The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver
Open accessAbstract
Significance: Comprehending the responses of organisms to pollutants by a systems-based approach allows characterization of molecular events and the cellular pathways that have been perturbed. However, mapping only adverse outcomes of a toxicant in an organism falls short of describing the defense response that is mounted to maintain homeostasis and resistance to the toxic insult. Our study provides the understanding of molecular mechanisms of algae in response to silver, which in turn indicates how the algae might behave in a silver contamination scenario. We have used complementary information obtained from the transcriptome, proteome, and physiology to gain mechanistic insights into the responses of Chlamydomonas reinhardtii . We show here the importance of stress and adaptive responses, especially at sublethal concentrations of pollutant.
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Cites
Global quantification of mammalian gene expression control
Schwanhäusser, B., Busse, D., Li, N., Dittmar, G., Schuchhardt, J., Wolf, J., Chen, W., & Selbach, M. (2011) · Nature · doi:10.1038/nature10098 · Cited by 6,566 · cited 2×
“The reason for the discrepancy is that proteins involved in cell proliferation are unstable and have short half-lives (23).”
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Cited by
Wang, L., Zhang, T., Li, P., Huang, W., Tang, J., Wang, P., Liu, J., Yuan, Q., Bai, R., Li, B., et al. (2015) · ACS Nano · doi:10.1021/acsnano.5b02483 · Cited by 290
Mixtures of Chemical Pollutants at European Legislation Safety Concentrations: How Safe Are They?
Carvalho, R. N., Arukwe, A., Ait-Aissa, S., Bado-Nilles, A., Balzamo, S., Baun, A., Belkin, S., Blaha, L., Brion, F., Conti, D., et al. (2014) · Toxicological Sciences · doi:10.1093/toxsci/kfu118 · Cited by 133
Self-citationMao, F., He, Y., & Gin, K. (2018) · Toxics · doi:10.3390/toxics6010008 · Cited by 31
Metadata
- Authors
- Pillai, S., Behra, R., Nestler, H., Suter, M. J.-F., Sigg, L., & Schirmer, K.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2014-02-18
- Volume
- 111
- Issue
- 9
- Pages
- 3490-3495
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2146247723
- Cited by
- 159
- References
- 1
- FWCI
- 12.90
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver. https://app.cochat.ai/papers/10.1073/pnas.1319388111
- The paper
- Pillai, S., Behra, R., Nestler, H., Suter, M. J.-F., Sigg, L., & Schirmer, K. (2014). Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1319388111
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
