The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags
Open accessAbstract
Understanding biological systems and the roles of their constituents is facilitated by the ability to make quantitative, sensitive, and comprehensive measurements of how their proteome changes, e.g., in response to environmental perturbations. To this end, we have developed a high-throughput methodology to characterize an organism's dynamic proteome based on the combination of global enzymatic digestion, high-resolution liquid chromatographic separations, and analysis by Fourier transform ion cyclotron resonance mass spectrometry. The peptides produced serve as accurate mass tags for the proteins and have been used to identify with high confidence >61% of the predicted proteome for the ionizing radiation-resistant bacterium Deinococcus radiodurans . This fraction represents the broadest proteome coverage for any organism to date and includes 715 proteins previously annotated as either hypothetical or conserved hypothetical.
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Cites
The sequence of the human genome
Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909
Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
Gygi, S. P., Rist, B., Gerber, S. A., Turecek, F., Gelb, M. H., & Aebersold, R. (1999) · Nature Biotechnology · doi:10.1038/13690 · Cited by 4,683
Sharp, P. M., & Li, W.-H. (1987) · Nucleic Acids Research · doi:10.1093/nar/15.3.1281 · Cited by 3,992
Mattimore, V, & Battista, J. R. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.3.633-637.1996 · Cited by 687
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Cited by
Mass spectrometry-based proteomics
Aebersold, R., & Mann, M. (2003) · Nature · doi:10.1038/nature01511 · Cited by 6,955
Anderson, N. L., & Anderson, N. G. (2002) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r200007-mcp200 · Cited by 4,414
Oxidative Stress Resistance in Deinococcus radiodurans
Slade, D., & Radman, M. (2011) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00015-10 · Cited by 761
Identification of Proteins in Human Cytomegalovirus (HCMV) Particles: the HCMV Proteome
Varnum, S. M., Streblow, D. N., Monroe, M. E., Smith, P., Auberry, K. J., Paša-Tolić, L., Wang, D., Camp, D. G., Rodland, K., Wiley, S., et al. (2004) · Journal of Virology · doi:10.1128/jvi.78.20.10960-10966.2004 · Cited by 598
Self-citationGurvich, O. L., Baranov, P. V., Zhou, J., Hammer, A. W., Gesteland, R. F., & Atkins, J. F. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg561 · Cited by 87
Metadata
- Authors
- Lipton, M. S., Paša-Tolić, L., Anderson, G. A., Anderson, D. J., Auberry, D. L., Battista, J. R., Daly, M. J., Fredrickson, J., Hixson, K. K., Kostandarithes, H., Masselon, C., Markillie, L. M., Moore, R. J., Romine, M. F., Shen, Y., Stritmatter, E., Tolić, N., Udseth, H. R., Venkateswaran, A., Wong, K.-K., Zhao, R., & Smith, R. D.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2002-08-12
- Volume
- 99
- Issue
- 17
- Pages
- 11049-11054
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2118103468
- Cited by
- 392
- References
- 4
- FWCI
- 23.29
- Type
- journal article
- Language
- en
- Open access
- green
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- Lipton, M. S., Paša-Tolić, L., Anderson, G. A., Anderson, D. J., Auberry, D. L., Battista, J. R., Daly, M. J., Fredrickson, J., Hixson, K. K., Kostandarithes, H., Masselon, C., Markillie, L. M., Moore, R. J., Romine, M. F., Shen, Y., Stritmatter, E., Tolić, N., Udseth, H. R., Venkateswaran, A., . . . Smith, R. D. (2002). Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.172170199
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
