The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A tool for multiple sequence alignment.
Open accessAbstract
Multiple sequence alignment can be a useful technique for studying molecular evolution and analyzing sequence-structure relationships. Until recently, it has been impractical to apply dynamic programming, the most widely accepted method for producing pairwise alignments, to comparisons of more than three sequences. We describe the design and application of a tool for multiple alignment of amino acid sequences that implements a new algorithm that greatly reduces the computational demands of dynamic programming. This tool is able to align in reasonable time as many as eight sequences the length of an average protein.
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Self-citationWu, T. T., & Kabat, E. A. (1970) · The Journal of Experimental Medicine · doi:10.1084/jem.132.2.211 · Cited by 1,340
Cited by
Thompson, J. D., Higgins, D. G., & Gibson, T. J. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.22.4673 · Cited by 64,617
Amino acid substitution matrices from protein blocks.
Henikoff, S., & Henikoff, J. G. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.22.10915 · Cited by 6,218
The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins.
Ballester, R., Marchuk, D., Boguski, M., Saulino, A., Letcher, R., Wigler, M., & Collins, F. (1990) · Cell · doi:10.1016/0092-8674(90)90151-4 · Cited by 847
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Metadata
- Authors
- Lipman, D. J., Altschul, S. F., & Kececioglu, J. D.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1989-06
- Volume
- 86
- Issue
- 12
- Pages
- 4412-4415
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1998139877
- Cited by
- 506
- References
- 3
- FWCI
- 6.32
- Type
- journal article
- Language
- en
- Open access
- green
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- Lipman, D. J., Altschul, S. F., & Kececioglu, J. D. (1989). A tool for multiple sequence alignment. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.86.12.4412
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