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Isolation of Microtubule Protein from Cultured Mouse Neuroblastoma Cells
Open accessAbstract
The addition of vinblastine to high-speed supernatants derived from homogenates of cultured mouse neuroblastoma cells results in the formation of a precipitate which has been characterized as microtubule protein by the following criteria: colchicine-binding activity, molecular weight, amino acid composition, and electrophoretic mobility. The method therefore permits the rapid isolation of microtubule protein from crude supernatants of neuroblastoma cells.
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Cited by
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Metadata
- Authors
- Olmsted, J. B., Carlson, K., Klebe, R., Ruddle, F., & Rosenbaum, J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1970-01
- Volume
- 65
- Issue
- 1
- Pages
- 129-136
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1982720718
- Cited by
- 315
- References
- 0
- FWCI
- 29.39
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Isolation of Microtubule Protein from Cultured Mouse Neuroblastoma Cells. https://app.cochat.ai/papers/10.1073/pnas.65.1.129
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- Olmsted, J. B., Carlson, K., Klebe, R., Ruddle, F., & Rosenbaum, J. (1970). Isolation of Microtubule Protein from Cultured Mouse Neuroblastoma Cells. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.65.1.129
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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