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Cited by 412

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

The ovary as a source of alpha-ecdysone in an adult mosquito.

Open access
Hagedorn, H H, O'Connor, J D, Fuchs, M S, Sage, B, Schlaeger, D A, Bohm, M K·1975·Proceedings of the National Academy of Sciences

Abstract

The ovaries of the mosquito Aedes aegypti cultured in vitro secrete material that behaves like ecdysone in a radioimmunoassay. The material was identified as alpha-ecdysone by high-resolution liquid and gas-liquid chromatography. Secretion reached a maximum 16 hr after a blood meal as shown by bioassay and direct determination. Ovariectomy reduced the concentration of ecdysone in the adult after a blood meal. Qualitative analysis of whole-body extracts indicated beta-ecdysone to be the principal species present. Thus the ovaries appear to secrete a prohormone, alpha-ecdysone, which is converted to beta-ecdysone. Beta-ecdysone plays a significant role in stimulating egg development in the adult mosquito and may have reproductive roles in other insects.

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Metadata

Authors
Hagedorn, H. H., O'Connor, J. D., Fuchs, M. S., Sage, B., Schlaeger, D. A., & Bohm, M. K.
Venue
Proceedings of the National Academy of Sciences
Published
1975-08
Volume
72
Issue
8
Pages
3255-3259
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2095357678
Cited by
412
References
1
FWCI
6.80
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The ovary as a source of alpha-ecdysone in an adult mosquito. https://app.cochat.ai/papers/10.1073/pnas.72.8.3255
The paper
Hagedorn, H. H., O'Connor, J. D., Fuchs, M. S., Sage, B., Schlaeger, D. A., & Bohm, M. K. (1975). The ovary as a source of alpha-ecdysone in an adult mosquito. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.72.8.3255

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.