The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Monte Carlo-minimization approach to the multiple-minima problem in protein folding.
Open accessAbstract
A Monte Carlo-minimization method has been developed to overcome the multiple-minima problem. The Metropolis Monte Carlo sampling, assisted by energy minimization, surmounts intervening barriers in moving through successive discrete local minima in the multidimensional energy surface. The method has located the lowest-energy minimum thus far reported for the brain pentapeptide [Met5]enkephalin in the absence of water. Presumably it is the global minimum-energy structure. This supports the concept that protein folding may be a Markov process. In the presence of water, the molecules appear to exist as an ensemble of different conformations.
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Cites
Principles that Govern the Folding of Protein Chains
Anfinsen, C. B. (1973) · Science · doi:10.1126/science.181.4096.223 · Cited by 7,096
Protein states and proteinquakes.
Ansari, A., Berendzen, J., Bowne, S. F., Frauenfelder, H., Iben, I. E., Sauke, T. B., Shyamsunder, E., & Young, R. D. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.15.5000 · Cited by 828
Cited by
Structural properties of nanoclusters: Energetic, thermodynamic, and kinetic effects
Baletto, F., & Ferrando, R. (2005) · Reviews of Modern Physics · doi:10.1103/revmodphys.77.371 · Cited by 1,811
Principles of docking: An overview of search algorithms and a guide to scoring functions
Halperin, I., Ma, B., Wolfson, H., & Nussinov, R. (2002) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.10115 · Cited by 1,294
Ab initio random structure searching
Pickard, C. J., & Needs, R. J. (2011) · Journal of Physics: Condensed Matter · doi:10.1088/0953-8984/23/5/053201 · Cited by 1,302
Dill, K. A., Ozkan, S. B., Shell, M. S., & Weikl, T. R. (2008) · Annual Review of Biophysics · doi:10.1146/annurev.biophys.37.092707.153558 · Cited by 1,163
Fraczkiewicz, R., & Braun, W. (1998) · Journal of Computational Chemistry · doi:10.1002/(sici)1096-987x(199802)19:3<319::aid-jcc6>3.0.co;2-w · Cited by 1,120
Metadata
- Authors
- Li, Z., & Scheraga, H. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1987-10
- Volume
- 84
- Issue
- 19
- Pages
- 6611-6615
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2013785414
- Cited by
- 1,468
- References
- 2
- FWCI
- 5.02
- Type
- journal article
- Language
- en
- Open access
- green
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- Li, Z., & Scheraga, H. A. (1987). Monte Carlo-minimization approach to the multiple-minima problem in protein folding. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.84.19.6611
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