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Cited by 347

The DOI matches its Crossref record.

Vitamin A-containing lipocytes and formation of type III collagen in liver injury.

Open access
Kent, G, Gay, S, Inouye, T, Bahu, R, Minick, O T, Popper, H·1976·Proceedings of the National Academy of Sciences
DOI 10.1073/pnas.73.10.3719
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Abstract

Hepatocellular necrosis in carbon tetracholride-induced injury of rats is associated with an accumulation of lipocytes (perisinusoidal cells or Ito cells) containing fat droplets and giving vitamin A fluorescence. In the subsequent formation of connective tissue septa, transitional cells having morphologic characteristics of lipocytes and fibroblasts are abundant and are associated with the appearance of type III collage-. The features suggest that the lipocyte is the precursor of the fibroblasts responsible for parenchymal fibrillogenesis and under these conditions forms type III collagen. The process is a postulated link between hepatocellular necrosis and fibrosis.

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Metadata

Authors
Kent, G., Gay, S., Inouye, T., Bahu, R., Minick, O. T., & Popper, H.
Venue
Proceedings of the National Academy of Sciences
Publisher
Proceedings of the National Academy of Sciences
Published
1976-10
Volume
73
Issue
10
Pages
3719-3722
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
DOI
10.1073/pnas.73.10.3719
OpenAlex
W2021964163
Cited by
347
References
0
FWCI
9.15
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Vitamin A-containing lipocytes and formation of type III collagen in liver injury. https://app.cochat.ai/papers/10.1073/pnas.73.10.3719
The paper
Kent, G., Gay, S., Inouye, T., Bahu, R., Minick, O. T., & Popper, H. (1976). Vitamin A-containing lipocytes and formation of type III collagen in liver injury. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.73.10.3719

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.