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Cited by 274

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Acute myeloid leukemias with reciprocal rearrangements can be distinguished by specific gene expression profiles

Open access
Schoch, Claudia, Kohlmann, Alexander, Schnittger, Susanne, Brors, Benedikt, Dugas, Martin, Mergenthaler, Susanne, Kern, Wolfgang, Hiddemann, Wolfgang, Eils, Roland, Haferlach, Torsten·2002·Proceedings of the National Academy of Sciences

Abstract

Acute myeloid leukemia (AML) is a heterogeneous group of genetically defined diseases. Their classification is important with regard to prognosis and treatment. We performed microarray analyses for gene expression profiling on bone marrow samples of 37 patients with newly diagnosed AML. All cases had either of the distinct subtypes AML M2 with t(8;21), AML M3 or M3v with t(15;17), or AML M4eo with inv(16). Diagnosis was established by cytomorphology, cytogenetics, fluorescence in situ hybridization, and reverse transcriptase–PCR in every sample. By using two different strategies for microarray data analyses, this study revealed a unique correlation between AML-specific cytogenetic aberrations and gene expression profiles.

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Crossref · 10.1073/pnas.142103599

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Metadata

Authors
Schoch, C., Kohlmann, A., Schnittger, S., Brors, B., Dugas, M., Mergenthaler, S., Kern, W., Hiddemann, W., Eils, R., & Haferlach, T.
Venue
Proceedings of the National Academy of Sciences
Published
2002-07-08
Volume
99
Issue
15
Pages
10008-10013
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2138069312
Cited by
274
References
2
FWCI
14.59
Type
journal article
Language
en
Open access
green

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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