The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Mechanism of Activation of Catabolite-Sensitive Genes: A Positive Control System
Open accessAbstract
Catabolite repression is defined as the inhibition of enzyme induction by glucose or related substances. In the bacterium E. coli , the effect of glucose appears to be due to a lowering of the cyclic AMP level. A DNA-directed cell-free system for β-galactosidase synthesis has served as a model system for studying the mechanism of action of cyclic AMP. Previously, it was reported that in this system cyclic AMP is required for normal initiation of mRNA synthesis. A protein factor which acts in conjunction with the cyclic AMP has been partially purified. This protein factor has a high affinity for cyclic AMP. These and other results presented herein lead us to the conclusion that cyclic AMP and a protein factor called the catabolite gene activator protein are part of a positive control system for activating catabolite-sensitive genes.
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Cites
Magasanik, B. (1961) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1961.026.01.031 · Cited by 535
Adenosine 3‘,5‘-Phosphate in Escherichia coli
Makman, R. S., & Sutherland, E. W. (1965) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)97576-9 · Cited by 458
Cyclic AMP as an antagonist of catabolite repression in Escherichia coli
Ullmann, A., & Monod, J. (1968) · FEBS Letters · doi:10.1016/0014-5793(68)80100-0 · Cited by 188
Catabolite Sensitive Site of the lac Operon
Silverstone, A. E., Magasanik, B., Reznikoff, W. S., et al. (1969) · Nature · doi:10.1038/2211012b0 · Cited by 89
Cited by
Extracellular enzyme synthesis in the genus Bacillus
Priest, F. G. (1977) · Bacteriological Reviews · doi:10.1128/br.41.3.711-753.1977 · Cited by 815
Transcription activation by catabolite activator protein (CAP)
Busby, S., & Ebright, R. H. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1999.3161 · Cited by 800
Botsford, J. L., & Harman, J. G. (1992) · Microbiological Reviews · doi:10.1128/mr.56.1.100-122.1992 · Cited by 558
Körner, H., Sofia, H. J., & Zumft, W. G. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00066-4 · Cited by 461
Cyclic adenosine 5'-monophosphate in Escherichia coli
Pastan, I., & Adhya, S. (1976) · Bacteriological Reviews · doi:10.1128/br.40.3.527-551.1976 · Cited by 397
Metadata
- Authors
- Zubay, G., Schwartz, D., & Beckwith, J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1970-05
- Volume
- 66
- Issue
- 1
- Pages
- 104-110
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2061482652
- Cited by
- 431
- References
- 4
- FWCI
- 51.03
- Type
- journal article
- Language
- en
- Open access
- green
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- Zubay, G., Schwartz, D., & Beckwith, J. (1970). Mechanism of Activation of Catabolite-Sensitive Genes: A Positive Control System. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.66.1.104
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