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Structure and Development of Neuronal Connections in Isogenic Organisms: Cellular Interactions in the Development of the Optic Lamina of Daphnia

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Lopresti, V., Macagno, E. R., Levinthal, C.·1973·Proceedings of the National Academy of Sciences

Abstract

Some details of the growth and initial cellular interactions of optic nerve axons were examined in a parthenogenetic clone of Daphnia magna . Results are summarized as follows: ( i ) the final structure of the optic lamina is dependent upon interactions between growing optic nerve fibers and optic lamina neuroblasts closest to the midplane of the animal, which trigger the morphological differentiation of the neuroblasts; the specificity of connections is achieved by well-defined sequences of cell migration in the ganglion; ( ii ) only one of the eight optic nerve axons growing back from each ommatidium in the eye possesses a structure similar to the growth cones seen on termini of nerve fibers growing in vitro; and ( iii ) undifferentiated neuroblasts in the ganglion react to surface contact by this “lead axon” by enveloping the axon in a glial-like relationship.

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Metadata

Authors
Lopresti, V., Macagno, E. R., & Levinthal, C.
Venue
Proceedings of the National Academy of Sciences
Published
1973-02
Volume
70
Issue
2
Pages
433-437
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W1982039065
Cited by
207
References
0
FWCI
4.09
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Structure and Development of Neuronal Connections in Isogenic Organisms: Cellular Interactions in the Development of the Optic Lamina of Daphnia. https://app.cochat.ai/papers/10.1073/pnas.70.2.433
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Lopresti, V., Macagno, E. R., & Levinthal, C. (1973). Structure and Development of Neuronal Connections in Isogenic Organisms: Cellular Interactions in the Development of the Optic Lamina of Daphnia. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.70.2.433

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