Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss

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1. Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease β‐amyloid
   Kevin Jeffrey Barnham, Fredrik Hæffner, Giuseppe D. Ciccotosto, Cyril C. Curtain, Deborah J. Tew, Christine Mavros, Konrad T. Beyreuther, Darryl Carrington, Colin Louis Masters, Robert A. Cherny et al. · 2004 · The FASEB Journal
2. Intracellular Aβ and cognitive deficits precede β-amyloid deposition in transgenic arcAβ mice
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4. Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research
   Asad Jan, Dean M. Hartley, Hilal Ahmed Lashuel · 2010 · Nature Protocols
5. A role for heme in Alzheimer's disease: Heme binds amyloid β and has altered metabolism
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6. Intracellular accumulation of amyloid-beta – a predictor for synaptic dysfunction and neuron loss in Alzheimer’s disease
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7. Targeting Amyloid-β Peptide (Aβ) Oligomers by Passive Immunization with a Conformation-selective Monoclonal Antibody Improves Learning and Memory in Aβ Precursor Protein (APP) Transgenic Mice
   Edward B. Lee, Lewis Z. Leng, Bin Zhang, Linda K. Kwong, John Q. Trojanowski, Ted G. Abel, Virginia M.‐Y. Lee · 2005 · Journal of Biological Chemistry
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   Zina Kroner · 2009 · PubMed
9. The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non‐human primate model of Alzheimer's disease
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13. Neurogenic Effect of  -Amyloid Peptide in the Development of Neural Stem Cells
    Lopez-Toledano, M. A. · 2004 · Journal of Neuroscience
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    Xudong Huang, Craig Atwood, Robert D. Moir, Mariana A. Hartshorn, Rudolph E. Tanzi, Ashley Ian Bush · 2004 · JBIC Journal of Biological Inorganic Chemistry
15. Current and Emerging Drug Treatment Options for Alzheimerʼs Disease
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16. Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death
    Resende, R., Ferreiro, E., Pereira, C., Resende de Oliveira, C. · 2008 · Neuroscience
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    Deshpande, Atul, Kawai, Hideki, Metherate, Raju, Glabe, Charles G., Busciglio, Jorge · 2009 · The Journal of Neuroscience
19. Alzheimer's Disease-Like Pathology Induced by Amyloid-β Oligomers in Nonhuman Primates
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    G. Lace, George M. Savva, G. Forster, Rohan de Silva, Carol Brayne, Fiona E. Matthews, J. J. Barclay, L. Dakin, Paul G. Ince, Stephen B. Wharton · 2009 · Brain
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    Iris A. Mastrangelo, Mahiuddin Ahmed, Takeshi Sato, Wei Liu, Chengpu Wang, Paul V. C. Hough, Steven O. Smith · 2006 · Journal of Molecular Biology
22. The PI3K/Akt signaling axis in Alzheimer’s disease: a valuable target to stimulate or suppress?
    Elham Razani, Atieh Pourbagheri‐Sigaroodi, Ava Safaroghli‐Azar, Anahita Zoghi, Mahsa Shanaki Bavarsad, Davood Bashash · 2021 · Cell Stress and Chaperones
23. Animal models in the drug discovery pipeline for Alzheimer's disease
    Debby Van Dam, Peter Paul De Deyn · 2011 · British Journal of Pharmacology
24. The Polyphenol Oleuropein Aglycone Protects TgCRND8 Mice against Aß Plaque Pathology
    Cristina Grossi, Stefania Rigacci, Stefano Ambrosini, Teresa Ed Dami, Ilaria Luccarini, Chiara Traini, Paola Failli, Andrea Berti, Fiorella Casamenti, Massimo Stefani · 2013 · PLoS ONE
25. Inhibition of insulin amyloid formation by small stress molecules
    Anubhav Arora, Chanki Ha, Chan Beum Park · 2004 · FEBS Letters
