Defect in 3'-phosphoadenosine 5'-phosphosulfate formation in brachymorphic mice.

Sugahara, K; Schwartz, N B

doi:10.1073/pnas.76.12.6615

Defect in 3'-phosphoadenosine 5'-phosphosulfate formation in brachymorphic mice.

Incorporation of 35SO42- into adenosine 5'-phosphosulfate (APS), 3'-phosphoadenosine 5'-phosphosulfate (PAPS), and chondroitin sulfate was simultaneously assessed with extracts prepared from epiphyseal cartilage of neonatal normal or homozygous brachymorphic mice. Radioactivity measured in APS, P…