The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary
Open accessAbstract
Significance: This paper improves knowledge of the somatic and germ cells of the developing mouse ovary that assemble into ovarian follicles, by determining cellular gene expression, and tracing lineage relationships. The study covers the last week of fetal development through the first five days of postnatal development. During this time, many critically important processes take place, including sex determination, follicle assembly, and the initial events of meiosis. We report expression differences between pregranulosa cells of wave 1 follicles that function at puberty and wave 2 follicles that sustain fertility. These studies illuminate ovarian somatic cells and provide a resource to study the development, physiology, and evolutionary conservation of mammalian ovarian follicle formation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Integrating single-cell transcriptomic data across different conditions, technologies, and species
Butler, A., Hoffman, P., Smibert, P., Papalexi, E., & Satija, R. (2018) · Nature Biotechnology · doi:10.1038/nbt.4096 · Cited by 13,174
Massively parallel digital transcriptional profiling of single cells
Zheng, G. X. Y., Terry, J. M., Belgrader, P., Ryvkin, P., Bent, Z. W., Wilson, R., Ziraldo, S. B., Wheeler, T. D., McDermott, G. P., Zhu, J., et al. (2017) · Nature Communications · doi:10.1038/ncomms14049 · Cited by 7,353
Keeney, S., Giroux, C. N., & Kleckner, N. (1997) · Cell · doi:10.1016/s0092-8674(00)81876-0 · Cited by 1,809
Development of Follicles in the Mammalian Ovary
Hirshfield, A. N. (1991) · International Review of Cytology · doi:10.1016/s0074-7696(08)61524-7 · Cited by 1,277
Female development in mammals is regulated by Wnt-4 signalling
Vainio, S., Heikkilä, M., Kispert, A., Chin, N., & McMahon, A. P. (1999) · Nature · doi:10.1038/17068 · Cited by 1,271
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
Tian, H., Biehs, B., Warming, S., Leong, K. G., Rangell, L., Klein, O. D., & de Sauvage, F. J. (2011) · Nature · doi:10.1038/nature10408 · Cited by 1,204
Retinoid signaling determines germ cell fate in mice
Bowles, J., Knight, D., Smith, C., Wilhelm, D., Richman, J., Mamiya, S., Yashiro, K., Chawengsaksophak, K., Wilson, M. J., Rossant, J., et al. (2006) · Science · doi:10.1126/science.1125691 · Cited by 1,011
Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation
Uhlenhaut, N. H., Jakob, S., Anlag, K., Eisenberger, T., Sekido, R., Kress, J., Treier, A.-C., Klugmann, C., Klasen, C., Holter, N. I., et al. (2009) · Cell · doi:10.1016/j.cell.2009.11.021 · Cited by 962
Carmon, K. S., Gong, X., Lin, Q., Thomas, A., & Liu, Q. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106083108 · Cited by 855
The Mammalian Ovary from Genesis to Revelation
Edson, M. A., Nagaraja, A. K., & Matzuk, M. M. (2009) · Endocrine Reviews · doi:10.1210/er.2009-0012 · Cited by 820
Cited by
Nicheformer: a foundation model for single-cell and spatial omics
Tejada-Lapuerta, A., Schaar, A. C., Gutgesell, R., Palla, G., Halle, L., Minaeva, M., Vornholz, L., Dony, L., Drummer, F., Richter, T., et al. (2025) · Nature Methods · doi:10.1038/s41592-025-02814-z · Cited by 100
Aging conundrum: A perspective for ovarian aging
Wu, J., Liu, Y., Song, Y., Wang, L., Ai, J., & Li, K. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.952471 · Cited by 73
Germ cell-specific eIF4E1b regulates maternal mRNA translation to ensure zygotic genome activation
Yang, G., Xin, Q., Feng, I., Wu, D., & Dean, J. (2023) · Genes & Development · doi:10.1101/gad.350400.123 · Cited by 25
Mills, M., Emori, C., Kumar, P., Boucher, Z., George, J., & Bolcun-Filas, E. (2025) · Developmental Biology · doi:10.1016/j.ydbio.2024.09.007 · Cited by 12
Metadata
- Authors
- Niu, W., & Spradling, A. C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2020-08-05
- Volume
- 117
- Issue
- 33
- Pages
- 20015-20026
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W3047354140
- Cited by
- 267
- References
- 84
- FWCI
- 25.13
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary. https://app.cochat.ai/papers/10.1073/pnas.2005570117
- The paper
- Niu, W., & Spradling, A. C. (2020). Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2005570117
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
