walker, A. M., Fleegle, J. D., Raplee, I., McNinch, C., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2321336121 · Cited by 23

Bevacizumab radiosensitizes non-small cell lung cancer xenografts by inhibiting DNA double-strand break repair in endothelial cells

Gao, H., Xue, J., Zhou, L., Lan, J., He, J., Na, F., Yang, L., Deng, L., & Lü, Y. (2015) · Cancer Letters · doi:10.1016/j.canlet.2015.05.011 · Cited by 27

Cardiovascular fluid dynamics: a journey through our circulation

Menon, K., Hu, Z., & Marsden, A. L. (2024) · Flow · doi:10.1017/flo.2024.5 · Cited by 23

Multimodal Therapies against Pancreatic Ductal Adenocarcinoma: A Review on Synergistic Approaches toward Ultimate Nanomedicine Treatments

Conte, M., & Cauda, V. (2022) · Advanced Therapeutics · doi:10.1002/adtp.202200079 · Cited by 27

Spatiotemporal multi-scale modeling of radiopharmaceutical distributions in vascularized solid tumors

Shahvandi, M. K., Soltani, M., Kashkooli, F. M., Saboury, B., & Rahmim, A. (2022) · Scientific Reports · doi:10.1038/s41598-022-18723-6 · Cited by 24

Translational nanomedicine potentiates immunotherapy in sarcoma by normalizing the microenvironment

Mpekris, F., Panagi, M., Michael, C., Voutouri, C., Tsuchiya, M., Wagatsuma, C., Kinoh, H., Osada, A., Akinaga, S., Yoshida, S., et al. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.12.016 · Cited by 24

The emerging promise of tumour mechanobiology in cancer treatment

Papavassiliou, K. A., Basdra, E. K., & Papavassiliou, A. G. (2023) · European Journal of Cancer · doi:10.1016/j.ejca.2023.112938 · Cited by 23

Nanobubbles as ultrasound contrast agent for facilitating small cell lung cancer imaging

Wang, J., Zhou, X., Yan, J., Zheng, R., & Wang, W. (2017) · Oncotarget · doi:10.18632/oncotarget.18155 · Cited by 22

Coupling Microfluidic Platforms, Microfabrication, and Tissue Engineered Scaffolds to Investigate Tumor Cells Mechanobiology

Millet, M., Messaoud, R. B., Luthold, C., & Bordeleau, F. (2019) · Micromachines · doi:10.3390/mi10060418 · Cited by 24

Melanin-like nanoparticles loaded with an angiotensin antagonist for an improved photothermal cancer therapy

Zhou, Z., Yang, Y., Zhang, Q., & Cheng, Y. (2020) · Biomaterials Science · doi:10.1039/c9bm01843c · Cited by 22

Implantable fibrous scaffold with hierarchical microstructure for the ‘on-site’ synergistic cancer therapy

Fu, Y., Cen, D., Zhang, T., Jiang, S., Wang, Y., Cai, X., Li, X., & Han, G. (2020) · Chemical Engineering Journal · doi:10.1016/j.cej.2020.126204 · Cited by 22

How Nanoparticles Interact with Cancer Cells

Syed, A. M., & Chan, W. C. W. (2015) · Cancer treatment and research · doi:10.1007/978-3-319-16555-4_10 · Cited by 23

Increasing the tumour targeting of antitumour drugs through anlotinib-mediated modulation of the extracellular matrix and the RhoA/ROCK signalling pathway

Han, X., Liu, J., Zhang, Y., Tse, E., Yu, Q., Yu, L., Ma, Y., & Zheng, L. (2024) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2024.100984 · Cited by 21

Remodeling of extracellular matrix due to solid stress accumulation during tumor growth

Pirentis, A. P., Polydorou, C., Papageorgis, P., Voutouri, C., Mpekris, F., & Stylianopoulos, T. (2015) · Connective Tissue Research · doi:10.3109/03008207.2015.1047929 · Cited by 21

Stress alleviation strategy in cancer treatment: Insights from a mathematical model

Mpekris, F., Voutouri, C., Papageorgis, P., & Stylianopoulos, T. (2018) · ZAMM ‐ Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik · doi:10.1002/zamm.201700270 · Cited by 21

Scenario and future prospects of microRNAs in gastric cancer: A review.

