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Structure and Development of Neuronal Connections in Isogenic Organisms: Cellular Interactions in the Development of the Optic Lamina of Daphnia
Open accessAbstract
Some details of the growth and initial cellular interactions of optic nerve axons were examined in a parthenogenetic clone of Daphnia magna . Results are summarized as follows: ( i ) the final structure of the optic lamina is dependent upon interactions between growing optic nerve fibers and optic lamina neuroblasts closest to the midplane of the animal, which trigger the morphological differentiation of the neuroblasts; the specificity of connections is achieved by well-defined sequences of cell migration in the ganglion; ( ii ) only one of the eight optic nerve axons growing back from each ommatidium in the eye possesses a structure similar to the growth cones seen on termini of nerve fibers growing in vitro; and ( iii ) undifferentiated neuroblasts in the ganglion react to surface contact by this “lead axon” by enveloping the axon in a glial-like relationship.
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Citations
Cited by
Changeux, J.-P., & Danchin, A. (1976) · Nature · doi:10.1038/264705a0 · Cited by 1,448
Cell-to-substratum adhesion and guidance of axonal elongation
Letourneau, P. C. (1975) · Developmental Biology · doi:10.1016/0012-1606(75)90379-6 · Cited by 677
The structure of the ventral nerve cord of Caenorhabditis elegans
White, J. G., Southgate, E., Thomson, J. N., & Brenner, S. (1976) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1976.0086 · Cited by 616
Neuronal differentiation in the Drosophila ommatidium
Tomlinson, A., & Ready, D. F. (1987) · Developmental Biology · doi:10.1016/0012-1606(87)90239-9 · Cited by 537
Possible roles for cell-to-substratum adhesion in neuronal morphogenesis
Letourneau, P. C. (1975) · Developmental Biology · doi:10.1016/0012-1606(75)90378-4 · Cited by 444
Metadata
- Authors
- Lopresti, V., Macagno, E. R., & Levinthal, C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1973-02
- Volume
- 70
- Issue
- 2
- Pages
- 433-437
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1982039065
- Cited by
- 207
- References
- 0
- FWCI
- 4.09
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Structure and Development of Neuronal Connections in Isogenic Organisms: Cellular Interactions in the Development of the Optic Lamina of Daphnia. https://app.cochat.ai/papers/10.1073/pnas.70.2.433
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- Lopresti, V., Macagno, E. R., & Levinthal, C. (1973). Structure and Development of Neuronal Connections in Isogenic Organisms: Cellular Interactions in the Development of the Optic Lamina of Daphnia. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.70.2.433
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