The DOI matches its Crossref record.
Aplastic anemia: presence in human bone marrow of cells that suppress myelopoiesis.
Open accessAbstract
Bone marrow from a patient with aplastic anemia was shown by multiple criteria to have a block in early myeloid differentiation. This block was overcome in vitro by elimination of marrow lymphocytes. Furthermore, this differentiation block was transferred in vitro to normal marrow by coculturing with the patient's marrow. We suggest that some cases of aplastic anemia may be due to an immunologically based suppression of marrow cell differentiation rather than to a defect in stem cells or their necessary inductive environment.
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Citations
Cited by
Camitta, B., Thomas, E., Nathan, D., Gale, R., Kopecky, K., Rappeport, J., Santos, G., Gordon-Smith, E., & Storb, R. (1979) · Blood · doi:10.1182/blood.v53.3.504.504 · Cited by 422
Zoumbos, N. C., Gascon, P., Djeu, J. Y., & Young, N. S. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.1.188 · Cited by 330
Metadata
- Authors
- Kagan, W. A., Ascensão, J. A., Pahwa, R. N., Hansen, J. A., Goldstein, G., Valera, E. B., Incefy, G. S., Moore, M. A., & Good, R. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1976-08
- Volume
- 73
- Issue
- 8
- Pages
- 2890-2894
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1967465816
- Cited by
- 206
- References
- 0
- FWCI
- 17.41
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Aplastic anemia: presence in human bone marrow of cells that suppress myelopoiesis. https://app.cochat.ai/papers/10.1073/pnas.73.8.2890
- The paper
- Kagan, W. A., Ascensão, J. A., Pahwa, R. N., Hansen, J. A., Goldstein, G., Valera, E. B., Incefy, G. S., Moore, M. A., & Good, R. A. (1976). Aplastic anemia: presence in human bone marrow of cells that suppress myelopoiesis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.73.8.2890
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