Bhat, S. A., Majid, S., & Rehman, M. U. (2019) · PubMed Central · doi:10.22038/ijbms.2019.32399.7765 · Cited by 21

Estimation of Vascular Permeability in Irregularly Shaped Cancers Using Ultrasound Poroelastography

Islam, M. T., Tasciotti, E., & Righetti, R. (2019) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2019.2929134 · Cited by 21

MicroRNAs as therapeutic targets in breast cancer metastasis

Pouya, F. D., Rasmi, Y., Gazouli, M., Zografos, E., & Nemati, M. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-021-00999-2 · Cited by 20

Towards Immunotherapy-Induced Normalization of the Tumor Microenvironment

Melo, V. A., Bremer, E., & Martin, J. D. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.908389 · Cited by 20

Computational simulations of tumor growth and treatment response: Benefits of high-frequency, low-dose drug regimens and concurrent vascular normalization

Nikmaneshi, M. R., Jain, R. K., & Munn, L. L. (2023) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1011131 · Cited by 22

The influence of anisotropic growth and geometry on the stress of solid tumors

Ramírez‐Torres, A., Rodrı́guez-Ramos, R., Merodio, J., Penta, R., Bravo‐Castillero, J., Guinovart-Dı́az, R., Sabina, F. J., García‐Reimbert, C., Sevostianov, I., & Conci, A. (2017) · International Journal of Engineering Science · doi:10.1016/j.ijengsci.2017.06.011 · Cited by 20

Targeting angiogenesis: Lessons from 25 years of normalizing tumor vasculature

Subudhi, S., Lee, S., & Jain, R. K. (2026) · Cell · doi:10.1016/j.cell.2026.03.016 · Cited by 29

A New Imaging Platform for Visualizing Biological Effects of Non-Invasive Radiofrequency Electric-Field Cancer Hyperthermia

Corr, S. J., Shamsudeen, S., Vergara, L. A., Ho, J. C.-S., Ware, M. J., Keshishian, V., Yokoi, K., Savage, D. J., Meraz, I. M., Kaluarachchi, W. D., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136382 · Cited by 19

Intra-tumor distribution of PEGylated liposome upon repeated injection: No possession by prior dose

Nakamura, H., Lila, A. S. A., Nishio, M., Tanaka, M., Ando, H., Kiwada, H., & Ishida, T. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.11.002 · Cited by 19

Brain tumor vessels—a barrier for drug delivery

Hempel, C., Johnsen, K. B., Kostrikov, S., Hamerlik, P., & Andresen, T. L. (2020) · Cancer and Metastasis Reviews · doi:10.1007/s10555-020-09877-8 · Cited by 18

Lymphatic uptake of biotherapeutics through a 3D hybrid discrete-continuum vessel network in the skin tissue

Han, D., Li, C., Araimdeh, S., Sree, V. D., Rahimi, E., Tepole, A. B., & Ardekani, A. M. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.12.045 · Cited by 19

Mathematical modeling of intratumoral immunotherapy yields strategies to improve the treatment outcomes

Harkos, C., Stylianopoulos, T., & Jain, R. K. (2023) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1011740 · Cited by 19

Engineering nanoparticles to tackle tumor barriers

Li, J.-X., Huang, Q., Zhang, J., & Du, J. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb00967a · Cited by 19

Challenges and Perspectives for Immunotherapy in Adenocarcinoma of the Pancreas

Kieler, M., Unseld, M., Bianconi, D., & Prager, G. W. (2018) · Pancreas · doi:10.1097/mpa.0000000000000970 · Cited by 18

Bioengineered Ionic Liquid for Catheter‐Directed Tissue Ablation, Drug Delivery, and Embolization

Keum, H., Albadawi, H., Zhang, Z., Graf, E. H., dos Santos, P. R., Gunduz, S. G., & Öklü, R. (2024) · Advanced Materials · doi:10.1002/adma.202309412 · Cited by 18

Time-dependent pretreatment with bevacuzimab increases tumor specific uptake of cetuximab in preclinical oral cavity cancer studies

Chung, T. K., Warram, J. M., Day, K. E., Hartman, Y. E., & Rosenthal, E. L. (2015) · Cancer Biology & Therapy · doi:10.1080/15384047.2015.1016664 · Cited by 18

Formulation and physiologic factors affecting the pharmacology of carrier-mediated anticancer agents

Lucas, A. T., Madden, A. J., & Zamboni, W. C. (2015) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425255.2015.1057496 · Cited by 18

