The DOI matches its Crossref record.
Genetic Control of Basal Serum Immunoglobulin E Level and Its Effect on Specific Reaginic Sensitivity
Open accessAbstract
Studies of the distribution of total serum immunoglobulin E levels in nonallergic and allergic populations defined a cut-off point between low and high immunoglobulin E at 95 U/ml, based on Mendelian recessive inheritance of high immunoglobulin E level. Subsequent investigations of the distribution of total serum immunoglobulin E levels in 28 allergic families confirmed the recessive hypothesis. The results of quantitative skin tests in eight families, performed with between five and eight highly purified grass and ragweed pollen allergens per family, demonstrate that the immunoglobulin E-regulating gene exerts a profound effect on specific immunoglobulin E-mediated sensitivity, often masking the effect of HL-A associated immune response genes.
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Citations
Cited by
Baldini, M., Carla Lohman, I., Halonen, M., Erickson, R. P., Holt, P. G., & Martinez, F. D. (1999) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.20.5.3494 · Cited by 835
Dykewicz, M. S., Fineman, S., Skoner, D. P., Nicklas, R., Lee, R., Blessing-Moore, J., Li, J. T., Bernstein, I. L., Berger, W., Spector, S., et al. (1998) · Annals of Allergy, Asthma & Immunology · doi:10.1016/s1081-1206(10)63155-9 · Cited by 652
The Epidemiology and Genetics of Atopic Allergy
Marsh, D. G., Meyers, D. A., & Bias, W. B. (1981) · New England Journal of Medicine · doi:10.1056/nejm198112243052603 · Cited by 287
Self-citationGenetic analysis of allergic disease in twins
Hopp, R. J., Bewtra, A. K., Watt, G. D., Nair, N. M., & Townley, R. G. (1984) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(84)80018-4 · Cited by 283
Another smoking hazard: raised serum IgE concentration and increased risk of occupational allergy.
Zetterstrom, O., Osterman, K., Machado, L., & Johansson, S. G. (1981) · BMJ · doi:10.1136/bmj.283.6301.1215 · Cited by 282
Metadata
- Authors
- Marsh, D. G., Bias, W. B., & Ishizaka, K.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1974-09
- Volume
- 71
- Issue
- 9
- Pages
- 3588-3592
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2087206568
- Cited by
- 199
- References
- 0
- FWCI
- 8.38
- Type
- journal article
- Language
- en
- Open access
- green
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- Marsh, D. G., Bias, W. B., & Ishizaka, K. (1974). Genetic Control of Basal Serum Immunoglobulin E Level and Its Effect on Specific Reaginic Sensitivity. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.71.9.3588
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
