The DOI matches its Crossref record.
Repair tracts in mismatched DNA heteroduplexes.
Open accessAbstract
Heteroduplexes with mismatches at four sites were constructed from separated strands of lambda DNA and used to transfect Escherichia coli under recombinationless conditions. The output phages from 967 single cells in one experiment and 1016 in another were analyzed to determine the pattern of mismatch repair. A wide range of repair frequencies was found among the mismatches studied. Repair involving two or more close sites in the same heteroduplex occurs much more often on thesamestrandthanonopposite strands.Analysis of the pattern of repair suggeststhat repair tracts initiate at mismatches, propagate preferentially in the 5'leads to 3' direction, and extend an average distance of ca 3000 nucleotides.
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Cited by
DNA repair mechanisms in dividing and non-dividing cells
Iyama, T., & Wilson, D. M. (2013) · DNA Repair · doi:10.1016/j.dnarep.2013.04.015 · Cited by 697
Critical DNA damage recognition functions of XPC‐hHR23B and XPA‐RPA in nucleotide excision repair
Thoma, B. S., & Vasquez, K. M. (2003) · Molecular Carcinogenesis · doi:10.1002/mc.10143 · Cited by 122
Metadata
- Authors
- Wagner, R., & Meselson, M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1976-11
- Volume
- 73
- Issue
- 11
- Pages
- 4135-4139
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2051909059
- Cited by
- 301
- References
- 0
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- green
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