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Cited by 432

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box.

Open access
Didier, D K, Schiffenbauer, J, Woulfe, S L, Zacheis, M, Schwartz, B D·1988·Proceedings of the National Academy of Sciences

Abstract

The expression of HLA class II genes is regulated by a series of cis-acting elements and trans-acting factors. Several cis-acting elements have been identified and have been termed the Z box, X box, Y box, octamer, and "TATA" box. The Y box contains an inverted CCAAT box. By probing a phage lambda gt11 library with double-stranded oligonucleotides, we have directly isolated a cDNA encoding a Y box-binding protein designated YB-1. YB-1 binding has an absolute requirement for the CCAAT box and relative specificity for the Y box. It has a Mr of 35,414, contains 18% basic residues, and contains putative nuclear localization signals. An inverse correlation of YB-1 and HLA-DR beta chain mRNA levels suggests that YB-1 is a negative regulatory factor.

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Crossref · 10.1073/pnas.85.19.7322

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Metadata

Authors
Didier, D. K., Schiffenbauer, J., Woulfe, S. L., Zacheis, M., & Schwartz, B. D.
Venue
Proceedings of the National Academy of Sciences
Published
1988-10
Volume
85
Issue
19
Pages
7322-7326
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2005260875
Cited by
432
References
2
FWCI
4.57
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box. https://app.cochat.ai/papers/10.1073/pnas.85.19.7322
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Didier, D. K., Schiffenbauer, J., Woulfe, S. L., Zacheis, M., & Schwartz, B. D. (1988). Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.85.19.7322

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.