The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Insertion and/or deletion of many repeated DNA sequences in human and higher ape evolution.
Open accessAbstract
The total numbers of copies of two repeat families, L1 (Kpn I) and Alu, have been measured in the DNA of four higher apes by an accurate titration method. The number of members of the Alu family repeats in the four genomes are as follows: human, 910,000; chimpanzee, 330,000; gorilla, 410,000; orangutan, 580,000. For the Kpn I family (3'-ward higher frequency region) the number of copies in these genomes are as follows: human, 107,000; chimpanzee, 51,000; gorilla, 64,000; orangutan, 84,000. Thermal stability measurements show that, although the families of repeats are moderately divergent in sequence, little net sequence change has occurred during the evolution of the higher apes. Most or all of the members of these families of repeats are interspersed throughout the genome. Therefore, a large number of events of insertion and/or deletion of these DNA sequences has occurred during higher primate evolution.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
SINEs and LINEs: Highly repeated short and long interspersed sequences in mammalian genomes
Singer, M. F. (1982) · Cell · doi:10.1016/0092-8674(82)90194-5 · Cited by 431
Cited by
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
Yang, A. S. (2004) · Nucleic Acids Research · doi:10.1093/nar/gnh032 · Cited by 1,033
Molecular genetics of the LDL receptor gene in familial hypercholesterolemia
Hobbs, H. H., Brown, M. S., & Goldstein, J. L. (1992) · Human Mutation · doi:10.1002/humu.1380010602 · Cited by 921
THE LDL RECEPTOR LOCUS IN FAMILIAL HYPERCHOLESTEROLEMIA: Mutational Analysis of a Membrane Protein
Hobbs, H. H., Russell, D. W., Brown, M. S., & Goldstein, J. L. (1990) · Annual Review of Genetics · doi:10.1146/annurev.ge.24.120190.001025 · Cited by 553
Many human L1 elements are capable of retrotransposition
Sassaman, D. M., Dombroski, B. A., Moran, J. V., Kimberland, M. L., Naas, T. P., DeBerardinis, R. J., Gabriel, A., Swergold, G. D., & Kazazian, H. H. (1997) · Nature Genetics · doi:10.1038/ng0597-37 · Cited by 451
THE ISOCHORE ORGANIZATION OF THE HUMAN GENOME
Bernardi, G. (1989) · Annual Review of Genetics · doi:10.1146/annurev.ge.23.120189.003225 · Cited by 382
Metadata
- Authors
- Hwu, H. R., Roberts, J. W., Davidson, E. H., & Britten, R. J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1986-06
- Volume
- 83
- Issue
- 11
- Pages
- 3875-3879
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2009318535
- Cited by
- 180
- References
- 1
- FWCI
- 19.19
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Insertion and/or deletion of many repeated DNA sequences in human and higher ape evolution. https://app.cochat.ai/papers/10.1073/pnas.83.11.3875
- The paper
- Hwu, H. R., Roberts, J. W., Davidson, E. H., & Britten, R. J. (1986). Insertion and/or deletion of many repeated DNA sequences in human and higher ape evolution. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.83.11.3875
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