Polyester nanoparticles delivering chemotherapeutics: Learning from the past and looking to the future to enhance their clinical impact in tumor therapy

Longobardi, G., Moore, T. L., Conte, C., Ungaro, F., Satchi‐Fainaro, R., & Quaglia, F. (2024) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1990 · Cited by 19

Strategies of targeting pathological stroma for enhanced antitumor therapies

Zhu, Y., Yu, F., Tan, Y., Yuan, H., & Hu, F. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.104401 · Cited by 16

Anticoagulation therapy promotes the tumor immune-microenvironment and potentiates the efficacy of immunotherapy by alleviating hypoxia

Choi, J. U., Lee, N. K., Seo, H., Chung, S. W., Al-Hilal, T. A., Park, S. J., Kweon, S., Min, N., Kim, S. K., Ahn, S.-H., et al. (2021) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2021-002332 · Cited by 17

Ultrasound Combined With Microbubbles Increase the Delivery of Doxorubicin by Reducing the Interstitial Fluid Pressure

Xiao, N., Liu, J., Liao, L., Sun, J., Jin, W., & Shu, X. (2018) · Ultrasound Quarterly · doi:10.1097/ruq.0000000000000381 · Cited by 18

The use of MR perfusion in assessing the efficacy of treatment for malignant brain tumors

Александровна, Р. В., Sergeev, N. I., Padalko, V. V., Kotlyarov, P. M., & Solodkiy, V. А. (2019) · Burdenko s Journal of Neurosurgery · doi:10.17116/neiro201983041113 · Cited by 16

Multiphoton Phosphorescence Quenching Microscopy Reveals Kinetics of Tumor Oxygenation during Antiangiogenesis and Angiotensin Signaling Inhibition

Martin, J. D., Lanning, R. M., Chauhan, V. P., Martin, M. R., Mousa, A. S., Kamoun, W. S., Han, H., Lee, H., Stylianopoulos, T., Bawendi, M. G., et al. (2022) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-22-0486 · Cited by 16

Predictive Design and Analysis of Drug Transport by Multiscale Computational Models Under Uncertainty

Akalın, A. A., Dedekargınoğlu, B., Choi, S. R., Han, B., & Özçelikkale, A. (2022) · Pharmaceutical Research · doi:10.1007/s11095-022-03298-8 · Cited by 16

Sononeoperfusion effect by ultrasound and microbubble promotes nitric oxide release to alleviate hypoxia in a mouse MC38 tumor model

Zhang, Y., Zhang, J., Luo, T., Cai, Z., Yang, G., Li, H., Wei, J., Zhu, Q. N., Li, P., Dong, X., et al. (2023) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2023.106619 · Cited by 16

Dose-Specific Intratumoral GM-CSF Modulates Breast Tumor Oxygenation and Antitumor Immunity

Mihalik, N. E., Steinberger, K. J., Stevens, A. M., Bobko, A. A., Hoblitzell, E. H., Tseytlin, O., Akhter, H., Dziadowicz, S. A., Wang, L., O’Connell, R. C., et al. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2300326 · Cited by 18

Pharmacokinetics and Efficacy of doxorubicin-loaded Plant Virus Nanoparticles in Preclinical Models of Cancer

Madden, A. J., Oberhardt, B. J., Lockney, D. M., Santos, C., Vennam, P., Arney, D., Franzen, S., Lommel, S. A., Miller, C. R., Gehrig, P. A., et al. (2017) · Nanomedicine · doi:10.2217/nnm-2016-0421 · Cited by 16

Imaging methods to evaluate tumor microenvironment factors affecting nanoparticle drug delivery and antitumor response

Moody, A. S., Dayton, P. A., & Zamboni, W. C. (2021) · Cancer Drug Resistance · doi:10.20517/cdr.2020.94 · Cited by 18

Low-dose X-ray irradiation combined with FAK inhibitors improves the immune microenvironment and confers sensitivity to radiotherapy in pancreatic cancer

Chen, H., Tu, W., Lu, Y., Zhang, Y., Xu, Y., Chen, X., Zhu, M., & Liu, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113114 · Cited by 16

Finite Element Modeling of Avascular Tumor Growth Using a Stress-Driven Model

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ATP promotes immunosuppressive capacities of mesenchymal stromal cells by enhancing the expression of indoleamine dioxygenase

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