The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Human leukocyte interferon: production, purification to homogeneity, and initial characterization.
Open accessAbstract
A method of fractionating proteins by high-performance liquid partition chromatography has been developed and used for isolation and purification to homogeneity of one of the species of human leukocyte interferon. The homogeneous interferon exhibited a sharp peak on high-performance liquid chromatography and a single narrow band on sodium dodecyl sulfate/polyacrylamide gel electrophoresis in the presence of 2-mercaptoethanol. Extraction of the gel gave a single sharp peak of antiviral activity coinciding with the protein band. The specific activity of pure interferon was found to be 2--4 X 10(8) units/mg, based on amino acid analysis. The molecular weight is 17,500--18,000.
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Citations
Cites
Virus interference. I. the interferon
Isaacs, A., & Lindenmann, J. (1957) · Proceedings of the Royal Society of London. Series B - Biological Sciences · doi:10.1098/rspb.1957.0048 · Cited by 3,451
Cited by
Interferons, interferon‐like cytokines, and their receptors
Pestka, S., Krause, C. D., & Walter, M. R. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00204.x · Cited by 1,766
Self-citationThe structure of eight distinct cloned human leukocyte interferon cDNAs
Goeddel, D. V., Leung, D. W., Dull, T. J., Gross, M., Lawn, R. M., McCandliss, R., Seeburg, P. H., Ullrich, A., Yelverton, E., & Gray, P. W. (1981) · Nature · doi:10.1038/290020a0 · Cited by 507
Convenient assay for interferons
Rubinstein, S., Familletti, P. C., & Pestka, S. (1981) · Journal of Virology · doi:10.1128/jvi.37.2.755-758.1981 · Cited by 481
Self-citationSynthesis in E. coli of a polypeptide with human leukocyte interferon activity
Nagata, S., Taira, H., Hall, A., Johnsrud, L., Streuli, M., Ecsödi, J., Boll, W., Cantell, K., & Weissmann, C. (1980) · Nature · doi:10.1038/284316a0 · Cited by 481
Human leukocyte and fibroblast interferons are structurally related
Taniguchi, T., Mantei, N., Schwarzstein, M., Nagata, S., Muramatsu, M., & Weissmann, C. (1980) · Nature · doi:10.1038/285547a0 · Cited by 277
Metadata
- Authors
- Rubinstein, M., Rubinstein, S., Familletti, P. C., Miller, R. S., Waldman, A. A., & Pestka, S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1979-02
- Volume
- 76
- Issue
- 2
- Pages
- 640-644
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1995631340
- Cited by
- 233
- References
- 1
- FWCI
- 18.55
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- Rubinstein, M., Rubinstein, S., Familletti, P. C., Miller, R. S., Waldman, A. A., & Pestka, S. (1979). Human leukocyte interferon: production, purification to homogeneity, and initial characterization. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.76.2.640
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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