The DOI matches its Crossref record.
Purification and characterization of acidic fibroblast growth factor from bovine brain.
Open accessAbstract
Acidic brain fibroblast growth factor has been purified a minimum of 35,000-fold to apparent homogeneity by a combination of differential salt precipitation, ion exchange chromatography, gel filtration, isoelectric focusing, and hydrophobic chromatography on a C4 reversed-phase HPLC column. Two microheterogeneous forms of the molecule are obtained with apparent molecular masses of 16,600 and 16,800 daltons. The mitogen is highly active with half-maximal stimulation of BALB/c 3T3 fibroblasts at about 40 pg/ml in an assay using incorporation of [methyl-3H]thymidine into DNA.
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Cited by
Folkman, J., & Shing, Y. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)49853-0 · Cited by 2,654
The Fibroblast Growth Factor signaling pathway
Ornitz, D. M., & Itoh, N. (2015) · WIREs Developmental Biology · doi:10.1002/wdev.176 · Cited by 2,050
Fibroblast growth factors, their receptors and signaling
Powers, C. J., McLeskey, S. W., & Wellstein, A. (2000) · Endocrine-related cancer · doi:10.1677/erc.0.0070165 · Cited by 1,332
Abraham, J. A., Mergia, A., Whang, J. L., Tumolo, A., Friedman, J., Hjerrild, K. A., Gospodarowicz, D., & Fiddes, J. C. (1986) · Science · doi:10.1126/science.2425435 · Cited by 1,015
Hauschka, P. V., Mavrakos, A. E., Iafrati, M. D., Doleman, S. E., & Klagsbrun, M. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67143-1 · Cited by 869
Metadata
- Authors
- Thomas, K. A., Rios-Candelore, M., & Fitzpatrick, S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1984-01
- Volume
- 81
- Issue
- 2
- Pages
- 357-361
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2020263516
- Cited by
- 263
- References
- 0
- FWCI
- 11.33
- Type
- journal article
- Language
- en
- Open access
- green
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- Thomas, K. A., Rios-Candelore, M., & Fitzpatrick, S. (1984). Purification and characterization of acidic fibroblast growth factor from bovine brain. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.81.2.357
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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