The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones.
Open accessAbstract
Growth-associated protein, GAP-43, is a polypeptide that is induced in neurons when they grow axons. We show by means of subcellular fractionation and immunohistochemical localization that GAP-43 is a component of neuronal growth cones as well as growing neurites; it is similar to a major phosphoprotein, pp46, of a growth cone-enriched subcellular fraction. These conclusions are consistent with the possibility that the induction of GAP-43/pp46 is an important event in the establishment of a productive growth state in which a neuron is competent to extend an axon.
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Cites
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Cited by
Molecular motors and mechanisms of directional transport in neurons
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Development of neuronal polarity: GAP-43 distinguishes axonal from dendritic growth cones
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Anatomical distribution of the growth-associated protein GAP-43/B-50 in the adult rat brain
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Metadata
- Authors
- Meiri, K. F., Pfenninger, K. H., & Willard, M. B.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1986-05
- Volume
- 83
- Issue
- 10
- Pages
- 3537-3541
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2062898068
- Cited by
- 522
- References
- 14
- FWCI
- 11.71
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones. https://app.cochat.ai/papers/10.1073/pnas.83.10.3537
- The paper
- Meiri, K. F., Pfenninger, K. H., & Willard, M. B. (1986). Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.83.10.3537
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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