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Cited by 317

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells.

Open access
Wang, K, Ash, J F, Singer, S J·1975·Proceedings of the National Academy of Sciences

Abstract

A new high-molecular-weight protein, named filamin, was isolated from chicken gizzard. In chicken gizzard, filamin is present in an amount approximately 30-40% of that of myosin. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of highly purified filamin revealed a single polypeptide of about 250,000 daltons. Rabbit antibody directed against purified chicken gizzard filamin did not crossreact with myosin purified from the same source. By the use of microcomplement fixation and indirect immunofluorescent staining with antibodies to chicken gizzard filamin, an antigenically similar or identical protein was found to be widely distributed both in other organs of the chicken and in cultured cells of other species, but not in chicken skeletal muscle. In cultured cells, filamin was found largely to be arranged as a filamentous array very similar to that found for myosin. These data imply that filamin is a widely occurring and chemically conserved component of filaments is smooth muscle and non-muscle cells.

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Metadata

Authors
Wang, K., Ash, J. F., & Singer, S. J.
Venue
Proceedings of the National Academy of Sciences
Published
1975-11
Volume
72
Issue
11
Pages
4483-4486
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2062519237
Cited by
317
References
10
FWCI
9.79
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells. https://app.cochat.ai/papers/10.1073/pnas.72.11.4483
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Wang, K., Ash, J. F., & Singer, S. J. (1975). Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.72.11.4483

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.