The DOI matches its Crossref record.
"Two out of three": an alternative method for codon reading.
Open accessAbstract
An alternative method for codon reading, whereby only the first two codon nucleotides are recognized by the anticodon, is discussed and the experimental evidence for this "two of three" reading method is reviewed. Misreading of codons by the "two out of three" method could pose a significant threat to the fidelity of protein synthesis unless the genetic code is organized in such a way as to prevent this method from being used when it might compromise translational fidelity. Inspection of the genetic code shows that it is arranged in such a way that the "two out of three" reading method can be used without translational errors.
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Cited by
Rewiring the keyboard: evolvability of the genetic code
Knight, R. D., Freeland, S. J., & Landweber, L. F. (2001) · Nature Reviews Genetics · doi:10.1038/35047500 · Cited by 435
An integrated, structure- and energy-based view of the genetic code
Grosjean, H., & Westhof, E. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw608 · Cited by 278
A Thermodynamic Basis for Prebiotic Amino Acid Synthesis and the Nature of the First Genetic Code
Higgs, P. G., & Pudritz, R. E. (2009) · Astrobiology · doi:10.1089/ast.2008.0280 · Cited by 218
Ling, J., Roy, H., Qin, D., Rubio, M. A. T., Alfonzo, J. D., Fredrick, K., & Ibba, M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704441104 · Cited by 45
Metadata
- Authors
- Lagerkvist, U.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1978-04
- Volume
- 75
- Issue
- 4
- Pages
- 1759-1762
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1992486617
- Cited by
- 269
- References
- 0
- FWCI
- 7.35
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
