The DOI matches its Crossref record.
Ubiquitous, interspersed repeated sequences in mammalian genomes.
Open accessAbstract
DNA base sequence comparisons demonstrate that the principal family of 300-nucleotide interspersed human DNA sequences, the repetitive double-strand regions of HeLa cell heterogeneous nuclear RNA, and specific RNA polymerase III in vitro transcripts of cloned human DNA sequences are all representatives of a closely related family of sequences. A segment of approximately 30 residues of these sequences is highly conserved in mammalian evolution because it is also present in the interspersed repeated DNA sequences of Chinese hamsters. Further DNA sequence comparisons demonstrate that a portion of this highly conserved segment of repetitive mamalian DNA sequence is similar to a sequence found within a low molecular weight RNA that hydrogen-bonds to poly(A)-terminated RNA molecules of Chinese hamsters and a sequence that forms half of a perfect inverted repeat near the origin of DNA replication in papovaviruses.
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Cited by
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Kern, S. E., Kinzler, K. W., Bruskin, A., Jarosz, D., Friedman, P., Prives, C., & Vogelstein, B. (1991) · Science · doi:10.1126/science.2047879 · Cited by 1,085
Gene Transfer and Molecular Cloning of the Human NGF Receptor
Chao, M. V., Bothwell, M. A., Ross, A. H., Koprowski, H., Lanahan, A. A., Buck, C. R., & Sehgal, A. (1986) · Science · doi:10.1126/science.3008331 · Cited by 449
A history of the human fetal globin gene duplication
Shen, S.-H., Slightom, J. L., & Smithies, O. (1981) · Cell · doi:10.1016/0092-8674(81)90302-0 · Cited by 332
Singular over-representation of an octameric palindrome, HIP1, in DNA from many cyanobacteria
Robinson, N. J., Robinson, P. J., Gupta, A., Bleasby, A. J., Whitton, B. A., & Morby, A. P. (1995) · Nucleic Acids Research · doi:10.1093/nar/23.5.729 · Cited by 87
Metadata
- Authors
- Jelinek, W. R., Toomey, T. P., Leinwand, L., Duncan, C. H., Biro, P. A., Choudary, P. V., Weissman, S. M., Rubin, C. M., Houck, C. M., Deininger, P. L., & Schmid, C. W.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1980-03
- Volume
- 77
- Issue
- 3
- Pages
- 1398-1402
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2117621343
- Cited by
- 539
- References
- 0
- FWCI
- 197.65
- Type
- journal article
- Language
- en
- Open access
- green
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- Jelinek, W. R., Toomey, T. P., Leinwand, L., Duncan, C. H., Biro, P. A., Choudary, P. V., Weissman, S. M., Rubin, C. M., Houck, C. M., Deininger, P. L., & Schmid, C. W. (1980). Ubiquitous, interspersed repeated sequences in mammalian genomes. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.77.3.1398
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