26. Congo red and thioflavin‐T analogs detect Aβ oligomers
    Izumi Maezawa, Hyun‐Seok Hong, Ruiwu Liu, Chun‐Yi Wu, R. Holland Cheng, Mei‐Ping Kung, Hank F. Kung, Kit S. Lam, Salvatore Oddo, Frank M. LaFerla et al. · 2007 · Journal of Neurochemistry
27. Peripheral Aβ subspecies as risk biomarkers of Alzheimer's disease
    Schupf, Nicole, Tang, Ming X., Fukuyama, Hide, Manly, Jennifer, Andrews, Howard, Mehta, Pankaj, Ravetch, Jeffery, Mayeux, Richard · 2008 · Proceedings of the National Academy of Sciences
28. Amyloid β-Protein Toxicity and the Pathogenesis of Alzheimer Disease
    Bruce A. Yankner, Tao Lu · 2008 · Journal of Biological Chemistry
29. Amyloid β peptide oligomers directly activate NMDA receptors
    Laura Texidó, Mireia Martı́n-Satué, Elena M Alberdi, Carles Solsona, Carlos Matute · 2011 · Cell Calcium
30. The Interplay of Catalysis and Toxicity by Amyloid Intermediates on Lipid Bilayers: Insights from Type II Diabetes
    James A. Hebda, Andrew D. Miranker · 2009 · Annual Review of Biophysics
31. Neurotoxic protein oligomers — what you see is not always what you get
    Bitan, Gal, Fradinger, Erica A, Spring, Sean M, Teplow, David B · 2005 · Amyloid
32. Progressive accumulation of amyloid‐ β oligomers in Alzheimer’s disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins
    Emiley Pham, Leslie A. Crews, Kiren K. Ubhi, Lawrence A. Hansen, Anthony Adame, Anna E. Cartier, David P. Salmon, Douglas R Galasko, Sarah Michael, Jeffrey N. Savas et al. · 2010 · FEBS Journal
33. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death
    Wang, Xiaonan, Hu, Xuejun, Yang, Yang, Takata, Toshihiro, Sakurai, Takashi · 2016 · Brain Research
34. Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils
    Gernot Habicht, Christian Haupt, Ralf P. Friedrich, Peter Hortschansky, Carsten Sachse, Jessica Meinhardt, Karin Wieligmann, Gerald P. Gellermann, Michael Brodhun, Jürgen Götz et al. · 2007 · Proceedings of the National Academy of Sciences
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    Shiyong Peng, Diego J. Garzon, Monica Marchese, William L. Klein, Stephen D. Ginsberg, Beverly M. Francis, Howard T.J. Mount, Elliott Jay Mufson, Ahmad Salehi, Margaret L. Fahnestock · 2009 · Journal of Neuroscience
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    de Godoy, Mariana A., Saraiva, Leonardo M., de Carvalho, Luiza R.P., Vasconcelos-dos-Santos, Andreia, Beiral, Hellen J.V., Ramos, Alane Bernardo, Silva, Livian R. de Paula, Leal, Renata B., Monteiro, Victor H.S., Braga, Carolina V. et al. · 2018 · Journal of Biological Chemistry
37. Meat‐Adaptive Genes and the Evolution of Slower Aging in Humans
    Caleb E. Finch, Craig B. Stanford · 2004 · The Quarterly Review of Biology
38. Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes
    Hong, Soyon, Ostaszewski, Beth L., Yang, Ting, O’Malley, Tiernan T., Jin, Ming, Yanagisawa, Katsuhiko, Li, Shaomin, Bartels, Tim, Selkoe, Dennis J. · 2014 · Neuron
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    I-Hsien Chou, Melodie E. Benford, Hope T. Beier, Gerard L. Coté, Miao Wang, Nan Jing, Jun Kameoka, Theresa A. Good · 2008 · Nano Letters
40. Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway
    Catherine Malaplate, Sabrina Florent‐Béchard, Ihsen Youssef, Violette Koziel, Isabelle Sponne, Badreddine Kriem, Brigitte Leininger‐Muller, J L Olivier, Thierry Oster, Thierry Pillot · 2006 · Neurobiology of Disease
41. Cell number changes in Alzheimer's disease relate to dementia, not to plaques and tangles
    Carlos Humberto Andrade-Moraes, Ana Virgínia de Oliveira-Pinto, Emily Castro-Fonseca, C. G. da Silva, Daniel Menezes Guimarães, Diego Szczupak, D. R. Parente-Bruno, Ludmila R.B. Carvalho, Lívia Polichiso, Bruna Valério‐Gomes et al. · 2013 · Brain
