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Quantitative Analysis of Urine Vapor and Breath by Gas-Liquid Partition Chromatography

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Pauling, Linus, Robinson, Arthur B., Teranishi, Roy, Cary, Paul·1971·Proceedings of the National Academy of Sciences

Abstract

When a human being is placed for several days on a completely defined diet, consisting almost entirely of small molecules that are absorbed from the stomach into the blood, intestinal flora disappear because of lack of nutrition. By this technique, the composition of body fluids can be made constant (standard deviation about 10%) after a few days, permitting significant quantitative analyses to be performed. A method of temperature-programmed gas-liquid partition chromatography has been developed for this purpose. It permits the quantitative determination of about 250 substances in a sample of breath, and of about 280 substances in a sample of urine vapor. The technique should be useful in the application of the principles of orthomolecular medicine.

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Metadata

Authors
Pauling, L., Robinson, A. B., Teranishi, R., & Cary, P.
Venue
Proceedings of the National Academy of Sciences
Published
1971-10
Volume
68
Issue
10
Pages
2374-2376
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2023002358
Cited by
1,025
References
0
FWCI
2.49
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Quantitative Analysis of Urine Vapor and Breath by Gas-Liquid Partition Chromatography. https://app.cochat.ai/papers/10.1073/pnas.68.10.2374
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Pauling, L., Robinson, A. B., Teranishi, R., & Cary, P. (1971). Quantitative Analysis of Urine Vapor and Breath by Gas-Liquid Partition Chromatography. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.68.10.2374

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.