Fred Sanger: A memorial tribute
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Frederick Sanger determined the amino acid sequences of the A and B chains of insulin; by 1955 he demonstrated the position of the two disulfide bonds linking the A and B chains and the intrachain disulfide bond within the A chain.
“In the early 1950s, Frederick Sanger determined the amino acid sequences of the A and B chains of insulin87–90. By 1955, he would demonstrate the position of the two disulfide bonds linking the A and B chains and the intrachain disulfide bond within the A chain, and in 1958, he was awarded the Nobel Prize in Chemistry91–93.”
From 100 years of insulin: celebrating the past, present and future of diabetes therapy (2021) · cites this paper as [91]
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100 years of insulin: celebrating the past, present and future of diabetes therapy
Sims, E. K., Carr, A. L. J., Oram, R. A., DiMeglio, L. A., & Evans-Molina, C. (2021) · Nature Medicine · doi:10.1038/s41591-021-01418-2 · Cited by 270 · see citing works
- Authors
- Berg, P.
- Affiliations
- Stanford Medicine (US)
- Corresponding author
- Berg, Paul
- ORCID
- Berg, Paul
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2014-01-20
- Volume
- 111
- Issue
- 3
- Pages
- 883-884
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC3903207
- OpenAlex
- W2094608897
- Cited by
- 7
- References
- 0
- Citations by year
- 2023: 2 · 2022: 1 · 2021: 3 · 2019: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Arts and Humanities › History and Philosophy of Science › History of Science and Medicine
- Social Sciences › Arts and Humanities › History › Biographical and Historical Analysis
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy and History of Science
- Keywords
- DNA sequencing, protein sequencing, scientific legacy
- MeSH terms
- Chemistry, United Kingdom, Humans, Insulin, Nobel Prize, Sequence Analysis, Genomics, History, 20th Century
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