42. Structural Reorganisation and Potential Toxicity of Oligomeric Species Formed during the Assembly of Amyloid Fibrils
    Mookyung Cheon, Iksoo Chang, Sandipan Mohanty, Leila M. Luheshi, Christopher Martin Dobson, Michele Vendruscolo, Giorgio Favrin · 2007 · PLoS Computational Biology
43. Selection of DNA Aptamers That Recognize α-Synuclein Oligomers Using a Competitive Screening Method
    Kaori Tsukakoshi, Koichi Abe, Koji Sode, Kazunori Ikebukuro · 2012 · Analytical Chemistry
44. AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice
    Chang, Eric H., Savage, Mary J., Flood, Dorothy G., Thomas, Justin M., Levy, Robert B., Mahadomrongkul, Veeravan, Shirao, Tomoaki, Aoki, Chiye, Huerta, Patricio T. · 2006 · Proceedings of the National Academy of Sciences
45. Lysozyme Amyloid Oligomers and Fibrils Induce Cellular Death via Different Apoptotic/Necrotic Pathways
    Anna L. Gharibyan, Vladimir Zamotin, Kiran Yanamandra, O. S. Moskaleva, Boris A. Margulis, Irina A. Kostanyan, Ludmilla A. Morozova‐Roche · 2006 · Journal of Molecular Biology
46. Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer’s Disease
    Cioffi, Federica, Adam, Rayan Hassan Ibrahim, Broersen, Kerensa · 2019 · Journal of Alzheimer s Disease
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    Jeffrey A. Fein, Sophie Sokolow, Carol A. Miller, Harry V. Vinters, Fusheng Yang, Gregory M. Cole, Karen H. Gylys · 2008 · American Journal Of Pathology
48. Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm
    Ratnesh Lal, Hai Lin, Arjan Pieter Quist · 2007 · Biochimica et Biophysica Acta (BBA) - Biomembranes
49. Bifunctional Compounds for Controlling Metal-Mediated Aggregation of the Aβ₄₂Peptide
    Sharma, Anuj K., Pavlova, Stephanie T., Kim, Jaekwang, Finkelstein, Darren, Hawco, Nicholas J., Rath, Nigam P., Kim, Jungsu, Mirica, Liviu M. · 2012 · Journal of the American Chemical Society
50. Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect?
    Dennis W. Dickson · 2004 · Journal of Clinical Investigation
51. An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity
    Elisabete B. Ferreiro, Rosa Resende, Rui O. Costa, Catarina Resende Oliveira, Cláudia Pereira · 2006 · Neurobiology of Disease
52. Adverse Stress, Hippocampal Networks, and Alzheimer’s Disease
    Sarah M. Rothman, Mark P. Mattson · 2009 · NeuroMolecular Medicine
53. CSF Biomarkers for Alzheimer's Disease Diagnosis
    Anoop Arunagiri, Pradeep Kumar Singh, Reeba Susan Jacob, Samir Kumar Maji · 2010 · International Journal of Alzheimer s Disease
54. Ibuprofen reduces Aβ, hyperphosphorylated tau and memory deficits in Alzheimer mice
    Ann Carolyn McKee, Isabel Carreras, Lokman Hossain, Hoon Ryu, William L. Klein, Salvatore Oddo, Frank M. LaFerla, Bruce G. Jenkins, Neil W. Kowall, Alpaslan Dedeoglu · 2008 · Brain Research
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    Fernanda G. De Felice, Marcelo N. N. Vieira, Leonardo Martins Saraiva, José Daniel Figueroa‐Villar, José Garcia-Abreu, Roy Liu, Lei Chang, W L Klein, Sergio Teixeira Ferreira · 2004 · The FASEB Journal
56. Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease
    Kirsten L. Viola, James Sbarboro, Ruchi Sureka, Mrinmoy De, Maira Assunção Bicca, Jane Wang, Shaleen R. Vasavada, Sreyesh Satpathy, Summer Wu, Hrushikesh M. Joshi et al. · 2014 · Nature Nanotechnology
57. Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its parts
    Matthias Gralle, Sergio Teixeira Ferreira · 2007 · Progress in Neurobiology
58. Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer’s disease immunotherapeutics
    Goure, William F, Krafft, Grant A, Jerecic, Jasna, Hefti, Franz · 2014 · Alzheimer's Research & Therapy
59. Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model
