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Cited by 392

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Inactivation of Ca conductance dependent on entry of Ca ions in molluscan neurons.

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Tillotson, D·1979·Proceedings of the National Academy of Sciences

Abstract

Inactivation of the Ca channel of Aplysia neurons was studied in the absence of potassium current in cells that were cesium-loaded with the aid of the ionophore nystatin. Inactivation was substantially decreased by methods that limited Ca entry. Depolarizations commensurate with the equilibrium potential of Ca resulted in minimal inactivation. Replacement of extracellular Ca by Ba also decreased inactivation. It is concluded that inactivation of the Ca channel is a function of the extent of Ca entry rather than membrane potential, thus differing fundamentally from the purely voltage-dependent mechanism for sodium inactivation.

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Metadata

Authors
Tillotson, D.
Venue
Proceedings of the National Academy of Sciences
Published
1979-03
Volume
76
Issue
3
Pages
1497-1500
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2045544906
Cited by
392
References
0
FWCI
13.79
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Inactivation of Ca conductance dependent on entry of Ca ions in molluscan neurons. https://app.cochat.ai/papers/10.1073/pnas.76.3.1497
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Tillotson, D. (1979). Inactivation of Ca conductance dependent on entry of Ca ions in molluscan neurons. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.76.3.1497

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.