The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
DNA detection using water-soluble conjugated polymers and peptide nucleic acid probes
Open accessAbstract
The light-harvesting properties of cationic conjugated polymers are used to sensitize the emission of a dye on a specific peptide nucleic acid (PNA) sequence for the purpose of homogeneous, “real-time” DNA detection. Signal transduction is controlled by hybridization of the neutral PNA probe and the negative DNA target. Electrostatic interactions bring the hybrid complex and cationic polymer within distances required for Förster energy transfer. Conjugated polymer excitation provides fluorescein emission >25 times higher than that obtained by exciting the dye, allowing detection of target DNA at concentrations of 10 pM with a standard fluorometer. A simple and highly sensitive assay with optical amplification that uses the improved hybridization behavior of PNA/DNA complexes is thus demonstrated.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules
Egholm, M., Buchardt, O., Christensen, L., Behrens, C., Freier, S. M., Driver, D. A., Berg, R. H., Kim, S. K., Norden, B., & Nielsen, P. E. (1993) · Nature · doi:10.1038/365566a0 · Cited by 2,079
Cited by
Conjugated Polyelectrolytes: Synthesis, Photophysics, and Applications
Jiang, H., Taranekar, P., Reynolds, J. R., & Schanze, K. S. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200805456 · Cited by 734
Metadata
- Authors
- Gaylord, B. S., Heeger, A. J., & Bazan, G. C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2002-08-07
- Volume
- 99
- Issue
- 17
- Pages
- 10954-10957
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2132235135
- Cited by
- 605
- References
- 1
- FWCI
- 8.21
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: DNA detection using water-soluble conjugated polymers and peptide nucleic acid probes. https://app.cochat.ai/papers/10.1073/pnas.162375999
- The paper
- Gaylord, B. S., Heeger, A. J., & Bazan, G. C. (2002). DNA detection using water-soluble conjugated polymers and peptide nucleic acid probes. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.162375999
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