    Sebastián Jiménez, M. Torres, Marisa Vizuete, Raquel Maria Sanchez-Varo, Elisabeth Sánchez‐Mejías, Laura Trujillo‐Estrada, Irene Carmona‐Cuenca, Cristina Caballero, Diego Ruano, Antonia Gutiérrez et al. · 2011 · Journal of Biological Chemistry
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    Charles C. Glabe · 2006 · Springer eBooks
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    Mary J. Savage, Juliya Kalinina, Abigail L. Wolfe, Katherine Tugusheva, Rachel Korn, Tanesha Cash-Mason, Jill W. Maxwell, Nathan Galen Hatcher, Sharie J. Haugabook, Guoxin Wu et al. · 2014 · Journal of Neuroscience
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    Olivier C. Maes, Suying Xu, Bo Yu, Howard Mark Chertkow, Eugenia Wang, Hyman M. Schipper · 2006 · Neurobiology of Aging
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67. Preliminary studies and potential applications of localized surface plasmon resonance spectroscopy in medical diagnostics
    Amanda J. Haes, Richard P. Van Duyne · 2004 · Expert Review of Molecular Diagnostics
68. Impaired insulin signalling and allostatic load in Alzheimer disease
    Fernanda G. De Felice, Rafaella Araujo Gonçalves, Sergio Teixeira Ferreira · 2022 · Nature reviews. Neuroscience
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    Weiqi Hong, Fei Mo, Ziqi Zhang, Mengyuan Huang, Xiawei Wei · 2020 · Frontiers in Cell and Developmental Biology
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    Vijay Kumar, Neha Sami, Tara Kashav, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan · 2016 · European Journal of Medicinal Chemistry
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    Pereira Diniz, Luan, Tortelli, Vanessa, Matias, Isadora, Morgado, Juliana, Bérgamo Araujo, Ana Paula, Melo, Helen M., Seixas da Silva, Gisele S., Alves-Leon, Soniza V., de Souza, Jorge M., Ferreira, Sergio T. et al. · 2017 · The Journal of Neuroscience
73. Insight into Amyloid Structure Using Chemical Probes
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76. Cytoskeletal pathologies of Alzheimer disease
    James R. Bamburg, George S. Bloom · 2009 · Cell Motility and the Cytoskeleton
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    Sadowski, Martin J., Pankiewicz, Joanna, Scholtzova, Henrieta, Mehta, Pankaj D., Prelli, Frances, Quartermain, David, Wisniewski, Thomas · 2006 · Proceedings of the National Academy of Sciences
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91. Insulin Receptor Dysfunction Impairs Cellular Clearance of Neurotoxic Oligomeric Aβ
    Zhao, Wei-Qin, Lacor, Pascale N., Chen, Hui, Lambert, Mary P., Quon, Michael J., Krafft, Grant A., Klein, William L. · 2009 · Journal of Biological Chemistry
92. Conformation-dependent antibodies target diseases of protein misfolding
    Charles C. Glabe · 2004 · Trends in Biochemical Sciences
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    Ronald Soong, Jeffrey Brender, Peter M. Macdonald, Ayyalusamy Ramamoorthy · 2009 · Journal of the American Chemical Society
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    Khyati Mittal, Deepshikha Pande Katare · 2016 · Diabetes & Metabolic Syndrome Clinical Research & Reviews
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    Min Jeong Wang, SangHak Yi, Jee-young Han, Young Ho Park, Jae‐Won Jang, In Kook Chun, Sang Eun Kim, Byoung Sub Lee, Gwang Je Kim, Ji Sun Yu et al. · 2017 · Alzheimer s Research & Therapy
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98. Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
    Ryan Limbocker, Sean Chia, Francesco Simone Ruggeri, Michele Perni, Roberta Cascella, Gabriella T. Heller, Georg Meisl, Benedetta Mannini, Johnny Habchi, Thomas C. T. Michaels et al. · 2019 · Nature Communications
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