The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
On the physical basis for ambiguity in genetic coding interactions.
Open accessAbstract
We report the relative stabilities, in the form of complex lifetimes, of complexes between the tRNAs complementary, or nearly so, in their anticodons. The results show striking parallels with the genetic coding rules, including the wobble interaction and the role of modified nucleotides S2U and V (a 5-oxyacetic acid derivative of U). One important difference between the genetic code and the pairing rules in the tRNA-tRNA interaction is the stability in the latter of the short wobble pairs, which the wobble hypothesis excludes. We stress the potential of U for translational errors, and suggest a simple stereochemical basis for ribosome-mediated discrimination against short wobble pairs. Surprisingly, the stability of anticodon-anticodon complexes does not vary systematically on base sequence. Because of the close similarity to the genetic coding rules, it is tempting to speculate that the interaction between two RNA loops may have been part of the physical basis for the evolutionary origin of the genetic code, and that this mechanism may still be utilized by folding the mRNA on the ribosome into a loop similar to the anticodon loop.
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Citations
Cites
Selforganization of matter and the evolution of biological macromolecules
Eigen, M. (1971) · Die Naturwissenschaften · doi:10.1007/bf00623322 · Cited by 3,788
Ninio, J. (1974) · Journal of Molecular Biology · doi:10.1016/0022-2836(74)90586-5 · Cited by 136
Structural studies on a yeast glutamic acid tRNA specific to GAA codon
Yoshida, M., Takeishi, K., & Ukita, T. (1971) · Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · doi:10.1016/0005-2787(71)90555-7 · Cited by 69
Cited by
Codon usage in bacteria: correlation with gene expressivity
Gouy, M., & Gautier, C. (1982) · Nucleic Acids Research · doi:10.1093/nar/10.22.7055 · Cited by 1,250
Grosjean, H., & Fiers, W. (1982) · Gene · doi:10.1016/0378-1119(82)90157-3 · Cited by 851
Self-citationFourmy, D., Recht, M. I., Blanchard, S. C., & Puglisi, J. D. (1996) · Science · doi:10.1126/science.274.5291.1367 · Cited by 829
Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Ogle, J. M., Murphy, F. V., Tarry, M. J., & Ramakrishnan, V. (2002) · Cell · doi:10.1016/s0092-8674(02)01086-3 · Cited by 663
tRNA’s Wobble Decoding of the Genome: 40 Years of Modification
Agris, P. F., Vendeix, F. A. P., & Graham, W. D. (2007) · Journal of Molecular Biology · doi:10.1016/j.jmb.2006.11.046 · Cited by 543
Metadata
- Authors
- Grosjean, H. J., de Henau, S., & Crothers, D. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1978-02
- Volume
- 75
- Issue
- 2
- Pages
- 610-614
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2051531395
- Cited by
- 274
- References
- 3
- FWCI
- 9.14
- Type
- journal article
- Language
- en
- Open access
- green
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- Grosjean, H. J., de Henau, S., & Crothers, D. M. (1978). On the physical basis for ambiguity in genetic coding interactions. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.75.2.610
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