The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II.
Open accessAbstract
Purified eukaryotic nuclear RNA polymerase II consists of three subspecies that differ in the apparent molecular masses of their largest subunit, designated IIo, IIa, and IIb for polymerase species IIO, IIA, and IIB, respectively. Subunits IIo, IIa, and IIb are the products of a single gene. We present here the amino acid composition of calf thymus subunits IIa and IIb and the C-terminal amino acid sequence of subunit IIa (IIo) inferred from the nucleotide sequence of part of the mouse gene encoding this RNA polymerase subunit. The calculated amino acid composition of the peptide unique to subunit IIa indicates that subunit IIa contains a domain rich in serine, proline, threonine, and tyrosine. The sequence at the 3' end of the mouse RNA polymerase II largest subunit gene reveals that the C-terminal domain consists of 52 repeats of a seven amino acid block with the consensus sequence Tyr-Ser-Pro-Thr-Ser-Pro-Ser. This sequence is also unusual in that it contains a high percentage of potential phosphorylation sites.
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Bentley, D. L. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3662 · Cited by 828
The RNA polymerase II CTD coordinates transcription and RNA processing
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DYNAMIC O-LINKED GLYCOSYLATION OF NUCLEAR AND CYTOSKELETAL PROTEINS
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Reversible Phosphorylation of the C-terminal Domain of RNA Polymerase II
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Self-citation
Metadata
- Authors
- Corden, J. L., Cadena, D. L., Ahearn, J. M., & Dahmus, M. E.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1985-12
- Volume
- 82
- Issue
- 23
- Pages
- 7934-7938
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1995733973
- Cited by
- 354
- References
- 24
- FWCI
- 5.54
- Type
- journal article
- Language
- en
- Open access
- green
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- Corden, J. L., Cadena, D. L., Ahearn, J. M., & Dahmus, M. E. (1985). A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.82.23.7934
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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