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Cited by 297

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

Degradation of Abnormal Proteins in Escherichia coli

Open access
Goldberg, Alfred L.·1972·Proceedings of the National Academy of Sciences
DOI 10.1073/pnas.69.2.422
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Abstract

Evidence is presented that E. coli contains a mechanism for selective degradation of abnormal proteins. Unfinished polypeptides containing puromycin, proteins containing frequent errors in translation, such as those synthesized by strains containing a ram mutation or a missense suppressor, and proteins containing amino-acid analogs were degraded more rapidly than were normal cell proteins. The degradation of analog- or puromycin-containing proteins appears to be an energy-dependent process. Unlike normal proteins, such proteins were degraded at similar rates by growing and by nongrowing cells.

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Metadata

Authors
Goldberg, A. L.
Venue
Proceedings of the National Academy of Sciences
Publisher
Proceedings of the National Academy of Sciences
Published
1972-02
Volume
69
Issue
2
Pages
422-426
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
DOI
10.1073/pnas.69.2.422
OpenAlex
W1989185632
Cited by
297
References
20
FWCI
6.83
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Degradation of Abnormal Proteins in Escherichia coli. https://app.cochat.ai/papers/10.1073/pnas.69.2.422
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Goldberg, A. L. (1972). Degradation of Abnormal Proteins in Escherichia coli. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.69.2.422

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.